Detailed information NTG0488149

Bioinformatically predicted

Overview

• Name: comGC
• Type: Machinery gene
• Locus tag: IF739_RS02380
• Genome accession: NZ_CP062346
• Coordinates: 449896..450207 (+)
• Length: 103 a.a.
• NCBI ID: WP_000472256.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain NAS_AN_261
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 444896..455207

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IF739_RS02350 (IF739_02335)	-	445679..445882 (+)	204	WP_000087561.1	YqgQ family protein	-
IF739_RS02355 (IF739_02340)	-	445879..446865 (+)	987	WP_000161315.1	ROK family glucokinase	-
IF739_RS02360 (IF739_02345)	-	446865..447194 (+)	330	WP_001018871.1	MTH1187 family thiamine-binding protein	-
IF739_RS02365 (IF739_02350)	-	447191..447814 (+)	624	WP_047213494.1	MBL fold metallo-hydrolase	-
IF739_RS02370 (IF739_02355)	comGA	447866..448840 (+)	975	WP_000697222.1	competence type IV pilus ATPase ComGA	Machinery gene
IF739_RS02375 (IF739_02360)	comGB	448812..449882 (+)	1071	Protein_436	competence type IV pilus assembly protein ComGB	-
IF739_RS02380 (IF739_02365)	comGC	449896..450207 (+)	312	WP_000472256.1	competence type IV pilus major pilin ComGC	Machinery gene
IF739_RS02385 (IF739_02370)	comGD	450185..450631 (+)	447	WP_072357807.1	competence type IV pilus minor pilin ComGD	Machinery gene
IF739_RS02390 (IF739_02375)	comGE	450618..450917 (+)	300	WP_000844415.1	hypothetical protein	Machinery gene
IF739_RS02395 (IF739_02380)	comGF	450835..451332 (+)	498	WP_001825340.1	competence type IV pilus minor pilin ComGF	Machinery gene
IF739_RS02400 (IF739_02385)	-	451429..451575 (+)	147	WP_001789879.1	hypothetical protein	-
IF739_RS02405 (IF739_02390)	-	451565..452089 (+)	525	WP_001015120.1	shikimate kinase	-
IF739_RS02410 (IF739_02395)	gcvT	452248..453339 (+)	1092	WP_000093354.1	glycine cleavage system aminomethyltransferase GcvT	-
IF739_RS02415 (IF739_02400)	gcvPA	453359..454705 (+)	1347	WP_000019687.1	aminomethyl-transferring glycine dehydrogenase subunit GcvPA	-

Sequence

Protein

• Length: 103 a.a.
• Molecular weight: 11315.36 Da
• Isoelectric Point: 8.5268

>NTDB_id=488149 IF739_RS02380 WP_000472256.1 449896..450207(+) (comGC) [Staphylococcus aureus strain NAS_AN_261]
MFKFLKKTQAFTLIEMLLVLLIISLLLILIIPNIAKQTAHIQSTGCNAQVKMVNSQIEAYALKHNRNPSSIEDLIADGFI
KEAQKTCKSGETITISNGEAVAN

Nucleotide

• Length: 312 bp

>NTDB_id=488149 IF739_RS02380 WP_000472256.1 449896..450207(+) (comGC) [Staphylococcus aureus strain NAS_AN_261]
ATGTTTAAATTTCTAAAGAAAACTCAAGCGTTTACATTGATAGAGATGCTATTAGTGTTATTAATCATCAGTTTATTATT
AATTTTAATCATTCCAAATATTGCTAAACAAACTGCTCACATACAATCAACAGGTTGTAATGCACAGGTAAAAATGGTTA
ATAGTCAAATTGAAGCGTATGCATTGAAACATAATAGAAATCCATCGTCTATTGAAGACTTAATTGCAGATGGTTTTATA
AAAGAAGCACAAAAGACATGTAAATCAGGAGAGACAATAACAATTAGTAATGGAGAAGCAGTTGCAAATTAG

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (6-30)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGC	Staphylococcus aureus MW2	100	100	1
comGC	Staphylococcus aureus N315	100	100	1
comGC/cglC	Streptococcus pneumoniae TIGR4	46.078	99.029	0.456
comGC/cglC	Streptococcus pneumoniae Rx1	46.078	99.029	0.456
comGC/cglC	Streptococcus pneumoniae D39	46.078	99.029	0.456
comGC/cglC	Streptococcus pneumoniae R6	46.078	99.029	0.456
comGC/cglC	Streptococcus mitis SK321	51.163	83.495	0.427
comGC/cglC	Streptococcus mitis NCTC 12261	51.163	83.495	0.427
comYC	Streptococcus gordonii str. Challis substr. CH1	42.857	95.146	0.408
comYC	Streptococcus suis isolate S10	50	75.728	0.379
comGC	Bacillus subtilis subsp. subtilis str. 168	41.758	88.35	0.369
comGC	Lactococcus lactis subsp. cremoris KW2	46.341	79.612	0.369