Detailed information NTG0452830

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: I6H76_RS06965
• Genome accession: NZ_CP065994
• Coordinates: 1362502..1364649 (-)
• Length: 715 a.a.
• NCBI ID: WP_043878344.1
• Uniprot ID: -
• Organism: Streptococcus infantarius strain FDAARGOS_1019
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1357502..1369649

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6H76_RS06940 (I6H76_06940)	-	1358148..1358918 (+)	771	WP_006531858.1	TatD family hydrolase	-
I6H76_RS06945 (I6H76_06945)	rnmV	1358890..1359480 (+)	591	WP_006531859.1	ribonuclease M5	-
I6H76_RS06950 (I6H76_06950)	-	1359477..1360001 (+)	525	WP_043878343.1	DUF1697 domain-containing protein	-
I6H76_RS06955 (I6H76_06955)	rsmA	1360090..1360962 (+)	873	WP_006531861.1	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	-
I6H76_RS06960 (I6H76_06960)	-	1361096..1362490 (-)	1395	WP_006531862.1	bacteriocin secretion accessory protein	-
I6H76_RS06965 (I6H76_06965)	comA/nlmT	1362502..1364649 (-)	2148	WP_043878344.1	peptide cleavage/export ABC transporter	Regulator
I6H76_RS06970 (I6H76_06970)	-	1364924..1365181 (+)	258	WP_006531864.1	bacteriocin class II family protein	-
I6H76_RS06975 (I6H76_06975)	-	1365199..1365393 (+)	195	WP_043878345.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
I6H76_RS06980 (I6H76_06980)	cipB	1365589..1365816 (+)	228	WP_006531867.1	Blp family class II bacteriocin	Regulator
I6H76_RS06985 (I6H76_06985)	-	1365818..1366006 (+)	189	WP_115283782.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
I6H76_RS06990 (I6H76_06990)	-	1366475..1366633 (+)	159	WP_006531869.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
I6H76_RS06995 (I6H76_06995)	-	1366661..1366816 (+)	156	WP_006531870.1	bacteriocin	-
I6H76_RS07000 (I6H76_07000)	-	1366856..1367530 (+)	675	WP_006531871.1	CPBP family intramembrane glutamic endopeptidase	-
I6H76_RS07005 (I6H76_07005)	-	1367871..1368173 (+)	303	WP_006531872.1	hypothetical protein	-
I6H76_RS07010 (I6H76_07010)	-	1368252..1368455 (+)	204	WP_081442276.1	garvicin Q family class II bacteriocin	-
I6H76_RS07015 (I6H76_07015)	-	1368467..1368769 (+)	303	WP_006531874.1	bacteriocin immunity protein	-
I6H76_RS07020 (I6H76_07020)	cipB	1368927..1369160 (+)	234	WP_006531875.1	Blp family class II bacteriocin	Regulator
I6H76_RS07025 (I6H76_07025)	-	1369180..1369368 (+)	189	WP_006531876.1	class IIb bacteriocin, lactobin A/cerein 7B family	-

Sequence

Protein

• Length: 715 a.a.
• Molecular weight: 80171.07 Da
• Isoelectric Point: 7.4929

>NTDB_id=452830 I6H76_RS06965 WP_043878344.1 1362502..1364649(-) (comA/nlmT) [Streptococcus infantarius strain FDAARGOS_1019]
MRRYKYVSQIDLRDCGVAALASVAKHYGSDFSLAHLRELAKTTKEGTTALGIVEAAKAIGFETRAIQANMELFDMADIPY
PFIVHVNKEGKLQHYYVVYKAKKNHLIIGDPDPSVKVTKMPKERFKKEWTGVAIFLAPAPHYQPHKDKKNGLTSFLPIIF
KQKALLTYIILASLLVTLINIVGSYYLQGILDDYIPNQLQSTLGIVSVGLIVTYIMQQIMSFSQNYLLVVLSQRLTIDVI
LSYIRHIFELPMSFFATRRTGEVISRFTDANSIIDALASTILSLFLDVSILFIVGSVLILQNTNLFFITLIALPIYAIII
LAFMKPFERMNHDVMQANSMVSSAIIEDINGIETIKSLTSEEVRYQNIDREFVDYLDKSFTLSKYEAVQTSLKQGAQLIL
NVAILWYGSRLVMAGNISVGQLITYNTLLSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVSSEFDSKQLLNDSHFLQG
DIVFDDVSYKYGFGRDTLSHVNLHIKKGEKISLVGISGSGKTTLAKMIVNFYTPNHGQITLGGYDLKTIDKKAIRQYINY
LPQQSYVFSGTILENLTLGAPDNITQEEILKACEIAEIRADIELMPLAYHTELSDGAGLSGGQKQRLALARALLTQAPVL
ILDEATSGLDVLTEKRVIKNLLSLTDKTIIFVAHRLSIAEQSDRVIVLDKGHVIEEGHHKQLIQNQGFYAQLFHE

