Detailed information NTG0480260

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: IBL27_RS07155
• Genome accession: NZ_CP061071
• Coordinates: 1461482..1463743 (+)
• Length: 753 a.a.
• NCBI ID: WP_002264699.1
• Uniprot ID: -
• Organism: Streptococcus mutans B04Sm5
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 1456482..1468743

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IBL27_RS07130 (IBL27_07130)	-	1457635..1458111 (-)	477	WP_002263564.1	ferrous iron transport protein A	-
IBL27_RS07135 (IBL27_07135)	-	1458304..1459038 (-)	735	WP_002264702.1	amino acid ABC transporter ATP-binding protein	-
IBL27_RS07140 (IBL27_07140)	-	1459038..1459724 (-)	687	WP_002263566.1	amino acid ABC transporter permease	-
IBL27_RS07145 (IBL27_07145)	-	1459938..1460168 (-)	231	WP_002263567.1	YkuJ family protein	-
IBL27_RS07150 (IBL27_07150)	argF	1460245..1461225 (-)	981	WP_002266430.1	ornithine carbamoyltransferase	-
IBL27_RS07155 (IBL27_07155)	clpE	1461482..1463743 (+)	2262	WP_002264699.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
IBL27_RS07160 (IBL27_07160)	-	1463854..1464309 (+)	456	WP_002263570.1	NUDIX hydrolase	-
IBL27_RS07165 (IBL27_07165)	-	1464376..1464678 (+)	303	WP_002263571.1	DUF1827 family protein	-
IBL27_RS07170 (IBL27_07170)	ileS	1465453..1468245 (-)	2793	WP_002266308.1	isoleucine--tRNA ligase	-

Sequence

Protein

• Length: 753 a.a.
• Molecular weight: 83761.91 Da
• Isoelectric Point: 5.0597

>NTDB_id=480260 IBL27_RS07155 WP_002264699.1 1461482..1463743(+) (clpE) [Streptococcus mutans B04Sm5]
MLCQNCKLNEATIHLYANVNGQQKQIDLCQNCYQIMKTDPENGPLNHLSQQNSSSINPFFDDFFGDLNNFRAFNNQDLPN
TPPTQAGGGNGNGGNNRRPGGPQQQASQKPNGLLEEFGINLTDIARKGEIDPVIGRDEEITRVIEILNRRTKNNPVLIGE
PGVGKTAVVEGLAQKIVDGDVPQKLHGKNVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRQRQDVILFIDEIHEIVGAGS
AGDGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVAETITILKGIQPKYEDYHHVKYTDE
AIEAAANLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKEIDHRLIEAENLKAQATRDEDYEKAAYFRDQIAKYKE
MQSAKLDKENTPVITEKNIEVIVEQKTNIPVGELKEKEQSQLIHLADDLKTRVIGQDAAVDKIAKAIRRNRVGLGTPNRP
IGSFLFVGPTGVGKTELSKQLAIELFGSEDSMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEKVRRNPYSLILLD
EVEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKSEANVGFGASREGRTNSVLGELGNFFSPEFMNR
FDGIIEFQALSKDNLLQIVSLMLDDVNQRLAVNAIHLDVTDKVKEKLVDLGYDPKMGARPLRRTIQEHIEDAITDFYLEH
PEQKELKAIMTSNGKIVIRASNKVETVTKATSD

