Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   SCRE_RS02120 Genome accession   NC_022236
Coordinates   411927..412559 (+) Length   210 a.a.
NCBI ID   WP_006267191.1    Uniprot ID   F9P4H6
Organism   Streptococcus constellatus subsp. pharyngis C232     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 406927..417559
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SCRE_RS02100 (SCRE_0414) - 407352..408092 (+) 741 WP_003028411.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  SCRE_RS02105 (SCRE_0415) stkP 408089..409972 (+) 1884 WP_020997630.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  SCRE_RS02110 (SCRE_0416) liaF 410235..410933 (+) 699 WP_020997631.1 cell wall-active antibiotics response protein LiaF -
  SCRE_RS02115 (SCRE_0417) - 410930..411925 (+) 996 WP_006267397.1 sensor histidine kinase -
  SCRE_RS02120 (SCRE_0418) vraR 411927..412559 (+) 633 WP_006267191.1 response regulator transcription factor Regulator
  SCRE_RS02125 (SCRE_0419) - 412606..414006 (+) 1401 WP_020997632.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  SCRE_RS02130 (SCRE_0420) - 414008..414400 (+) 393 WP_020997633.1 S1 RNA-binding domain-containing protein -
  SCRE_RS02135 (SCRE_0421) - 414520..414837 (-) 318 WP_006269734.1 DUF960 domain-containing protein -
  SCRE_RS02140 (SCRE_0422) - 414957..415490 (-) 534 WP_003070217.1 DUF402 domain-containing protein -
  SCRE_RS02145 (SCRE_0423) recX 415577..416353 (-) 777 WP_006267569.1 recombination regulator RecX Regulator
  SCRE_RS02150 (SCRE_0424) - 416417..417193 (-) 777 WP_006267458.1 aminoglycoside 3'-phosphotransferase -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23646.27 Da        Isoelectric Point: 4.7982

>NTDB_id=50377 SCRE_RS02120 WP_006267191.1 411927..412559(+) (vraR) [Streptococcus constellatus subsp. pharyngis C232]
MQILLVDDHEMVRLGLKSYLDLQDDVDVVVEASNGREGVEKALALRPDVIMMDIVMPEMSGIEATLAILKEWPEAKILIL
TSYLDNEKIYPVLDAGAKGYMLKTSSADDILRAVRKVAKGELAIETEVSQKVEYHRNHIELHEELTARERDILGLLAKGY
ENQRIADELFISLKTVKTHVSNILSKLAVSDRTQAVVYAFQHHLVPQDDI

Nucleotide


Download         Length: 633 bp        

>NTDB_id=50377 SCRE_RS02120 WP_006267191.1 411927..412559(+) (vraR) [Streptococcus constellatus subsp. pharyngis C232]
ATGCAGATTTTATTAGTAGATGACCATGAGATGGTACGACTTGGCTTGAAAAGTTATTTGGATTTACAAGATGATGTTGA
TGTAGTGGTAGAAGCTTCAAACGGTCGTGAAGGAGTTGAAAAAGCTTTAGCATTACGACCAGATGTTATTATGATGGATA
TTGTTATGCCTGAAATGAGTGGAATTGAAGCAACTCTAGCTATTTTAAAAGAATGGCCTGAAGCTAAGATTCTCATTCTG
ACTTCTTATTTGGATAATGAAAAAATTTACCCAGTTTTAGATGCAGGAGCTAAAGGATACATGCTTAAAACATCTAGTGC
TGACGATATCTTACGAGCAGTTCGAAAGGTAGCCAAGGGTGAACTTGCTATTGAAACAGAGGTCAGTCAGAAAGTGGAAT
ACCATCGAAATCATATTGAATTACATGAAGAGCTAACAGCGCGTGAGCGCGATATTTTAGGACTACTGGCGAAGGGGTAT
GAAAATCAACGCATAGCAGATGAGTTGTTTATTTCTTTAAAGACAGTGAAAACGCATGTGTCGAATATTTTGTCCAAATT
GGCAGTAAGTGATCGTACACAAGCTGTTGTCTATGCCTTCCAGCATCACCTCGTCCCACAGGATGATATTTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB F9P4H6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

53.883

98.095

0.529
  degU Bacillus subtilis subsp. subtilis str. 168

38.839

100

0.414

Multiple sequence alignment