Detailed information    

insolico Bioinformatically predicted

Overview

Name   comK/comK1   Type   Regulator
Locus tag   HWI40_RS08400 Genome accession   NZ_CP064540
Coordinates   1781465..1782040 (-) Length   191 a.a.
NCBI ID   WP_001829272.1    Uniprot ID   -
Organism   Staphylococcus epidermidis strain UMCG367     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1773962..1780959 1781465..1782040 flank 506


Gene organization within MGE regions


Location: 1773962..1782040
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HWI40_RS08305 (HWI40_08235) - 1773974..1774207 (-) 234 Protein_1601 AAA family ATPase -
  HWI40_RS08310 (HWI40_08240) - 1774582..1774905 (+) 324 WP_002456098.1 hypothetical protein -
  HWI40_RS08315 - 1774888..1775022 (-) 135 WP_002439268.1 hypothetical protein -
  HWI40_RS08320 - 1775036..1775248 (-) 213 Protein_1604 DUF771 domain-containing protein -
  HWI40_RS08325 (HWI40_08245) - 1775252..1776016 (-) 765 WP_002439267.1 phage regulatory protein/antirepressor Ant -
  HWI40_RS08330 (HWI40_08250) - 1776066..1776272 (+) 207 WP_002439266.1 hypothetical protein -
  HWI40_RS08335 (HWI40_08255) - 1776261..1776425 (-) 165 WP_002439265.1 hypothetical protein -
  HWI40_RS08340 (HWI40_08260) - 1776422..1776676 (-) 255 WP_002439263.1 helix-turn-helix transcriptional regulator -
  HWI40_RS08345 (HWI40_08265) - 1776870..1777199 (+) 330 WP_002439260.1 helix-turn-helix domain-containing protein -
  HWI40_RS08350 (HWI40_08270) - 1777211..1777672 (+) 462 WP_002439258.1 ImmA/IrrE family metallo-endopeptidase -
  HWI40_RS08355 (HWI40_08275) - 1777688..1778206 (+) 519 WP_002439256.1 hypothetical protein -
  HWI40_RS08360 (HWI40_08280) - 1778208..1778651 (+) 444 WP_002439254.1 hypothetical protein -
  HWI40_RS08365 (HWI40_08285) - 1778724..1778918 (+) 195 WP_002439253.1 hypothetical protein -
  HWI40_RS08370 (HWI40_08290) - 1778987..1779502 (+) 516 WP_002439252.1 hypothetical protein -
  HWI40_RS08375 (HWI40_08295) - 1779504..1779839 (+) 336 WP_002439251.1 hypothetical protein -
  HWI40_RS08380 (HWI40_08300) - 1779895..1780293 (+) 399 Protein_1616 phage integrase SAM-like domain-containing protein -
  HWI40_RS08385 (HWI40_08305) - 1780399..1780959 (+) 561 Protein_1617 site-specific integrase -
  HWI40_RS08400 (HWI40_08320) comK/comK1 1781465..1782040 (-) 576 WP_001829272.1 competence protein ComK Regulator

Sequence

Protein


Download         Length: 191 a.a.        Molecular weight: 22782.87 Da        Isoelectric Point: 9.2887

>NTDB_id=502870 HWI40_RS08400 WP_001829272.1 1781465..1782040(-) (comK/comK1) [Staphylococcus epidermidis strain UMCG367]
MTHLPETIYVIRKGDMVIRPKYDEYQQTNGTEIIRFDQTRKESPFKVQRIIERSCKFYGNNYISKKAETNRITGISSKPP
ILLTPLFPTYFFPTHSDRQEENIWINMHYIENVKELKNRKSKIIFANGDSLTLNVSFHSLWHQYTNAIIYYYMVDKQSRM
KSNNPEQPIDYNQSSLNIFEALSRYSLFEEN

Nucleotide


Download         Length: 576 bp        

>NTDB_id=502870 HWI40_RS08400 WP_001829272.1 1781465..1782040(-) (comK/comK1) [Staphylococcus epidermidis strain UMCG367]
ATGACACATTTACCCGAAACGATTTATGTTATACGAAAAGGTGATATGGTAATACGACCTAAATATGATGAATATCAGCA
AACAAATGGTACTGAAATTATCAGATTTGATCAAACTCGCAAAGAAAGTCCATTTAAAGTACAGAGAATTATCGAAAGAT
CATGTAAATTTTATGGTAATAATTATATTAGTAAAAAAGCAGAAACGAATCGTATTACTGGAATCTCTAGTAAACCACCT
ATTTTACTTACGCCTCTTTTTCCTACTTATTTTTTTCCAACTCACTCAGACCGTCAAGAAGAAAATATATGGATTAATAT
GCATTATATTGAAAATGTTAAAGAACTTAAAAATCGTAAGAGTAAAATAATTTTTGCGAATGGTGATTCGTTAACGCTCA
ATGTATCATTTCATAGCTTGTGGCATCAATATACGAATGCAATCATCTATTATTACATGGTAGATAAGCAATCACGAATG
AAATCTAACAACCCTGAACAACCCATTGACTATAATCAGTCTTCTCTAAATATTTTCGAGGCGCTCTCACGCTACTCCCT
TTTTGAAGAAAATTAG

Domains

Predicted by InterproScan.

ComK protein (ComK)

(7-158)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comK/comK1 Staphylococcus aureus MW2

76.757

96.859

0.743
  comK/comK1 Staphylococcus aureus N315

76.757

96.859

0.743