Detailed information NTG0510091

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: KU540_RS03165
• Genome accession: NZ_CP077894
• Coordinates: 677741..679849 (-)
• Length: 702 a.a.
• NCBI ID: WP_225805933.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain 329
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 672741..684849

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KU540_RS03150 (KU540_03125)	-	675258..675485 (+)	228	WP_000932073.1	FeoA family protein	-
KU540_RS03155 (KU540_03130)	feoB	675497..677491 (+)	1995	WP_225805934.1	ferrous iron transport protein B	-
KU540_RS03160 (KU540_03135)	-	677504..677674 (+)	171	WP_000111116.1	FeoB-associated Cys-rich membrane protein	-
KU540_RS03165 (KU540_03140)	clpE	677741..679849 (-)	2109	WP_225805933.1	ATP-dependent Clp protease ATP-binding subunit ClpL	Regulator
KU540_RS03170 (KU540_03145)	-	680212..680733 (+)	522	WP_000262597.1	methylated-DNA--[protein]-cysteine S-methyltransferase	-
KU540_RS03175 (KU540_03150)	-	680903..682069 (-)	1167	WP_000151984.1	hydroxymethylglutaryl-CoA synthase	-
KU540_RS03180 (KU540_03155)	-	682324..683604 (+)	1281	WP_001191002.1	hydroxymethylglutaryl-CoA reductase, degradative	-
KU540_RS03185 (KU540_03160)	-	683743..684174 (-)	432	WP_000875614.1	CHAP domain-containing protein	-
KU540_RS03190 (KU540_03165)	-	684562..684780 (-)	219	WP_000011687.1	sterile alpha motif-like domain-containing protein	-

Sequence

Protein

• Length: 702 a.a.
• Molecular weight: 78289.64 Da
• Isoelectric Point: 4.6237

>NTDB_id=510091 KU540_RS03165 WP_225805933.1 677741..679849(-) (clpE) [Staphylococcus aureus strain 329]
MNNNFFNSDFDSILRRMMQDMQNSNQTSNKKYYINGKEVSPEELSQFTQQGGNHSAEQSAQAFQQAAQRQQGQQGGNGNY
LEQIGRNLTQEARDRLLDPVIGRDKEIQETAEVLSRRTKNNPILVGEAGVGKTAIVEGLAQAIVEGNVPAAIKDKEIISI
DISSLEAGTQYRGAFEENIQKLVEGVKSSQNAVLFFDEIHQIIGSGATGSDSGSKGLSDILKPALSRGEISIIGATTQDE
YRNNIMKDAALTRRFNEVLVNEPSAKDTVEILKGIREKFETHHQVKLPDDVLKSCVDLSIQYIPQRLLPDKAIDVLDITA
AHLSAQSPAVDKVETEKRISELENDKRKAVSAEEYKKADDIQNEIKSLQDKLENSNGEHTAVATVHDISDTIQRLTGIPV
SQMDDNDIERLKNISNRLRSKIIGQDQAVEMVSRAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLAIDLFGNKEA
LIRLDMSEYSDTTAVSKMIGTTAGYVGYDDNSNTLTEKVRRNPYSVILFDEIEKANPQILTLLLQVMDDGNLTDGQGNVI
NFKNTIVICTSNAGFGNGTDQEYDDIMQEMKKFFRPEFLNRFNGIVEFLHLDKESLQEIINLLLDDVQVTLDKKGITMNV
SQDAKDWLIEEGYDEELGARPLRRIVEQQARDKITDYYLDHTDVKHVDLDIEDNELVVKGKS

