Detailed information NTG0487673

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: IF771_RS08155
• Genome accession: NZ_CP062320
• Coordinates: 1633351..1634394 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain NAS_OP_101
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1628351..1639394

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IF771_RS08125 (IF771_08120)	-	1628769..1630025 (-)	1257	WP_001795438.1	aminopeptidase	-
IF771_RS08130 (IF771_08125)	-	1630028..1630228 (-)	201	WP_000180461.1	DUF1128 family protein	-
IF771_RS08135 (IF771_08130)	-	1630375..1630839 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
IF771_RS08140 (IF771_08135)	-	1630846..1631121 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
IF771_RS08145 (IF771_08140)	-	1631399..1632616 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
IF771_RS08150 (IF771_08145)	vraR	1632732..1633361 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
IF771_RS08155 (IF771_08150)	vraS	1633351..1634394 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
IF771_RS08160 (IF771_08155)	liaF	1634391..1635092 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
IF771_RS08165 (IF771_08160)	-	1635107..1635493 (-)	387	WP_001110179.1	hypothetical protein	-
IF771_RS08170 (IF771_08165)	map	1635710..1636468 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
IF771_RS08175 (IF771_08170)	-	1636996..1637982 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
IF771_RS08180 (IF771_08175)	-	1638413..1638826 (-)	414	WP_001549145.1	hypothetical protein	-
IF771_RS08185 (IF771_08180)	-	1638855..1638965 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=487673 IF771_RS08155 WP_001017131.1 1633351..1634394(-) (vraS) [Staphylococcus aureus strain NAS_OP_101]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=487673 IF771_RS08155 WP_001017131.1 1633351..1634394(-) (vraS) [Staphylococcus aureus strain NAS_OP_101]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1