Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   SCR2_RS05675 Genome accession   NC_022245
Coordinates   1140960..1142312 (-) Length   450 a.a.
NCBI ID   WP_006268651.1    Uniprot ID   F9P8V4
Organism   Streptococcus constellatus subsp. pharyngis C818     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1135960..1147312
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SCR2_RS05665 (SCR2_1116) rnc 1138961..1139659 (-) 699 WP_003068697.1 ribonuclease III -
  SCR2_RS10000 - 1139795..1140060 (-) 266 Protein_1115 YbaN family protein -
  SCR2_RS05670 (SCR2_1117) vicX 1140155..1140958 (-) 804 WP_006268738.1 MBL fold metallo-hydrolase Regulator
  SCR2_RS05675 (SCR2_1118) micB 1140960..1142312 (-) 1353 WP_006268651.1 cell wall metabolism sensor histidine kinase VicK Regulator
  SCR2_RS05680 (SCR2_1119) yycF 1142305..1143006 (-) 702 WP_003035055.1 response regulator YycF -
  SCR2_RS05685 (SCR2_1120) - 1143307..1143639 (-) 333 WP_006268722.1 hypothetical protein -
  SCR2_RS05690 (SCR2_1121) - 1143666..1144979 (-) 1314 WP_006268747.1 glycosyltransferase family 4 protein -
  SCR2_RS05695 (SCR2_1122) - 1144981..1145979 (-) 999 WP_020997876.1 glycosyltransferase family 4 protein -
  SCR2_RS05700 (SCR2_1123) ccpA 1146071..1147075 (-) 1005 WP_003068684.1 catabolite control protein A Regulator

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51407.70 Da        Isoelectric Point: 4.7289

>NTDB_id=51014 SCR2_RS05675 WP_006268651.1 1140960..1142312(-) (micB) [Streptococcus constellatus subsp. pharyngis C818]
MIDNIRQFVVSRDFVFVLLILGFILVITLLSLENRRDNIRIRRLNQKVKDLIAGDYSEVLDMQGGPEITDITNSINDLSE
VIRLTHENLEQETKRLSSILSYMTDGVLATNRRGQIIMINDMATKQLGVKESEARKMNILKLLDVEDEYDLRDLITKVPV
LTIDSQDENGEFLSLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALS
EPVAPDFIKVSLDETNRMMRMVSDLLSLSRIDNATSHLDIELTNFTAFITFILNRFDKIRSQNDDKKYEIIRDYPINSIW
VEIDTDKMTQVIDNIINNAIKYSPDGGKITVSMKTTETQMILSISDEGLGIPKKDLPKIFDRFYRVDKARSRAQGGSGLG
LAIAKEIIKQHNGFIWAKSEYGKGSTFTIVLPYDKEAVKDDDWEEDELEG

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=51014 SCR2_RS05675 WP_006268651.1 1140960..1142312(-) (micB) [Streptococcus constellatus subsp. pharyngis C818]
ATGATTGATAATATTAGACAATTTGTTGTATCAAGGGATTTTGTTTTTGTCTTACTTATTTTAGGATTTATTTTGGTCAT
TACGCTGCTCTCCTTGGAAAACAGACGTGATAATATTCGTATTCGCCGATTGAATCAAAAAGTGAAGGATTTAATCGCGG
GAGATTATTCAGAAGTTTTAGATATGCAAGGTGGTCCGGAAATTACTGATATTACAAATAGTATCAATGACTTATCTGAG
GTAATTCGCCTAACGCATGAAAATTTAGAGCAAGAAACCAAACGCTTGTCTAGTATTTTGTCCTATATGACAGATGGTGT
TCTTGCGACCAATCGTCGTGGGCAGATTATTATGATTAATGATATGGCGACCAAGCAATTGGGAGTCAAAGAGTCTGAAG
CACGAAAGATGAATATCTTAAAATTGTTGGATGTTGAAGATGAATATGATTTACGAGACTTGATTACGAAAGTTCCAGTG
TTGACCATTGATTCGCAGGATGAAAATGGAGAGTTTTTAAGTTTACGTGTCCGATTTGCCTTGATTCGTCGAGAATCAGG
CTTTATTTCAGGGCTGGTTGCTGTGCTGCACGATACAACGGAGCAGGAGAAAGAGGAGCGTGAGCGGAGACTATTTGTTT
CCAATGTTAGTCATGAATTGCGTACTCCCTTGACCAGTGTCAAGTCTTATCTGGAAGCATTAGATGAAGGTGCCTTGTCA
GAACCAGTCGCACCAGATTTTATTAAGGTTTCGTTAGATGAAACCAATCGGATGATGCGCATGGTTTCGGACTTGCTGAG
TTTGTCACGTATTGACAATGCAACCAGTCATTTGGATATTGAATTGACGAATTTTACAGCTTTTATCACCTTTATTTTGA
ACCGTTTTGATAAAATCAGAAGCCAGAATGATGATAAAAAGTACGAAATTATCCGAGATTATCCGATTAACTCTATTTGG
GTCGAAATTGATACAGATAAGATGACACAGGTGATTGATAATATTATCAACAATGCCATTAAATATTCTCCTGACGGTGG
TAAGATCACAGTGAGTATGAAAACAACCGAGACCCAAATGATTTTGTCTATATCAGATGAGGGCCTAGGGATTCCTAAAA
AAGATTTGCCGAAAATTTTTGATAGATTTTATCGTGTAGACAAAGCAAGAAGTCGCGCCCAAGGTGGATCCGGACTGGGC
TTAGCCATTGCCAAAGAGATTATCAAGCAACATAACGGATTTATCTGGGCAAAGAGCGAGTACGGCAAAGGCTCGACGTT
TACAATCGTTCTGCCATATGACAAAGAAGCTGTCAAAGATGATGATTGGGAAGAAGATGAATTAGAAGGATAG

Domains

Predicted by InterProScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)

PAS fold (PAS)

(95-198)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB F9P8V4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

81.321

97.556

0.793
  vicK Streptococcus mutans UA159

70.905

90.889

0.644

Multiple sequence alignment