Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   IF727_RS02140 Genome accession   NZ_CP062356
Coordinates   398765..399451 (+) Length   228 a.a.
NCBI ID   WP_001802022.1    Uniprot ID   A0A7U7EYP5
Organism   Staphylococcus aureus strain NAS_AN_203     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 393765..404451
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IF727_RS02105 (IF727_02105) yqeH 394292..395392 (+) 1101 WP_001280137.1 ribosome biogenesis GTPase YqeH -
  IF727_RS02110 (IF727_02110) aroE 395406..396212 (+) 807 WP_000666757.1 shikimate dehydrogenase -
  IF727_RS02115 (IF727_02115) yhbY 396216..396506 (+) 291 WP_240022442.1 ribosome assembly RNA-binding protein YhbY -
  IF727_RS02120 (IF727_02120) nadD 396509..397078 (+) 570 WP_000725167.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  IF727_RS02125 (IF727_02125) yqeK 397068..397652 (+) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  IF727_RS02130 (IF727_02130) rsfS 397653..398006 (+) 354 WP_001088020.1 ribosome silencing factor -
  IF727_RS02135 (IF727_02135) - 398009..398725 (+) 717 WP_000084830.1 class I SAM-dependent methyltransferase -
  IF727_RS02140 (IF727_02140) comEA 398765..399451 (+) 687 WP_001802022.1 ComEA family DNA-binding protein Machinery gene
  IF727_RS02145 (IF727_02145) - 399543..400004 (+) 462 WP_000439693.1 ComE operon protein 2 -
  IF727_RS02150 (IF727_02150) comEC 400009..402210 (+) 2202 WP_001557362.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  IF727_RS02155 (IF727_02155) holA 402267..403241 (+) 975 WP_001282563.1 DNA polymerase III subunit delta -
  IF727_RS02160 (IF727_02160) rpsT 403286..403537 (-) 252 WP_001274017.1 30S ribosomal protein S20 -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25900.65 Da        Isoelectric Point: 9.6751

>NTDB_id=488352 IF727_RS02140 WP_001802022.1 398765..399451(+) (comEA) [Staphylococcus aureus strain NAS_AN_203]
MVLLYQFLLRYKDFLTQWKLYIISAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENNSLSKLEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLDDADVSRINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHVKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTI

Nucleotide


Download         Length: 687 bp        

>NTDB_id=488352 IF727_RS02140 WP_001802022.1 398765..399451(+) (comEA) [Staphylococcus aureus strain NAS_AN_203]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAGTGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAATAGTTTGTCCAAATTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAAGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGATGATGCAGATGTAAGTCGAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGAAGTAAACAGTGTGCACGTAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACCGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTAGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGATATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7EYP5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus N315

100

100

1
  comEA Staphylococcus aureus MW2

97.368

100

0.974