Detailed information    

insolico Bioinformatically predicted

Overview

Name   rexB   Type   Machinery gene
Locus tag   M1GAS476_RS03095 Genome accession   NC_020540
Coordinates   611268..614483 (+) Length   1071 a.a.
NCBI ID   WP_011285475.1    Uniprot ID   -
Organism   Streptococcus pyogenes M1 476     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 606268..619483
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M1GAS476_RS03070 (M1GAS476_0646) - 607515..607892 (+) 378 WP_002993028.1 OsmC family protein -
  M1GAS476_RS03075 (M1GAS476_0647) - 607885..608271 (+) 387 WP_002990406.1 YbgA family protein -
  M1GAS476_RS03080 (M1GAS476_0648) - 608344..609420 (+) 1077 WP_010922123.1 FtsX-like permease family protein -
  M1GAS476_RS03085 (M1GAS476_0649) - 609430..610098 (+) 669 WP_011285473.1 ABC transporter ATP-binding protein -
  M1GAS476_RS03090 (M1GAS476_0650) - 610200..611117 (-) 918 WP_011285474.1 neutral zinc metallopeptidase -
  M1GAS476_RS03095 (M1GAS476_0651) rexB 611268..614483 (+) 3216 WP_011285475.1 ATP-dependent nuclease subunit B Machinery gene
  M1GAS476_RS03100 (M1GAS476_0652) rexA 614480..618112 (+) 3633 WP_032459868.1 helicase-exonuclease AddAB subunit AddA Machinery gene
  M1GAS476_RS03105 (M1GAS476_0654) - 618252..619064 (+) 813 WP_002990394.1 transporter substrate-binding domain-containing protein -
  M1GAS476_RS03110 rpsU 619205..619381 (+) 177 WP_000048058.1 30S ribosomal protein S21 -

Sequence

Protein


Download         Length: 1071 a.a.        Molecular weight: 124158.06 Da        Isoelectric Point: 6.8147

>NTDB_id=47022 M1GAS476_RS03095 WP_011285475.1 611268..614483(+) (rexB) [Streptococcus pyogenes M1 476]
MKLIYTEMSYSMTEILVNEARKAADQGYRVFYIAPNSLSFEKEREVLTLLPERGTFSIIVTRFVQMSRYFTVESSPSKQH
LDDTTLAMIFYRALMQLKPEDLPSYGRLQNNSVFIEQLVELYKELKNAQLSVHDLTGLDHPKKQEDLIKIIELAETIMIQ
QDYNQDSPLQSFARAIKLGLLNNQLSKTVVVIDGFSRFSAEEDYLLSLLNNNCQEVIIGSYVSQKAYQKSFIKGNIYEAS
LHFLQDLAQKYHIKPVFATSNQVFKPAFSRLTQLFEATHDFSQVDWQLQKSDLDHFSLWQCHHQKEEIEHVAKSIRQKLY
EGYRYKDILVLLGDMDAYQLQIGPIFDKFEIPYYLGKAEPMAAHPLVQFIESLERSQRYNWRREDILNMLKSGLFGCFDD
SDIDRFEEYTQFADIKGFTKFSKPFTINSSRQYPLDFLNEMRQDIVLPLQELFKSQKQLGASLVDKLILFLKKIRLAENM
QGLAQSQLEVEKNEEVWKRFTDILTSFHHIFGQEKLRLSDCLALIKTGMKSAQYRVVPATLDVVTIKSYDLVQPHSKPFV
YAIGLTQSHFPKQIHHSGLLSDQERARINEIRNYRHFDIASAENSKKNHQTALSLFNAATKELVLSVSTVINETFDDLSP
YLKELINFGLPLLDKGKNYLSYDNSDIGNYKALLSQIIAINRQDLIEMSDQDKMFWTVVLRYLRKQLRKQQLELPTSDYR
LSTKPLSKEVIEVCFPKGIPLKLSATALTVFYNNQYNYFLKYVLNLNKTESIHPDSRIHGQYLHRVFERLMKDHTQEPFD
NKLKQAIYHTNQESFFQQVYQDNAEAEYSLAILEDIVRSTAPILQLNQNIQVIDQEKNFQLDMGNEILVHGIIDRIDQLS
DGSLGIVDYKSSANQFDIGTFYNGLSPQLMTYLAALKQIAPHDINQLFGAMYLHLQDPKLDLVTFKQIDNTLVESIYKAL
TYKGIFSEVEKEHLSTGAYQTKNALYSNDELETLLNYNKYLYLKAAKHIKKGHFLINPYTSDGKTVQGDQLKAITRFEAD
LDMGQARRLVTLPAKEKKECFLTLMRKESHL

