Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/sigX/comX2/sigX2   Type   Regulator
Locus tag   I2438_RS09040 Genome accession   NZ_CP065190
Coordinates   1829458..1829937 (-) Length   159 a.a.
NCBI ID   WP_012516276.1    Uniprot ID   B4U4V3
Organism   Streptococcus equi subsp. zooepidemicus strain SEZ36     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1824458..1834937
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I2438_RS09005 (HCFMJIKG_01789) - 1824799..1825560 (-) 762 WP_284730085.1 class I SAM-dependent DNA methyltransferase -
  I2438_RS09010 (HCFMJIKG_01790) rsfS 1825672..1826025 (-) 354 WP_021321124.1 ribosome silencing factor -
  I2438_RS09015 (HCFMJIKG_01791) yqeK 1826027..1826620 (-) 594 WP_021321125.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  I2438_RS09020 (HCFMJIKG_01792) - 1826617..1827249 (-) 633 WP_021321126.1 nicotinate-nucleotide adenylyltransferase -
  I2438_RS09025 (HCFMJIKG_01793) yhbY 1827333..1827641 (-) 309 WP_012516273.1 ribosome assembly RNA-binding protein YhbY -
  I2438_RS09030 (HCFMJIKG_01794) yqeH 1827668..1828786 (-) 1119 WP_012516274.1 ribosome biogenesis GTPase YqeH -
  I2438_RS09035 (HCFMJIKG_01795) - 1828786..1829313 (-) 528 WP_037579990.1 YqeG family HAD IIIA-type phosphatase -
  I2438_RS09040 (HCFMJIKG_01796) comX/sigX/comX2/sigX2 1829458..1829937 (-) 480 WP_012516276.1 hypothetical protein Regulator

Sequence

Protein


Download         Length: 159 a.a.        Molecular weight: 19128.13 Da        Isoelectric Point: 7.3117

>NTDB_id=507785 I2438_RS09040 WP_012516276.1 1829458..1829937(-) (comX/sigX/comX2/sigX2) [Streptococcus equi subsp. zooepidemicus strain SEZ36]
MTDDLVRLFDKIKPIIMKLRRHYYIQLWELDDWLQEGRLILYRLLVTYPELIEDEEKLYRYFKTKFSSYLKDVLRQQESQ
KRRFHKMAYEEIGAVGHAIPAGGLGVDDYVAYQLIVKEVEEQLTESELLQFRALIRGERFEGRRALLRKIGPYFQDFTG

Nucleotide


Download         Length: 480 bp        

>NTDB_id=507785 I2438_RS09040 WP_012516276.1 1829458..1829937(-) (comX/sigX/comX2/sigX2) [Streptococcus equi subsp. zooepidemicus strain SEZ36]
ATGACTGATGATTTAGTGAGGTTATTTGATAAGATCAAGCCTATTATTATGAAGCTAAGACGGCATTATTATATTCAGCT
GTGGGAGCTGGATGATTGGTTACAGGAGGGACGGTTGATCTTGTATCGGTTGTTGGTTACTTATCCAGAATTGATAGAGG
ATGAGGAGAAGCTGTACCGTTACTTTAAGACCAAGTTTTCCTCTTATTTGAAGGACGTGTTGCGGCAGCAGGAGAGTCAG
AAGCGTCGGTTTCATAAGATGGCTTATGAGGAGATTGGGGCGGTAGGCCATGCGATACCAGCAGGTGGCTTGGGAGTAGA
TGATTATGTGGCTTATCAGTTGATTGTGAAGGAGGTTGAGGAGCAATTGACAGAGAGCGAGCTGTTACAGTTTAGGGCTT
TGATCAGGGGAGAGCGGTTTGAGGGGAGACGGGCCTTGCTTCGCAAGATAGGACCTTACTTTCAGGACTTTACTGGCTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB B4U4V3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

68.987

99.371

0.686
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

68.987

99.371

0.686
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

68.987

99.371

0.686
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

68.987

99.371

0.686
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

68.987

99.371

0.686
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

68.987

99.371

0.686
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

48.387

97.484

0.472
  comX/sigX Streptococcus mutans UA159

46.497

98.742

0.459
  comX Streptococcus sobrinus strain NIDR 6715-7

45.752

96.226

0.44
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

40.667

94.34

0.384
  comX Streptococcus thermophilus LMD-9

39.216

96.226

0.377
  comX Streptococcus thermophilus LMG 18311

39.216

96.226

0.377
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

39.735

94.969

0.377
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

39.735

94.969

0.377
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

39.333

94.34

0.371
  comX/comX2 Streptococcus pneumoniae Rx1

38.411

94.969

0.365
  comX/comX1 Streptococcus pneumoniae Rx1

38.411

94.969

0.365
  comX/comX2 Streptococcus pneumoniae D39

38.411

94.969

0.365
  comX/comX2 Streptococcus pneumoniae R6

38.411

94.969

0.365
  comX/comX1 Streptococcus pneumoniae R6

38.411

94.969

0.365
  comX/comX1 Streptococcus pneumoniae D39

38.411

94.969

0.365
  comX/comX2 Streptococcus pneumoniae TIGR4

38.411

94.969

0.365
  comX/comX1 Streptococcus pneumoniae TIGR4

38.411

94.969

0.365
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

38.667

94.34

0.365