Detailed information NTG0514258

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: STMM8_RS03195
• Genome accession: NZ_CP065787
• Coordinates: 593556..594557 (+)
• Length: 333 a.a.
• NCBI ID: WP_004197422.1
• Uniprot ID: Q9L6X0
• Organism: Streptococcus thermophilus strain MM8
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 588556..599557

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STMM8_RS03175 (STMM8_03175)	smpB	589661..590125 (+)	465	WP_002950240.1	SsrA-binding protein SmpB	-
STMM8_RS03180 (STMM8_03180)	-	590279..591685 (+)	1407	WP_022096975.1	Cof-type HAD-IIB family hydrolase	-
STMM8_RS03185 (STMM8_03185)	-	591687..592052 (+)	366	WP_002950243.1	S1 RNA-binding domain-containing protein	-
STMM8_RS03190 (STMM8_03190)	-	592155..593240 (-)	1086	WP_011225703.1	Xaa-Pro peptidase family protein	-
STMM8_RS03195 (STMM8_03195)	ccpA	593556..594557 (+)	1002	WP_004197422.1	catabolite control protein A	Regulator
STMM8_RS03200 (STMM8_03200)	-	594615..594812 (+)	198	WP_014608125.1	hypothetical protein	-
STMM8_RS03205 (STMM8_03205)	-	594918..595682 (+)	765	WP_004197425.1	MmcQ/YjbR family DNA-binding protein	-
STMM8_RS03210 (STMM8_03210)	-	595697..596812 (+)	1116	WP_022096976.1	glycerate kinase	-
STMM8_RS03215 (STMM8_03215)	-	596851..597306 (-)	456	WP_022096977.1	YueI family protein	-
STMM8_RS03220 (STMM8_03220)	eno	597515..598819 (+)	1305	WP_022096978.1	surface-displayed alpha-enolase	-
STMM8_RS03225 (STMM8_03225)	-	598972..599156 (-)	185	Protein_573	hypothetical protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36597.53 Da
• Isoelectric Point: 5.8841

>NTDB_id=514258 STMM8_RS03195 WP_004197422.1 593556..594557(+) (ccpA) [Streptococcus thermophilus strain MM8]
MNTDETITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIVNSYFA
TLAKGIDDIATMYKYNIVLASSDDNEDHEVTVIHSLISKQVDGIIFMGHHLTEKIRAEFSRTRTPIVLAGTVDLEHQLPS
VNIDYKAAVEDCVTQLAKNNEKVAFVSGPLIDDINGKLRLAGYKSGLEKNNLSYNEGLVFEAKYSYKDGFELAQRVLNSG
ATAAYVGEDELAAGLLNGLFAAGKSVPEDFEIITSNDSPVTSYTRPNLSSINHPLYDLGAVSMRMLTKIMHKEELEDKDV
ILNHGLTLRQSTK

Nucleotide

• Length: 1002 bp

>NTDB_id=514258 STMM8_RS03195 WP_004197422.1 593556..594557(+) (ccpA) [Streptococcus thermophilus strain MM8]
ATGAATACTGATGAAACAATCACAATTTATGATGTAGCGCGTGAAGCTGGAGTATCGATGGCAACTGTTTCTCGTGTTGT
AAATGGTAACAAAAACGTAAAAGAAAACACCCGAAAAAAAGTGCTCGAAGTCATTGATCGTTTGGATTACCGTCCAAATG
CGGTTGCGCGTGGCTTGGCAAGTAAAAAAACAACTACTGTAGGAGTTGTCATTCCAAATATTGTAAATAGCTATTTTGCT
ACTCTAGCTAAAGGTATTGATGACATTGCAACCATGTATAAGTATAATATTGTTCTTGCTTCCAGTGATGATAATGAGGA
TCATGAAGTTACAGTCATTCATTCTCTAATTTCTAAACAAGTTGATGGTATTATTTTTATGGGACACCACCTGACAGAAA
AAATCCGTGCAGAATTCTCTCGTACCCGTACACCGATTGTTCTAGCAGGAACAGTTGATCTCGAACACCAATTACCAAGT
GTTAACATCGACTATAAAGCTGCCGTTGAGGATTGTGTAACGCAACTTGCTAAAAATAATGAAAAGGTTGCCTTTGTATC
AGGACCACTAATTGATGATATTAATGGCAAACTACGTTTGGCTGGGTATAAGTCTGGACTTGAAAAGAATAATTTGAGCT
ACAACGAAGGACTTGTCTTTGAAGCTAAATATAGCTATAAAGACGGCTTTGAGTTAGCACAACGTGTCTTGAACTCTGGT
GCCACTGCTGCCTATGTTGGGGAAGATGAATTGGCTGCAGGTCTCTTGAATGGTCTCTTTGCTGCAGGCAAATCAGTTCC
AGAAGATTTCGAAATCATCACAAGCAATGATTCACCGGTTACAAGCTACACACGTCCAAACCTTTCTAGTATAAACCATC
CTCTCTATGATTTAGGGGCAGTTAGCATGCGTATGTTGACTAAAATTATGCATAAGGAAGAACTTGAAGATAAAGACGTT
ATTCTTAATCATGGTCTAACTTTACGCCAGTCAACAAAATAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (182-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: Q9L6X0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	76.276	100	0.763
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	54.985	99.399	0.547