Detailed information    

insolico Bioinformatically predicted

Overview

Name   irvR   Type   Regulator
Locus tag   KU540_RS06115 Genome accession   NZ_CP077894
Coordinates   1249399..1250112 (-) Length   237 a.a.
NCBI ID   WP_001031454.1    Uniprot ID   A0A0H2XG68
Organism   Staphylococcus aureus strain 329     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1244399..1255112
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KU540_RS06085 (KU540_06045) sph 1244818..1245642 (-) 825 Protein_1187 sphingomyelin phosphodiesterase -
  KU540_RS06090 (KU540_06050) - 1245699..1246736 (-) 1038 WP_225805896.1 tyrosine-type recombinase/integrase -
  KU540_RS06095 (KU540_06055) - 1246927..1247640 (-) 714 WP_001549185.1 type II toxin-antitoxin system PemK/MazF family toxin -
  KU540_RS06100 (KU540_06060) - 1247718..1247900 (-) 183 WP_000694770.1 hypothetical protein -
  KU540_RS06105 (KU540_06065) - 1248104..1248445 (-) 342 WP_000591749.1 hypothetical protein -
  KU540_RS06110 (KU540_06070) - 1248451..1249383 (-) 933 WP_000759682.1 exonuclease domain-containing protein -
  KU540_RS06115 (KU540_06075) irvR 1249399..1250112 (-) 714 WP_001031454.1 XRE family transcriptional regulator Regulator
  KU540_RS06120 (KU540_06080) - 1250075..1250249 (+) 175 Protein_1194 transcriptional regulator -
  KU540_RS06125 (KU540_06085) - 1250246..1250509 (+) 264 WP_000854072.1 helix-turn-helix transcriptional regulator -
  KU540_RS06130 (KU540_06090) - 1250525..1250740 (+) 216 WP_001025404.1 MW1434 family type I TA system toxin -
  KU540_RS06135 (KU540_06095) - 1250729..1251058 (-) 330 WP_000128909.1 hypothetical protein -
  KU540_RS06140 (KU540_06100) - 1251145..1251857 (+) 713 Protein_1198 phage antirepressor KilAC domain-containing protein -
  KU540_RS06145 (KU540_06105) - 1251870..1252130 (+) 261 WP_000435343.1 hypothetical protein -
  KU540_RS06150 - 1252154..1252309 (-) 156 Protein_1200 hypothetical protein -
  KU540_RS06155 (KU540_06115) - 1252364..1252603 (+) 240 WP_001294156.1 hypothetical protein -
  KU540_RS06160 (KU540_06120) - 1252929..1253249 (+) 321 WP_225805895.1 DUF771 domain-containing protein -
  KU540_RS06165 (KU540_06125) - 1253246..1253407 (+) 162 WP_225805894.1 DUF1270 family protein -
  KU540_RS06170 (KU540_06130) - 1253499..1253759 (+) 261 WP_225805893.1 DUF1108 family protein -
  KU540_RS06175 (KU540_06135) - 1253767..1254003 (+) 237 WP_225805892.1 hypothetical protein -
  KU540_RS06180 (KU540_06140) - 1253996..1254475 (+) 480 WP_031904445.1 siphovirus Gp157 family protein -

Sequence

Protein


Download         Length: 237 a.a.        Molecular weight: 27017.58 Da        Isoelectric Point: 5.0545

>NTDB_id=510101 KU540_RS06115 WP_001031454.1 1249399..1250112(-) (irvR) [Staphylococcus aureus strain 329]
MNKERNIIIAKNIRKFLNDSNMSQKKLAELINIKPSTLSDYLNLRSNPSHGVIQRIADVFEVGKSDIDTTYKDDNDITSI
YNKLTPPRQENVLNYANEQLEEQNSKGDNVVDINSYKQEKTPVNVNGCVSAGVGERLHDETLFTEMVKGPIPTHDLALKV
NGDSMEPMFKDGEIIFVEKTHNIKNGQIGIFIIEEEAYVKKVFVEDDRLTLVSLNKDYDDLHFYRNESVRLIGKVIL

Nucleotide


Download         Length: 714 bp        

>NTDB_id=510101 KU540_RS06115 WP_001031454.1 1249399..1250112(-) (irvR) [Staphylococcus aureus strain 329]
ATGAACAAAGAAAGAAATATTATTATAGCCAAAAACATTAGAAAATTTCTCAACGATTCAAATATGTCTCAAAAGAAACT
TGCTGAACTCATTAACATAAAACCATCTACTTTAAGCGATTATTTAAATTTACGTTCCAACCCCTCTCACGGCGTTATAC
AAAGGATAGCTGATGTTTTCGAGGTTGGTAAAAGCGACATAGATACTACATACAAAGACGATAACGACATCACTTCCATA
TACAACAAACTCACACCTCCCCGCCAAGAAAACGTACTTAACTATGCAAATGAACAATTGGAAGAACAGAATTCTAAAGG
AGATAACGTTGTAGATATTAATTCATATAAACAGGAGAAAACTCCAGTTAACGTCAATGGTTGCGTCTCTGCTGGTGTAG
GAGAACGTTTACACGATGAAACGCTATTTACTGAAATGGTTAAAGGACCTATCCCCACACACGATTTAGCGTTAAAAGTA
AATGGTGATTCTATGGAACCTATGTTTAAAGATGGCGAAATCATATTTGTGGAGAAAACTCACAATATAAAGAATGGACA
AATTGGTATATTCATCATTGAAGAAGAAGCGTACGTTAAGAAAGTCTTTGTTGAAGATGATAGATTGACTCTAGTTTCAC
TAAATAAAGATTACGACGATCTACACTTTTATAGAAATGAAAGTGTGAGGTTAATTGGAAAAGTTATTTTATAA

Domains

Predicted by InterProScan.

Peptidase S24-like (Peptidase_S24)

(127-236)

Helix-turn-helix (HTH_3)

(13-63)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2XG68

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  irvR Streptococcus mutans UA159

33.929

100

0.401