Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Machinery gene
Locus tag   R2846_RS00720 Genome accession   NC_017452
Coordinates   141583..142380 (+) Length   265 a.a.
NCBI ID   WP_013527435.1    Uniprot ID   -
Organism   Haemophilus influenzae R2846     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 136583..147380
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R2846_RS00700 (R2846_0137) recR 136752..137354 (-) 603 WP_005626527.1 recombination mediator RecR -
  R2846_RS00705 (R2846_0138) - 137487..137816 (-) 330 WP_005629464.1 YbaB/EbfC family nucleoid-associated protein -
  R2846_RS00710 (R2846_0139) - 137969..138814 (-) 846 WP_005686902.1 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ -
  R2846_RS00715 (R2846_0140) - 138890..141484 (-) 2595 WP_014550411.1 penicillin-binding protein 1A -
  R2846_RS00720 (R2846_0141) comA 141583..142380 (+) 798 WP_013527435.1 pilus assembly protein PilM Machinery gene
  R2846_RS00725 (R2846_0142) comB 142381..142887 (+) 507 WP_014550412.1 competence protein ComB Machinery gene
  R2846_RS00730 (R2846_0143) comC 142884..143405 (+) 522 WP_005662592.1 competence protein ComC Machinery gene
  R2846_RS00735 (R2846_0144) comD 143402..143815 (+) 414 WP_014550413.1 pilus assembly protein PilP Machinery gene
  R2846_RS00740 (R2846_0145) comE 143825..145162 (+) 1338 WP_014550414.1 type IV pilus secretin PilQ family protein Machinery gene
  R2846_RS00745 (R2846_0146) - 145175..145861 (+) 687 WP_014550415.1 ComF family protein -
  R2846_RS00750 (R2846_0147) nfuA 145937..146533 (+) 597 WP_005656459.1 Fe-S biogenesis protein NfuA -

Sequence

Protein


Download         Length: 265 a.a.        Molecular weight: 31571.97 Da        Isoelectric Point: 6.2348

>NTDB_id=47284 R2846_RS00720 WP_013527435.1 141583..142380(+) (comA) [Haemophilus influenzae R2846]
MQFSLKNYRTLQIGIHRKQSYFDFVWFDDLEQPQSYQIFVNDRYFKNRFLQQLKTQYQGKTFPLQFVASIPAHLTWSKVL
MLPQVLNAQECHQQCKFVIEKELPIFLEELWFDYRSTPLKQGFRLEVTAIRKSTAQTYLQDFQPFKINVLDVASNAVLRA
FQYLLNEQVRSENTLFLFQEDDYCLAICERSQQSQILQSHENLTALYEQFTERFEGQLEQVFVYQIPSSHTPLLENWQRV
ETELPFIALGNALWQKDLHQQKVGG

Nucleotide


Download         Length: 798 bp        

>NTDB_id=47284 R2846_RS00720 WP_013527435.1 141583..142380(+) (comA) [Haemophilus influenzae R2846]
ATGCAATTCTCCCTGAAAAATTACCGCACTTTACAAATCGGCATTCATCGTAAGCAGAGTTATTTTGATTTTGTGTGGTT
TGATGATCTCGAACAGCCACAAAGTTATCAAATCTTTGTTAATGATCGTTATTTTAAAAATCGTTTTTTACAACAGCTAA
AAACACAATATCAAGGGAAAACCTTTCCTTTGCAGTTTGTAGCAAGCATTCCCGCTCACTTAACTTGGTCGAAAGTATTA
ATGTTGCCACAAGTGTTAAATGCGCAAGAATGTCATCAACAATGTAAATTTGTGATTGAGAAAGAGCTGCCTATTTTTTT
AGAAGAATTGTGGTTTGATTATCGTTCTACCCCGTTAAAGCAAGGTTTTCGATTAGAGGTTACTGCAATTCGTAAAAGTA
CTGCTCAAACTTATTTGCAAGATTTTCAGCCATTTAAAATTAATGTATTGGATGTTGCATCAAATGCTGTTTTGCGTGCA
TTTCAATATTTGTTGAATGAACAAGTGCGGTCAGAAAATACCTTATTTTTATTTCAAGAAGATGACTATTGCTTGGCGAT
TTGTGAAAGATCTCAGCAATCACAAATTTTACAATCTCACGAAAATTTGACCGCACTTTATGAACAATTTACCGAACGTT
TTGAAGGACAACTTGAACAAGTTTTTGTTTATCAAATTCCCTCAAGTCATACACCATTACTAGAAAATTGGCAGCGAGTA
GAAACAGAACTCCCTTTTATTGCACTTGGCAACGCGCTATGGCAAAAAGATTTACATCAACAAAAAGTGGGTGGTTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Haemophilus influenzae Rd KW20

98.491

100

0.985
  comA Haemophilus influenzae 86-028NP

96.981

100

0.97

Multiple sequence alignment