Detailed information NTG0045991

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: KSO_RS18595
• Genome accession: NC_020272
• Coordinates: 3819343..3820425 (-)
• Length: 360 a.a.
• NCBI ID: WP_003156401.1
• Uniprot ID: A0AAI8HS26
• Organism: Bacillus amyloliquefaciens IT-45
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 3814343..3825425

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KSO_RS18570 (KSO_018935)	cysE	3814442..3815095 (-)	654	WP_003156410.1	serine O-acetyltransferase	-
KSO_RS18575 (KSO_018940)	gltX	3815406..3816857 (-)	1452	WP_015388783.1	glutamate--tRNA ligase	-
KSO_RS18580 (KSO_018945)	ispF	3816949..3817425 (-)	477	WP_003156407.1	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	-
KSO_RS18585 (KSO_018950)	ispD	3817418..3818116 (-)	699	WP_003156405.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-
KSO_RS18590 (KSO_018955)	-	3818129..3819229 (-)	1101	WP_003156403.1	PIN/TRAM domain-containing protein	-
KSO_RS18595 (KSO_018960)	disA	3819343..3820425 (-)	1083	WP_003156401.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
KSO_RS18600 (KSO_018965)	radA/sms	3820429..3821808 (-)	1380	WP_015388784.1	DNA repair protein RadA	Machinery gene
KSO_RS18605 (KSO_018970)	clpC	3821902..3824334 (-)	2433	WP_007410388.1	ATP-dependent protease ATP-binding subunit ClpC	Regulator
KSO_RS18610 (KSO_018975)	-	3824331..3825422 (-)	1092	WP_003156398.1	protein arginine kinase	-

Sequence

Protein

• Length: 360 a.a.
• Molecular weight: 40671.21 Da
• Isoelectric Point: 5.5321

>NTDB_id=45991 KSO_RS18595 WP_003156401.1 3819343..3820425(-) (disA) [Bacillus amyloliquefaciens IT-45]
MEKEKKGAKQELDLSAILQFVAPGTPLRAGIENVLRANTGGLIVVGYNDKVKQVVDGGFHINTSFAPAHLYELAKMDGAI
ILSDSGQKILYANTQLMPEATISSSETGMRHRTAERVAKQTGCLVIAISERRNVITLYQDSMKYTLKDIGFILTKANQAI
QTLEKYKTILDKTITALNALEFEELVTFSDVLSVMHRYEMVLRIKNEINMYIKELGTEGHLIRLQVIELITDMEEEAALF
IKDYVKEKIKDPFVLLKELQDMSSYDLLDDSILFKLLGYPASTNLDDYVLPRGYRLLNKIPRLPMPIVENVVEAFGFLPS
ITEATVEELDDVEGIGEVRAQKIKKGLKRLQEKHYIDRQL

Nucleotide

• Length: 1083 bp

>NTDB_id=45991 KSO_RS18595 WP_003156401.1 3819343..3820425(-) (disA) [Bacillus amyloliquefaciens IT-45]
ATGGAAAAAGAGAAAAAAGGGGCGAAACAAGAGCTTGACCTGTCTGCAATTCTGCAGTTCGTTGCACCGGGCACCCCGCT
CAGAGCCGGGATAGAGAATGTACTTCGGGCAAATACAGGCGGCCTGATTGTTGTCGGATACAATGATAAGGTAAAGCAAG
TCGTGGATGGCGGTTTTCATATTAATACATCATTTGCGCCCGCTCACTTATACGAGCTGGCCAAAATGGACGGTGCCATT
ATTTTAAGTGATTCCGGCCAGAAAATTCTTTATGCGAATACGCAGCTTATGCCGGAGGCGACCATTTCTTCTTCAGAAAC
GGGAATGAGGCACCGTACGGCGGAACGGGTGGCGAAGCAGACCGGCTGTCTCGTCATCGCCATTTCTGAGCGCAGAAATG
TCATTACGTTATATCAGGACAGCATGAAGTACACACTAAAGGACATAGGTTTTATTTTAACAAAGGCAAATCAGGCCATT
CAAACGCTCGAGAAGTATAAAACCATTTTAGACAAAACAATTACGGCTCTAAACGCGTTAGAGTTTGAGGAGCTTGTGAC
ATTCAGTGACGTGCTGTCTGTCATGCATCGGTATGAAATGGTGCTCCGAATAAAAAATGAAATCAATATGTATATTAAAG
AACTCGGAACGGAAGGCCACTTAATCCGTCTGCAGGTGATTGAACTGATTACGGACATGGAAGAAGAGGCGGCACTTTTC
ATCAAAGACTATGTCAAAGAAAAAATCAAAGATCCGTTCGTGCTGTTAAAAGAGCTCCAGGATATGTCCAGCTATGATCT
GCTGGATGATTCCATTCTGTTTAAACTGCTTGGATACCCGGCTTCTACGAATCTTGATGATTATGTGCTCCCGAGAGGCT
ACAGGCTGCTGAACAAAATTCCGCGTCTGCCGATGCCGATTGTTGAAAATGTGGTTGAGGCGTTCGGATTTTTGCCAAGC
ATAACGGAAGCCACTGTAGAAGAGCTTGATGATGTCGAGGGTATCGGCGAAGTGCGCGCCCAAAAAATCAAAAAAGGCTT
AAAACGCCTTCAGGAAAAACACTATATAGATAGACAGCTTTAA

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (29-141)

• DisA bacterial checkpoint controller linker region (DisA-linker) (146-284)

3D structure

• AlphaFold DB: A0AAI8HS26

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	94.444	100	0.944