Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   STH8232_RS05805 Genome accession   NC_017581
Coordinates   1112398..1113738 (-) Length   446 a.a.
NCBI ID   WP_014621665.1    Uniprot ID   -
Organism   Streptococcus thermophilus JIM 8232     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1107398..1118738
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STH8232_RS05775 (STH8232_1335) - 1107518..1107904 (-) 387 WP_002953113.1 DUF1934 domain-containing protein -
  STH8232_RS10640 - 1107996..1108874 (-) 879 Protein_1058 GNAT family N-acetyltransferase -
  STH8232_RS05785 (STH8232_1340) yidA 1109082..1109891 (+) 810 WP_011226081.1 sugar-phosphatase -
  STH8232_RS05790 (STH8232_1341) - 1109893..1111107 (+) 1215 WP_004197368.1 aminoacyltransferase -
  STH8232_RS05795 (STH8232_1343) - 1111159..1111520 (-) 362 Protein_1061 YbaN family protein -
  STH8232_RS05800 (STH8232_1344) vicX 1111580..1112392 (-) 813 WP_011681204.1 MBL fold metallo-hydrolase Regulator
  STH8232_RS05805 (STH8232_1345) vicK 1112398..1113738 (-) 1341 WP_014621665.1 cell wall metabolism sensor histidine kinase VicK Regulator
  STH8232_RS05810 (STH8232_1346) vicR 1113731..1114438 (-) 708 WP_011226084.1 response regulator YycF Regulator
  STH8232_RS05815 (STH8232_1347) - 1114962..1115729 (+) 768 WP_011681207.1 amino acid ABC transporter ATP-binding protein -
  STH8232_RS05820 (STH8232_1348) - 1115741..1116574 (+) 834 WP_011681208.1 transporter substrate-binding domain-containing protein -
  STH8232_RS05825 (STH8232_1349) - 1116592..1117290 (+) 699 WP_014608374.1 amino acid ABC transporter permease -
  STH8232_RS05830 (STH8232_1350) - 1117302..1117952 (+) 651 WP_014608375.1 amino acid ABC transporter permease -

Sequence

Protein


Download         Length: 446 a.a.        Molecular weight: 50806.14 Da        Isoelectric Point: 5.3933

>NTDB_id=48996 STH8232_RS05805 WP_014621665.1 1112398..1113738(-) (vicK) [Streptococcus thermophilus JIM 8232]
MTSIVLNITSFELALLFTLLFVAFYFIFLAYRDYQQVKNIRKLTKRVKSLMAGNYSEKLRIKGDSELLELANSLNDLSDV
FRLTHENLIQEKNRLSSVLSYMSDGVIATNRLGQITMINSTAQRLLNLDRETATQMSILDILDGENPYTYSELLSKTPEI
HLSRRDANDEFVTLRVNFALIRKESGFISGLVAVLHDATEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALNE
EIAPNFIKVSLDETNRMMRMISDLLALSRIDNKSTQLNVEMTNFTAFMTYILNRFGQIKSQETNPGKSYEIIRDYPVNSI
WVEIDTDKMTQVIDNILNNAIKYSPDGGKITVSMKTTDTQLIVSISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTGL
GLSIAKEIVKQHNGFIWAKSEYGKGSTFTIVLPYDQDAMMVDEWEM

Nucleotide


Download         Length: 1341 bp        

>NTDB_id=48996 STH8232_RS05805 WP_014621665.1 1112398..1113738(-) (vicK) [Streptococcus thermophilus JIM 8232]
ATGACTAGTATTGTCTTAAATATTACAAGCTTTGAACTAGCCTTACTCTTTACGCTCCTCTTTGTTGCTTTCTATTTCAT
TTTTCTAGCTTATCGTGATTATCAACAGGTCAAAAATATCCGAAAGTTGACTAAGAGAGTCAAATCCCTTATGGCAGGTA
ATTATAGTGAAAAATTACGCATAAAGGGAGATTCAGAGCTTTTAGAGCTAGCTAATAGCTTGAATGATTTGTCGGACGTC
TTTCGTTTGACACATGAAAATCTAATCCAGGAAAAAAACCGCTTATCATCTGTCCTTTCGTACATGAGTGACGGGGTTAT
TGCGACCAATCGCCTTGGTCAGATTACTATGATTAATAGTACTGCCCAACGCTTGTTGAATTTAGATCGCGAAACTGCGA
CTCAGATGTCTATTTTGGATATATTAGATGGTGAGAATCCCTATACCTATAGTGAATTGTTGTCTAAGACACCCGAAATC
CATCTGTCGCGTCGAGATGCTAACGATGAATTTGTGACGCTACGTGTTAATTTTGCATTAATTCGTAAGGAATCTGGTTT
TATTTCAGGTCTGGTAGCCGTTCTTCATGATGCCACTGAGCAGGAAAAAGAAGAGCGCGAACGCCGTCTCTTCGTATCAA
ATGTTAGTCACGAATTGCGGACGCCTTTAACTTCTGTGAAATCCTATCTTGAAGCGCTTGATGATGGTGCTCTCAACGAA
GAGATTGCTCCAAACTTTATCAAAGTTTCTTTAGATGAAACCAACCGCATGATGCGTATGATTTCTGACCTCTTGGCATT
ATCTCGAATTGACAATAAAAGCACACAGCTTAATGTTGAAATGACAAACTTTACAGCCTTTATGACCTATATCTTGAATC
GGTTTGGTCAAATTAAGAGTCAAGAAACTAATCCAGGTAAGTCTTATGAAATCATTCGAGATTACCCAGTAAACTCTATT
TGGGTGGAAATTGATACTGATAAGATGACCCAGGTCATAGATAATATACTTAATAATGCCATCAAGTATTCTCCTGATGG
TGGGAAAATTACAGTATCTATGAAAACGACAGACACTCAGTTGATTGTTTCTATTTCTGACCAAGGTTTAGGAATTCCTA
AAAAAGATTTACCTCTGATTTTTGACCGTTTTTACCGTGTTGATAAGGCCAGAAGTCGTGCTCAGGGTGGAACAGGACTT
GGCTTATCCATTGCAAAAGAAATTGTTAAACAACATAATGGCTTCATTTGGGCTAAGAGTGAGTATGGTAAGGGATCAAC
TTTTACAATTGTGCTTCCATATGACCAGGACGCAATGATGGTCGATGAATGGGAGATGTAG

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(208-272)

PAS fold (PAS)

(94-197)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-435)

HAMP domain (HAMP)

(37-79)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

74.396

92.825

0.691
  micB Streptococcus pneumoniae Cp1015

65.904

97.982

0.646

Multiple sequence alignment