Detailed information NTG0517343

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: I6I02_RS01745
• Genome accession: NZ_CP066093
• Coordinates: 349675..351915 (+)
• Length: 746 a.a.
• NCBI ID: WP_198463685.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain FDAARGOS_1045
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 344675..356915

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6I02_RS01715 (I6I02_01715)	-	344846..345961 (+)	1116	WP_198463681.1	hypothetical protein	-
I6I02_RS01720 (I6I02_01720)	-	345974..346243 (-)	270	WP_008535312.1	GIY-YIG nuclease family protein	-
I6I02_RS01725 (I6I02_01725)	-	346247..347011 (-)	765	WP_073950335.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
I6I02_RS01730 (I6I02_01730)	-	347061..347996 (-)	936	WP_198463682.1	polysaccharide deacetylase family protein	-
I6I02_RS01735 (I6I02_01735)	-	348127..348882 (+)	756	WP_198463683.1	lysophospholipid acyltransferase family protein	-
I6I02_RS01740 (I6I02_01740)	comEA	348990..349685 (+)	696	WP_198463684.1	helix-hairpin-helix domain-containing protein	Machinery gene
I6I02_RS01745 (I6I02_01745)	comEC/celB	349675..351915 (+)	2241	WP_198463685.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
I6I02_RS01750 (I6I02_01750)	-	352001..353263 (+)	1263	WP_198463686.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
I6I02_RS01755 (I6I02_01755)	-	353329..353874 (+)	546	WP_022496136.1	GNAT family N-acetyltransferase	-
I6I02_RS01760 (I6I02_01760)	spxR	353867..355147 (+)	1281	WP_022496137.1	CBS-HotDog domain-containing transcription factor SpxR	-
I6I02_RS01765 (I6I02_01765)	-	355187..356047 (+)	861	WP_004183173.1	methionyl aminopeptidase	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84354.07 Da
• Isoelectric Point: 9.6868

>NTDB_id=517343 I6I02_RS01745 WP_198463685.1 349675..351915(+) (comEC/celB) [Streptococcus salivarius strain FDAARGOS_1045]
MWLKKAPISLFSLSLLIAALYFTIFVTNVYAIGAFVFLMVCFLKHHWKNKAALKLVGLVGSFFLVYFLFLHHRATIQDKQ
APVEINQVTLVADTLLVNGEQLSAIGKAKGQTYQVFYRLKSEKEQHFFKTTSQTLVLKGKINLSQATAQRNFQGFNYQSY
LASQGIYRIAQIERLDQVVPQKSLSPLAFFHQLRRRALVHIQTHFPSPMRHYMTGLLFGYLDKEFDEQSQLYTSLGIIHL
FALSGMQVGFFLGWFRYGLLRLGLPKDYLFIVLLPFSLCYGLMTGWTASVLRALVQSLLAEFGIKKLDNMGITLLLLFLL
LPHFLLTVGGVLSCSYAFLLCLFDFEDLSSLKKSIYTSLVLSLGILPFLTYYYGTFQPVSLILTAIFSIVFDSFLLPVLT
VFFALSGLVIFSQINSLFEWMESFLTWIQSWIGQPLILGKPSLFQFGLMIAVLVMLFDFWKKPQFRICLLMIFGLLMVWV
KHPLTNEVTVVDVGQGDSIFLRSMKGDTILIDVGGKVTFGTKEKWQESSQTSNAEKTLIPYLQARGVSQIDYLVLTHTDT
DHIGDLEEVAKCFKIKEICVSQGALTKSSFVKRLRTIKCPVHTLKAGDKLPMMGSNLQVLYPNKVGDGGNNDSIVLYGKL
LGSSFLFTGDLEKEGEEELMASYPTLRASVLKAGHHGSKGSSSEAFLNQLHPSLALVSAGENNRYKHPNDETIERFKQRH
IKILRTDKDGAIRFKGWFKWSSETVR

