Detailed information NTG0529211

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: LLF72_RS10765
• Genome accession: NZ_CP068511
• Coordinates: 2121941..2122972 (-)
• Length: 343 a.a.
• NCBI ID: WP_011677213.1
• Uniprot ID: A0A166ZHD8
• Organism: Lactococcus cremoris strain F.2.7
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 2116941..2127972

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LLF72_RS10735 (LLF72_10525)	-	2118144..2118641 (-)	498	WP_011677211.1	nitroreductase family protein	-
LLF72_RS10740 (LLF72_10530)	-	2118628..2118837 (-)	210	WP_011677212.1	hypothetical protein	-
LLF72_RS10745 (LLF72_10535)	-	2118834..2119058 (-)	225	WP_021211256.1	hypothetical protein	-
LLF72_RS10750 (LLF72_10540)	-	2119125..2120015 (+)	891	WP_015082946.1	IS982 family transposase	-
LLF72_RS10755 (LLF72_10545)	kwcM	2120122..2121441 (-)	1320	WP_015082947.1	KxxxW cyclic peptide radical SAM maturase	-
LLF72_RS10760 (LLF72_10550)	-	2121509..2121622 (-)	114	WP_011836076.1	KxxxW-cyclized peptide pheromone	-
LLF72_RS10765 (LLF72_10555)	sepM	2121941..2122972 (-)	1032	WP_011677213.1	SepM family pheromone-processing serine protease	Regulator
LLF72_RS10770 (LLF72_10560)	coaD	2122956..2123456 (-)	501	WP_011677214.1	pantetheine-phosphate adenylyltransferase	-
LLF72_RS10775 (LLF72_10565)	rsmD	2123504..2124043 (-)	540	WP_031286167.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
LLF72_RS10780 (LLF72_10570)	-	2124213..2125433 (-)	1221	WP_011677216.1	MFS transporter	-
LLF72_RS10785 (LLF72_10575)	lmrP	2125513..2126739 (-)	1227	Protein_2096	multidrug efflux MFS transporter LmrP	-
LLF72_RS10790 (LLF72_10580)	-	2126927..2127421 (+)	495	WP_015082948.1	RNA polymerase sigma factor	-

Sequence

Protein

• Length: 343 a.a.
• Molecular weight: 37398.03 Da
• Isoelectric Point: 9.8499

>NTDB_id=529211 LLF72_RS10765 WP_011677213.1 2121941..2122972(-) (sepM) [Lactococcus cremoris strain F.2.7]
MKKKNKKISPKLKWGISIGLIIVALLVLVYPTNYYVEMPGTTEPLGKMVKVEGKKDEHKGDFFLTTVQIARANLATMIYS
HFNSFTSIYSEQEMTGGLNDAQFNRVNQFYMETAQNTAVYQAFKLANKPYELKYEGVYVLDIAKNSTFKNKLELSDTITA
VNGEEFKSSADMIAYVSKQKVGDSVTIEYTRIDGSKHKSTGKYIKIANGKTGIGIGLVDHTEVVTDPKVTVNAGSIGGPS
AGIMFTLEIYSQLTGKDLRGGREIAGTGTIEHDGSIGQIGGVDKKVATASKEGAKVFLVPDSGTKKESSNNYLGAKAAAK
KLKTKMKIVPVKTIQDALDYLEK

Nucleotide

• Length: 1032 bp

>NTDB_id=529211 LLF72_RS10765 WP_011677213.1 2121941..2122972(-) (sepM) [Lactococcus cremoris strain F.2.7]
ATGAAGAAAAAAAATAAAAAAATCAGTCCCAAATTAAAATGGGGCATCTCTATTGGTCTGATTATTGTCGCTCTCCTTGT
TTTAGTGTATCCAACAAATTACTATGTGGAAATGCCTGGAACAACCGAGCCATTAGGAAAAATGGTCAAAGTCGAAGGAA
AAAAAGATGAGCACAAAGGTGACTTTTTCCTTACTACCGTTCAAATTGCGCGCGCTAATCTTGCCACAATGATTTACAGT
CATTTTAATAGTTTTACAAGCATTTACAGTGAACAAGAAATGACCGGTGGCCTTAATGATGCGCAGTTCAATCGTGTCAA
CCAGTTTTACATGGAAACGGCACAAAATACAGCCGTTTATCAGGCCTTCAAGTTGGCAAATAAACCCTATGAACTGAAAT
ATGAAGGGGTTTATGTCCTTGATATCGCTAAAAATTCGACTTTTAAAAATAAATTGGAACTTTCGGACACGATTACAGCA
GTCAATGGGGAAGAATTTAAATCAAGTGCAGATATGATTGCTTACGTTTCGAAGCAAAAAGTCGGCGATTCAGTTACCAT
TGAATATACACGGATTGATGGAAGTAAACACAAGTCTACTGGAAAATATATCAAAATCGCTAATGGAAAAACTGGAATCG
GAATTGGACTAGTTGACCATACTGAAGTAGTCACAGACCCAAAAGTTACAGTCAATGCAGGTTCAATCGGTGGACCATCT
GCCGGAATAATGTTTACACTAGAGATTTACAGTCAGTTGACAGGTAAAGATTTACGTGGTGGTCGCGAAATAGCAGGAAC
TGGAACGATTGAACATGATGGAAGCATTGGCCAAATCGGTGGGGTTGATAAAAAAGTAGCTACTGCTAGCAAAGAAGGCG
CAAAAGTTTTCTTAGTTCCTGACTCAGGCACCAAAAAAGAAAGCAGCAATAACTATCTTGGAGCCAAAGCAGCCGCTAAA
AAATTAAAAACGAAGATGAAAATTGTTCCCGTCAAGACTATTCAGGACGCTTTAGATTATTTAGAAAAATAA

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (229-339)

• PDZ domain (PDZ_2) (135-193)

3D structure

• AlphaFold DB: A0A166ZHD8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	48.696	100	0.49