Nucleotide

• Length: 2148 bp

>NTDB_id=452830 I6H76_RS06965 WP_043878344.1 1362502..1364649(-) (comA/nlmT) [Streptococcus infantarius strain FDAARGOS_1019]
ATGAGGAGATACAAGTATGTTAGTCAGATTGATTTGCGAGATTGTGGTGTGGCAGCTTTGGCATCAGTTGCCAAGCATTA
TGGATCTGATTTCTCACTGGCACACCTAAGGGAATTAGCTAAAACAACTAAGGAAGGGACGACAGCGTTAGGGATAGTCG
AGGCAGCTAAAGCCATTGGCTTTGAAACACGCGCCATTCAAGCTAACATGGAACTGTTTGATATGGCCGATATTCCCTAT
CCTTTTATTGTTCATGTTAACAAAGAAGGCAAACTGCAGCACTATTATGTCGTTTACAAAGCTAAGAAAAACCACCTTAT
CATCGGTGATCCAGACCCCAGTGTCAAAGTGACCAAAATGCCCAAGGAGCGCTTTAAAAAGGAATGGACAGGTGTCGCCA
TTTTCTTAGCACCTGCTCCGCATTATCAACCGCATAAAGATAAGAAAAATGGCTTAACAAGCTTTTTACCAATTATTTTC
AAACAAAAGGCACTGCTAACTTATATCATTCTGGCAAGTTTGCTCGTGACCTTGATTAACATTGTTGGGTCTTACTATTT
GCAAGGAATCTTAGACGATTATATTCCTAATCAATTGCAATCCACTCTTGGCATTGTCTCGGTTGGGTTGATTGTAACCT
ACATAATGCAACAAATCATGAGCTTTTCACAAAATTATTTACTTGTTGTGCTGAGCCAACGGTTAACAATTGACGTGATT
TTGTCTTATATTCGTCACATTTTTGAATTGCCCATGTCTTTTTTTGCCACAAGGCGGACAGGTGAAGTGATCTCACGTTT
CACCGATGCTAACTCGATTATTGATGCACTGGCATCAACGATTCTCTCTTTATTTTTAGATGTGAGTATTTTGTTTATTG
TCGGAAGTGTCTTAATTCTGCAAAATACCAATCTCTTTTTCATCACCTTAATAGCATTGCCTATCTATGCTATTATTATT
TTGGCTTTTATGAAGCCTTTTGAGCGAATGAATCACGATGTCATGCAAGCCAATTCTATGGTTAGCTCTGCGATTATCGA
AGATATCAATGGTATTGAAACGATTAAATCTTTGACTAGTGAGGAAGTCCGTTATCAAAATATTGACCGTGAATTTGTGG
ATTATTTGGATAAAAGTTTTACGCTTAGTAAGTATGAAGCTGTGCAAACGTCGTTAAAACAGGGAGCACAGCTAATTTTA
AACGTCGCCATTCTCTGGTATGGTTCACGTTTAGTCATGGCTGGGAACATTTCAGTAGGACAATTGATTACTTACAATAC
GCTTCTGTCGTACTTTACAACGCCAATGGAAAATATTATCAATCTGCAAACCAAACTACAATCTGCCAAAGTAGCTAATA
ATCGTCTCAACGAAGTTTACTTAGTGTCATCTGAATTTGATAGCAAACAACTCTTAAATGACAGCCATTTTCTACAAGGA
GATATTGTTTTTGATGATGTTTCTTATAAATATGGTTTTGGTCGTGACACGCTGAGTCATGTGAATTTACACATTAAGAA
AGGTGAAAAAATTAGCCTAGTTGGTATCAGCGGCTCTGGTAAGACAACCTTAGCTAAAATGATTGTCAATTTTTACACAC
CTAACCATGGACAGATTACCCTTGGTGGCTACGATTTAAAAACCATTGATAAAAAAGCCATTCGTCAATACATTAATTAC
CTACCACAACAGTCTTACGTCTTTTCAGGGACAATTTTAGAAAATTTAACCTTGGGAGCACCTGACAATATCACGCAAGA
AGAAATTCTGAAAGCTTGTGAAATCGCTGAAATCCGTGCTGATATTGAATTGATGCCACTAGCATACCATACCGAACTTT
CAGATGGTGCTGGGTTATCTGGTGGGCAAAAGCAACGTTTAGCTTTAGCACGCGCTTTACTGACACAAGCTCCCGTCTTG
ATTTTAGATGAAGCCACAAGTGGTCTTGATGTTCTAACGGAAAAACGTGTGATTAAAAATTTACTATCTCTCACAGACAA
AACTATTATTTTTGTTGCCCACCGTTTGAGCATTGCTGAACAATCTGACCGTGTCATTGTTCTAGATAAAGGACACGTTA
TCGAAGAAGGGCATCATAAACAACTCATCCAAAATCAAGGTTTCTATGCACAGTTATTTCATGAATAA

Domains

Predicted by InterProScan.

• Peptidase C39 family (Peptidase_C39) (3-140)

• ABC transporter (ABC_tran) (498-647)

• ABC transporter transmembrane region (ABC_membrane) (166-436)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	71.108	99.72	0.709
comA	Streptococcus mitis NCTC 12261	67.746	99.301	0.673
comA	Streptococcus pneumoniae Rx1	67.373	99.021	0.667
comA	Streptococcus pneumoniae D39	67.373	99.021	0.667
comA	Streptococcus pneumoniae R6	67.373	99.021	0.667
comA	Streptococcus mitis SK321	67.183	99.301	0.667
comA	Streptococcus pneumoniae TIGR4	67.09	99.021	0.664
comA	Streptococcus gordonii str. Challis substr. CH1	66.199	99.72	0.66