Nucleotide

• Length: 2241 bp

>NTDB_id=517343 I6I02_RS01745 WP_198463685.1 349675..351915(+) (comEC/celB) [Streptococcus salivarius strain FDAARGOS_1045]
ATGTGGCTTAAAAAAGCGCCAATCAGTCTTTTTTCCTTGTCTCTTTTAATAGCGGCCCTTTATTTTACGATTTTTGTCAC
TAATGTTTATGCTATTGGTGCTTTTGTCTTTCTTATGGTCTGTTTTTTGAAGCATCATTGGAAGAATAAGGCAGCCCTAA
AGTTGGTGGGACTTGTAGGTAGTTTCTTTTTGGTCTACTTTTTATTCTTGCACCACAGAGCTACTATACAAGATAAACAA
GCTCCTGTTGAAATCAATCAGGTGACTCTGGTTGCTGATACGCTATTGGTTAATGGTGAGCAATTATCCGCTATCGGTAA
GGCCAAGGGACAAACCTATCAGGTCTTTTACCGACTCAAATCTGAGAAGGAGCAGCATTTTTTCAAGACTACTAGCCAAA
CGTTGGTATTGAAGGGGAAAATAAACTTATCTCAAGCAACTGCTCAGCGTAATTTTCAAGGGTTTAATTATCAATCTTAT
CTAGCCAGTCAAGGCATTTATCGAATCGCTCAGATTGAGCGCTTGGACCAAGTGGTACCTCAAAAATCTCTATCTCCCCT
AGCTTTTTTCCATCAACTGAGGAGGAGGGCTTTGGTTCATATCCAGACGCACTTTCCTAGTCCTATGAGACACTATATGA
CAGGCCTGCTCTTTGGGTATTTGGATAAGGAGTTCGATGAGCAGAGCCAGCTTTACACAAGTTTAGGTATTATTCATCTA
TTCGCACTTTCGGGGATGCAAGTGGGCTTTTTTCTGGGATGGTTTCGCTACGGTCTCCTACGCTTAGGTCTTCCTAAAGA
TTATCTATTTATCGTCTTGCTGCCTTTTTCCTTATGTTATGGCCTAATGACAGGATGGACAGCTTCAGTCCTACGTGCCT
TGGTTCAAAGTTTGCTGGCTGAGTTTGGTATTAAAAAACTGGACAATATGGGAATAACCTTGCTTCTATTGTTTCTCTTG
TTACCTCATTTTCTCTTAACAGTGGGAGGTGTATTAAGTTGTTCCTATGCCTTCTTGTTGTGTTTGTTTGATTTTGAGGA
CTTGTCATCTTTAAAGAAATCAATCTATACGAGCTTGGTATTGAGTCTTGGGATTTTGCCCTTTCTAACTTACTATTATG
GAACCTTTCAACCAGTTAGTTTGATTCTCACTGCAATCTTTTCAATTGTATTTGATAGCTTTCTCTTGCCTGTCTTGACA
GTATTCTTTGCCCTCTCAGGACTGGTAATCTTTTCTCAAATCAACTCACTTTTTGAATGGATGGAGTCCTTTTTGACTTG
GATACAATCCTGGATAGGTCAACCTTTGATTTTAGGGAAACCTAGTTTGTTTCAGTTTGGCTTGATGATAGCAGTATTGG
TTATGCTCTTTGATTTTTGGAAAAAGCCTCAGTTTAGGATTTGTCTTTTGATGATTTTTGGACTTTTGATGGTCTGGGTC
AAACATCCTTTAACCAATGAGGTGACTGTGGTTGACGTTGGTCAGGGAGATAGTATTTTTCTGAGGAGTATGAAAGGCGA
TACCATCCTAATTGATGTGGGTGGCAAGGTGACGTTTGGAACTAAGGAAAAATGGCAAGAGTCTAGCCAGACGAGCAATG
CGGAGAAAACCTTGATTCCCTATCTACAGGCTAGAGGAGTGTCTCAAATTGATTATCTGGTCCTGACGCATACGGACACA
GATCATATTGGTGATTTGGAAGAAGTGGCCAAGTGTTTTAAGATTAAGGAAATCTGTGTCAGTCAGGGGGCTTTGACTAA
GTCTAGCTTTGTTAAAAGACTTCGGACTATAAAATGCCCAGTTCACACTCTAAAGGCTGGCGACAAATTACCCATGATGG
GAAGCAATCTACAGGTTCTTTATCCAAATAAAGTTGGTGATGGCGGTAACAATGATTCGATAGTTCTTTACGGAAAGCTA
TTAGGAAGCAGTTTTCTGTTTACCGGTGATTTGGAAAAAGAAGGAGAGGAGGAACTGATGGCCAGCTATCCAACTTTAAG
GGCAAGCGTCCTAAAAGCTGGACACCACGGTTCAAAAGGTTCTTCGTCTGAAGCTTTTTTGAACCAGCTGCACCCCTCCC
TTGCACTTGTTTCAGCTGGTGAGAACAATCGTTATAAACATCCAAATGATGAAACAATAGAACGTTTTAAGCAACGCCAC
ATTAAAATTTTACGAACAGATAAAGACGGAGCCATCCGTTTTAAGGGCTGGTTTAAATGGTCAAGTGAAACAGTCCGATA
A

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (30-171)

• Competence protein (Competence) (216-462)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-690)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	48.267	100	0.485
comEC/celB	Streptococcus mitis NCTC 12261	47.797	100	0.48
comEC/celB	Streptococcus pneumoniae Rx1	46.4	100	0.466
comEC/celB	Streptococcus pneumoniae D39	46.4	100	0.466
comEC/celB	Streptococcus pneumoniae R6	46.4	100	0.466
comEC/celB	Streptococcus pneumoniae TIGR4	46.061	100	0.462
comEC	Lactococcus lactis subsp. cremoris KW2	44.309	98.928	0.438