Detailed information NTG0479999

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: IAR39_RS02105
• Genome accession: NZ_CP061041
• Coordinates: 408141..409184 (-)
• Length: 347 a.a.
• NCBI ID: WP_002466111.1
• Uniprot ID: A0A5F0TYQ0
• Organism: Staphylococcus warneri strain WS479
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 403141..414184

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IAR39_RS02075 (IAR39_02075)	-	403639..404880 (-)	1242	WP_058710066.1	aminopeptidase	-
IAR39_RS02080 (IAR39_02080)	-	404893..405096 (-)	204	WP_002466135.1	DUF1128 domain-containing protein	-
IAR39_RS02085 (IAR39_02085)	-	405243..405707 (+)	465	WP_002466141.1	low molecular weight protein-tyrosine-phosphatase	-
IAR39_RS02090 (IAR39_02090)	-	405714..405998 (+)	285	WP_002466132.1	YtxH domain-containing protein	-
IAR39_RS02095 (IAR39_02095)	-	406228..407463 (+)	1236	WP_187835303.1	YihY/virulence factor BrkB family protein	-
IAR39_RS02100 (IAR39_02100)	vraR	407522..408151 (-)	630	WP_058710065.1	response regulator transcription factor	Regulator
IAR39_RS02105 (IAR39_02105)	vraS	408141..409184 (-)	1044	WP_002466111.1	sensor histidine kinase	Regulator
IAR39_RS02110 (IAR39_02110)	liaF	409181..409882 (-)	702	WP_015364858.1	cell wall-active antibiotics response protein LiaF	-
IAR39_RS02115 (IAR39_02115)	-	409897..410283 (-)	387	WP_002466133.1	DUF2543 family protein	-
IAR39_RS02120 (IAR39_02120)	map	410427..411182 (-)	756	WP_002466104.1	type I methionyl aminopeptidase	-
IAR39_RS02125 (IAR39_02125)	-	411349..412335 (+)	987	WP_015364857.1	aromatic acid exporter family protein	-
IAR39_RS02130 (IAR39_02130)	-	412403..413128 (-)	726	WP_023373124.1	type 1 glutamine amidotransferase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40087.57 Da
• Isoelectric Point: 6.2449

>NTDB_id=479999 IAR39_RS02105 WP_002466111.1 408141..409184(-) (vraS) [Staphylococcus warneri strain WS479]
MNHYIRAIGSMLILIYSMLTAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNIIVILLCIIVGSVLAYKINQQNDWIKT
QIERSIEGETVGINDQNIELYSETLEIYHTLVPLNQELHRLRMKTQNLTNENYNMNDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETQLEPPLDQQIPVLEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QEFKVPKGIEDHLFRITQEAISNTLRHSNGTRVTVELFNKQDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYGD

Nucleotide

• Length: 1044 bp

>NTDB_id=479999 IAR39_RS02105 WP_002466111.1 408141..409184(-) (vraS) [Staphylococcus warneri strain WS479]
ATGAATCACTATATAAGAGCTATTGGGTCAATGCTGATATTGATATATAGTATGTTAACGGCGTTCTTATTTATTGATAA
AGTTTTTGTCAACATCATTTACTTTCAAGGAATGTTTTATACACAAATTTTCGGTATTCCAGTGTTCTTATTTTTAAATA
TTATAGTTATATTATTATGTATTATAGTTGGATCAGTTCTAGCATATAAAATTAATCAACAGAATGATTGGATTAAAACT
CAAATTGAGCGATCAATTGAAGGGGAAACTGTTGGAATTAATGATCAAAATATTGAATTGTATAGCGAGACGTTAGAAAT
ATATCATACACTTGTCCCGTTAAATCAAGAGTTACATCGATTAAGAATGAAAACACAAAATTTAACTAACGAAAATTACA
ATATGAATGATGTTAAAGTTAAAAAGATTATTGAAGATGAGCGACAACGCTTAGCTAGAGAATTACATGATTCTGTAAGC
CAACAATTATTCGCTGCGAGTATGATGTTATCTGCAATAAAAGAAACACAGTTAGAACCACCATTAGATCAACAAATACC
CGTACTTGAAAAGATGGTTCAAGATTCACAACTAGAGATGAGAGCATTGTTACTTCATTTAAGACCATTAGGATTAAAAG
ATAAATCATTAGGTGAAGGTATTAAAGATTTAGTCATTGACCTTCAAAAGAAAGTACCAATGAAAGTAGTGCATGAAATT
CAAGAATTTAAAGTGCCAAAAGGAATTGAGGATCATTTATTCAGAATTACACAAGAAGCAATTTCAAATACATTGAGACA
TTCTAATGGCACAAGAGTAACGGTTGAATTATTTAATAAGCAAGATTATCTGCTTTTACGTATACAAGATAATGGCAAAG
GTTTTAATGTAGATGAGAAACTTGAACAAAGTTATGGATTAAAGAATATGCGTGAACGTGCACTAGAAATTGGTGCTACC
TTCCATATCGTATCGTTACCAGACTCTGGTACACGTATTGAAGTTAAAGCACCATTAAACAAGGAGGATTCGTATGGCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A5F0TYQ0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	94.813	100	0.948