Nucleotide


Download         Length: 3216 bp        

>NTDB_id=47022 M1GAS476_RS03095 WP_011285475.1 611268..614483(+) (rexB) [Streptococcus pyogenes M1 476]
ATGAAATTAATTTACACAGAGATGAGTTACTCGATGACAGAGATTTTGGTGAATGAAGCACGAAAAGCTGCTGACCAAGG
TTATCGAGTGTTCTATATTGCTCCAAATTCTCTTTCATTTGAAAAGGAAAGGGAAGTCTTAACCTTATTGCCTGAACGAG
GGACTTTTTCGATAATAGTCACCCGGTTCGTTCAAATGTCAAGGTATTTTACAGTTGAGAGCTCTCCTTCTAAGCAACAT
CTAGATGACACGACTTTGGCTATGATTTTTTATCGGGCCTTGATGCAATTAAAACCAGAAGATTTGCCGAGTTATGGTCG
TTTGCAAAATAATTCGGTTTTTATTGAACAACTAGTTGAGTTATATAAAGAATTAAAAAACGCACAATTAAGCGTACATG
ATTTAACAGGGTTAGACCATCCTAAAAAACAAGAAGATCTTATTAAAATTATTGAGCTTGCAGAGACGATCATGATTCAG
CAAGATTATAATCAAGATAGTCCTCTACAATCTTTTGCAAGAGCAATTAAGTTAGGACTTTTAAATAACCAACTATCAAA
AACAGTTGTTGTTATTGATGGTTTTTCACGTTTTTCAGCTGAAGAGGATTATTTATTATCACTTTTAAATAACAACTGTC
AAGAGGTCATCATTGGCAGTTATGTGAGTCAAAAAGCTTATCAAAAATCTTTTATTAAGGGAAATATCTATGAGGCTAGC
CTTCATTTTTTGCAAGATTTGGCTCAAAAATACCATATCAAGCCGGTATTTGCGACCTCTAATCAAGTGTTTAAACCAGC
CTTTTCACGGCTAACACAATTATTTGAAGCAACTCATGATTTTTCACAAGTAGACTGGCAACTCCAAAAGAGTGATCTTG
ATCACTTTAGCCTTTGGCAATGTCATCATCAAAAAGAGGAAATTGAACATGTAGCAAAATCCATTCGGCAAAAGCTATAT
GAAGGTTACCGTTATAAGGATATCTTAGTGTTGCTAGGAGATATGGATGCTTATCAATTACAAATTGGGCCTATCTTTGA
TAAGTTTGAAATCCCCTACTATTTAGGAAAAGCAGAGCCTATGGCTGCCCATCCATTAGTCCAATTTATAGAATCGCTCG
AACGAAGTCAGCGCTATAATTGGCGTCGTGAAGACATTTTAAACATGTTAAAATCAGGACTTTTTGGTTGTTTTGATGAT
AGTGATATTGATCGCTTTGAGGAATATACTCAGTTTGCAGATATTAAAGGATTTACTAAATTTTCAAAGCCTTTTACCAT
TAACTCTTCTAGGCAGTATCCTCTTGACTTTTTAAATGAAATGAGACAAGACATCGTTTTACCTTTGCAAGAATTGTTTA
AGAGTCAAAAACAACTTGGTGCTTCACTTGTTGACAAATTAATACTTTTTTTAAAAAAGATTAGATTAGCTGAGAATATG
CAAGGTTTAGCACAGTCCCAATTAGAGGTGGAAAAAAACGAAGAAGTTTGGAAAAGGTTTACAGATATTTTGACTTCTTT
TCATCATATCTTTGGCCAAGAAAAATTACGGCTATCAGATTGCCTTGCTTTAATTAAAACGGGAATGAAATCAGCTCAGT
ATCGTGTTGTTCCAGCGACATTAGATGTTGTCACTATTAAATCTTATGACCTTGTTCAACCACATTCAAAACCTTTCGTT