Nucleotide

• Length: 2109 bp

>NTDB_id=510091 KU540_RS03165 WP_225805933.1 677741..679849(-) (clpE) [Staphylococcus aureus strain 329]
ATGAATAACAATTTTTTCAATAGTGACTTCGATTCTATTTTACGAAGAATGATGCAAGACATGCAAAACTCAAATCAGAC
TAGTAACAAGAAATACTATATTAATGGTAAAGAAGTTTCACCGGAAGAATTATCACAATTTACGCAACAAGGTGGTAATC
ATTCTGCCGAACAAAGTGCGCAAGCTTTTCAACAAGCAGCACAAAGACAACAAGGGCAACAAGGTGGCAATGGCAATTAT
TTAGAACAAATTGGTCGTAACTTAACGCAAGAGGCTCGTGACAGATTATTAGATCCAGTCATCGGTCGTGATAAAGAAAT
CCAAGAAACTGCAGAAGTCTTAAGTAGACGCACTAAAAACAATCCTATCCTAGTCGGAGAAGCTGGAGTTGGTAAAACTG
CGATTGTCGAAGGTTTAGCGCAAGCAATCGTTGAAGGGAATGTACCTGCAGCCATCAAAGATAAAGAAATTATATCTATA
GATATTTCATCGCTTGAAGCTGGAACGCAATATCGTGGCGCCTTTGAAGAAAACATCCAAAAGTTAGTTGAAGGCGTTAA
ATCATCACAAAATGCTGTGCTCTTCTTTGACGAAATTCACCAAATCATCGGTTCCGGCGCAACAGGAAGTGATTCCGGTA
GTAAAGGGTTATCTGATATTTTAAAACCAGCATTAAGTCGTGGTGAAATTTCAATTATAGGTGCAACGACTCAAGATGAA
TATCGCAATAATATCATGAAAGACGCTGCATTAACACGTCGTTTTAACGAGGTACTGGTTAACGAACCAAGCGCAAAAGA
TACGGTTGAAATTTTAAAAGGAATTCGTGAAAAATTTGAAACACACCATCAAGTCAAATTACCTGATGACGTATTAAAGT
CATGTGTAGACTTATCCATTCAATATATTCCACAACGCCTATTACCTGACAAAGCAATCGATGTGTTAGATATTACAGCA
GCACATTTATCTGCGCAAAGTCCAGCTGTCGATAAAGTTGAAACTGAAAAACGAATTTCTGAATTAGAAAATGATAAACG
TAAAGCTGTAAGTGCTGAAGAATATAAAAAAGCTGACGACATTCAAAATGAAATCAAATCATTACAAGATAAATTAGAAA
ACAGTAATGGTGAACATACTGCTGTTGCTACAGTTCATGATATTTCAGATACTATTCAACGATTAACTGGTATTCCAGTT
TCTCAAATGGATGATAACGATATTGAACGTTTAAAAAATATTTCTAATCGTTTAAGAAGTAAAATCATAGGTCAAGACCA
AGCTGTAGAGATGGTTTCACGTGCAATTCGCCGTAATCGTGCTGGATTCGATGACGGCAACCGTCCAATTGGTAGCTTCC
TATTTGTCGGTCCTACTGGTGTTGGTAAAACAGAGCTTGCCAAACAGTTAGCCATTGATTTATTTGGTAATAAAGAGGCA
CTGATTCGACTTGATATGAGTGAATATAGTGATACTACTGCTGTTTCTAAAATGATTGGTACAACTGCTGGTTATGTCGG
TTATGACGATAATTCAAATACATTAACTGAAAAAGTACGACGCAATCCATATTCAGTCATTCTATTTGATGAAATTGAAA
AGGCTAATCCACAAATATTAACATTATTACTTCAAGTGATGGATGATGGTAATTTAACAGATGGTCAAGGTAACGTCATC
AACTTTAAAAACACAATCGTTATTTGTACGTCAAACGCTGGTTTTGGTAACGGTACAGACCAAGAATACGATGACATTAT
GCAAGAAATGAAAAAATTCTTCCGTCCTGAATTCCTTAACCGCTTCAATGGTATTGTGGAATTCTTACACCTAGATAAAG
AATCACTTCAAGAAATCATTAATTTATTGTTGGATGATGTCCAAGTAACACTAGATAAAAAAGGTATTACGATGAATGTC
TCTCAAGATGCAAAAGATTGGTTAATTGAAGAGGGATATGATGAAGAGTTAGGCGCACGCCCATTAAGACGTATTGTTGA
ACAACAAGCGCGTGACAAAATAACAGATTATTATTTAGATCATACAGACGTTAAACATGTGGATTTAGATATCGAAGACA
ATGAATTAGTCGTCAAAGGTAAATCATGA

Domains

Predicted by InterProScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (611-682)

• ATPase family associated with various cellular activities (AAA) (AAA) (123-257)

• AAA domain (Cdc48 subfamily) (AAA_2) (448-603)

• AAA lid domain (AAA_lid_9) (264-363)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	47.745	91.595	0.437
clpC	Lactococcus lactis subsp. cremoris KW2	44.91	95.157	0.427
clpE	Streptococcus pneumoniae Rx1	47.164	87.892	0.415
clpE	Streptococcus pneumoniae TIGR4	47.164	87.892	0.415
clpE	Streptococcus pneumoniae R6	47.164	87.892	0.415
clpE	Streptococcus pneumoniae D39	47.164	87.892	0.415
clpC	Bacillus subtilis subsp. subtilis str. 168	44.325	92.877	0.412
clpC	Streptococcus thermophilus LMD-9	43.602	90.171	0.393
clpC	Streptococcus thermophilus LMG 18311	43.286	90.171	0.39
clpC	Streptococcus pneumoniae TIGR4	42.973	88.177	0.379
clpC	Streptococcus pneumoniae Rx1	42.973	88.177	0.379
clpC	Streptococcus pneumoniae D39	42.973	88.177	0.379
clpC	Streptococcus mutans UA159	43.089	87.607	0.377
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	41.894	88.746	0.372