Nucleotide

• Length: 2262 bp

>NTDB_id=480260 IBL27_RS07155 WP_002264699.1 1461482..1463743(+) (clpE) [Streptococcus mutans B04Sm5]
ATGCTCTGTCAAAATTGTAAATTAAATGAAGCGACTATTCATCTATATGCTAATGTTAATGGTCAGCAAAAGCAGATTGA
CCTTTGTCAAAATTGTTATCAAATTATGAAAACAGATCCTGAAAATGGACCTTTAAATCATCTTTCGCAACAAAATTCAT
CATCCATCAATCCTTTCTTTGATGATTTCTTTGGCGATTTGAATAATTTTCGTGCCTTTAATAATCAAGATCTGCCAAAC
ACACCGCCAACACAAGCTGGCGGCGGCAATGGCAACGGAGGCAATAATCGCCGTCCCGGTGGACCTCAGCAACAGGCCTC
CCAAAAGCCAAATGGGTTGCTTGAAGAGTTTGGTATTAATTTAACAGATATTGCGCGCAAGGGTGAAATTGATCCTGTTA
TTGGCCGTGATGAAGAAATCACAAGGGTTATCGAAATTCTCAACCGTCGCACAAAGAATAATCCTGTTCTTATTGGAGAA
CCGGGTGTCGGTAAAACTGCTGTTGTCGAAGGACTGGCGCAAAAAATTGTTGATGGTGATGTTCCACAAAAATTACATGG
AAAAAATGTCATTCGTCTGGACGTCGTCAGCCTTGTTCAAGGTACTGGTATTCGAGGCCAATTTGAAGAACGGATGCAAA
AATTAATGGAAGAAATCCGTCAACGTCAAGATGTTATTCTTTTCATTGATGAAATTCATGAAATTGTTGGTGCTGGTTCT
GCTGGCGATGGCAATATGGACGCCGGAAATATTTTAAAACCCGCTTTGGCACGCGGTGAGCTTCAACTTGTTGGTGCTAC
AACACTCAATGAATATCGGATTATTGAAAAAGATGCCGCTTTGGAACGTCGAATGCAACCCGTAAAAGTTGATGAACCTA
GTGTTGCAGAAACCATAACGATTCTTAAAGGTATTCAGCCCAAATATGAAGATTACCATCATGTAAAGTATACAGATGAA
GCGATTGAAGCTGCTGCAAATCTTTCAAATCGTTACATTCAGGATCGTTTTTTACCTGATAAGGCTATTGATCTTCTAGA
TGAAGCTGGCTCTAAAATGAATTTAACACTTAACTTTGTAGATCCTAAAGAAATTGATCACCGCTTGATTGAAGCCGAAA
ATCTAAAAGCTCAAGCAACCCGTGATGAAGATTATGAAAAAGCAGCTTACTTCCGTGATCAAATTGCCAAATACAAGGAA
ATGCAATCCGCTAAACTTGATAAGGAGAATACTCCTGTTATTACAGAAAAAAATATTGAAGTAATTGTCGAGCAAAAGAC
CAATATTCCTGTTGGTGAATTAAAAGAAAAGGAACAATCACAATTAATTCATCTCGCTGACGATCTTAAAACGCGTGTTA
TTGGACAGGATGCTGCTGTTGATAAAATTGCTAAAGCTATTCGCCGCAATCGTGTTGGACTAGGCACTCCAAATCGGCCA
ATTGGTTCTTTCCTTTTTGTCGGCCCTACTGGTGTTGGTAAAACGGAACTCTCTAAACAATTAGCTATTGAGCTTTTTGG
TTCTGAAGATAGTATGATTCGTTTCGATATGAGTGAATACATGGAAAAACATGCTGTGGCTAAACTTGTTGGTGCACCTC
CGGGATATGTCGGTTATGAAGAAGCTGGTCAGTTAACCGAAAAAGTTCGTCGCAACCCTTATTCATTGATCTTACTCGAT
GAAGTTGAAAAAGCTCACCCAGATGTCATGCATATGTTCTTACAAGTGCTTGATGATGGTCGTCTAACGGATGGGCAAGG
ACGCACTGTCAGCTTTAAGGATACTATTATTATCATGACCTCAAATGCTGGTACAGGGAAATCTGAAGCTAATGTTGGTT
TTGGTGCCAGTCGAGAAGGCCGTACTAATTCTGTTCTAGGCGAATTGGGTAACTTCTTTAGCCCTGAATTTATGAACCGT
TTTGATGGTATCATCGAATTTCAGGCTTTAAGTAAGGATAATCTTCTTCAAATTGTTTCTCTCATGCTGGATGACGTTAA
TCAACGTTTAGCTGTTAATGCTATTCACCTTGATGTAACTGATAAAGTTAAAGAAAAATTGGTTGATCTCGGTTATGATC
CTAAAATGGGAGCAAGACCGCTACGTCGTACTATCCAAGAACATATTGAAGATGCTATTACGGATTTCTACTTAGAGCAT
CCTGAACAAAAAGAACTAAAAGCTATTATGACAAGCAATGGCAAAATTGTTATCAGGGCTTCTAACAAAGTCGAGACGGT
TACCAAAGCAACTTCAGATTAA

Domains

Predicted by InterproScan.

• AAA lid domain (AAA_lid_9) (294-391)

• ATPase family associated with various cellular activities (AAA) (AAA) (156-275)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (650-721)

• AAA domain (Cdc48 subfamily) (AAA_2) (479-642)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	99.867	100	0.999
clpE	Streptococcus pneumoniae Rx1	82.62	99.336	0.821
clpE	Streptococcus pneumoniae D39	82.62	99.336	0.821
clpE	Streptococcus pneumoniae R6	82.62	99.336	0.821
clpE	Streptococcus pneumoniae TIGR4	82.62	99.336	0.821
clpC	Lactococcus lactis subsp. cremoris KW2	76.424	100	0.766
clpC	Bacillus subtilis subsp. subtilis str. 168	53.159	86.189	0.458
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	48	86.321	0.414
clpC	Streptococcus pneumoniae Rx1	49.355	82.337	0.406
clpC	Streptococcus pneumoniae D39	49.355	82.337	0.406
clpC	Streptococcus pneumoniae TIGR4	49.194	82.337	0.405
clpC	Streptococcus thermophilus LMD-9	47.764	83.134	0.397
clpC	Streptococcus thermophilus LMG 18311	47.444	83.134	0.394
clpC	Streptococcus mutans UA159	47.011	82.205	0.386