TATGCAATTGGTCTAACTCAATCACATTTTCCTAAGCAAATTCACCATTCAGGACTACTTTCTGATCAAGAGCGTGCTAG
AATTAATGAAATAAGAAATTATCGTCATTTTGATATTGCTAGTGCCGAAAATAGTAAAAAAAACCATCAAACTGCGTTAT
CTCTGTTTAATGCTGCTACTAAGGAGTTAGTTCTTAGTGTTTCAACGGTAATCAACGAGACATTCGATGATCTATCTCCT
TATCTTAAAGAATTAATAAACTTTGGGTTACCTCTTTTGGATAAAGGCAAAAACTATCTATCTTATGATAATAGCGATAT
TGGTAACTATAAAGCTCTCTTGTCACAAATTATTGCTATTAACCGACAAGATCTTATAGAAATGTCAGATCAAGATAAGA
TGTTTTGGACTGTTGTCTTACGTTATCTCAGGAAACAGTTAAGAAAGCAACAGCTAGAGCTACCTACTTCAGATTATCGT
TTATCAACAAAGCCTTTGTCTAAAGAAGTTATCGAGGTATGTTTTCCAAAGGGAATCCCTTTAAAGCTATCTGCAACTGC
TTTAACCGTTTTTTATAATAATCAGTACAACTATTTTTTGAAATATGTTTTGAATTTAAACAAAACAGAATCCATTCATC
CAGATTCCAGAATTCATGGTCAATACTTGCATCGTGTCTTTGAGCGGTTAATGAAAGATCACACGCAAGAACCGTTTGAT
AATAAGTTAAAACAAGCAATCTACCATACCAATCAAGAAAGTTTTTTTCAGCAGGTTTACCAAGATAATGCCGAGGCTGA
GTACAGTTTAGCTATACTAGAAGATATTGTTAGATCAACAGCACCTATCTTGCAACTTAACCAAAACATACAGGTCATTG
ATCAAGAAAAGAACTTTCAGCTGGATATGGGAAATGAGATATTAGTCCACGGGATCATTGATCGTATTGACCAGCTGAGC
GACGGTAGCTTGGGCATTGTTGACTATAAATCAAGCGCGAATCAATTTGATATTGGGACCTTTTATAATGGGTTGAGTCC
ACAACTAATGACTTACCTCGCAGCCTTAAAACAGATTGCACCGCACGATATAAACCAATTATTTGGGGCTATGTACCTTC
ATTTGCAAGATCCTAAATTGGATCTAGTAACATTTAAACAAATTGATAACACATTAGTGGAGAGTATCTATAAAGCGTTG
ACCTATAAAGGTATTTTTTCAGAAGTCGAAAAAGAGCATCTATCTACTGGTGCTTACCAAACCAAAAATGCTCTTTATTC
CAATGACGAATTGGAAACACTTTTAAATTATAACAAGTACCTCTATCTTAAAGCTGCTAAACACATTAAAAAGGGACATT
TTTTGATTAATCCTTATACAAGCGATGGTAAGACAGTTCAAGGAGATCAATTAAAAGCCATTACCCGTTTTGAAGCAGAT
CTTGACATGGGACAGGCAAGGCGACTAGTGACTCTCCCTGCTAAGGAGAAAAAAGAGTGCTTTTTAACATTAATGAGAAA
GGAGAGCCACTTGTGA

Domains

Predicted by InterProScan.

PD-(D/E)XK nuclease superfamily (PDDEXK_1)

(743-1020)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  rexB Streptococcus pneumoniae R6

41.341

100

0.415

Multiple sequence alignment