Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP/pknB   Type   Regulator
Locus tag   HRE60_RS06800 Genome accession   NZ_CP054153
Coordinates   1545902..1547776 (-) Length   624 a.a.
NCBI ID   WP_181670550.1    Uniprot ID   A0A7L6WKW1
Organism   Streptococcus salivarius strain DB-B5     
Function   activate comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1540902..1552776
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HRE60_RS06765 (HRE60_06765) rimM 1541278..1541796 (-) 519 WP_002884411.1 ribosome maturation factor RimM -
  HRE60_RS06780 (HRE60_06780) - 1542493..1543137 (-) 645 WP_002884791.1 response regulator transcription factor -
  HRE60_RS06785 (HRE60_06785) - 1543127..1544137 (-) 1011 WP_181670548.1 sensor histidine kinase -
  HRE60_RS06790 (HRE60_06790) liaF 1544134..1544832 (-) 699 WP_181670549.1 cell wall-active antibiotics response protein LiaF -
  HRE60_RS06795 (HRE60_06795) - 1544995..1545753 (-) 759 WP_002884314.1 potassium channel family protein -
  HRE60_RS06800 (HRE60_06800) stkP/pknB 1545902..1547776 (-) 1875 WP_181670550.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  HRE60_RS06805 (HRE60_06805) - 1547776..1548513 (-) 738 WP_181670551.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  HRE60_RS06810 (HRE60_06810) rsmB 1548557..1549879 (-) 1323 WP_181670552.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  HRE60_RS06815 (HRE60_06815) fmt 1549869..1550804 (-) 936 WP_181670553.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 624 a.a.        Molecular weight: 67883.53 Da        Isoelectric Point: 6.5786

>NTDB_id=451174 HRE60_RS06800 WP_181670550.1 1545902..1547776(-) (stkP/pknB) [Streptococcus salivarius strain DB-B5]
MIQVGKLFAGRYRILKSIGRGGMADVYLANDLILDNERVAIKVLRTNYQTDQVAVARFQREARAMAELSHPNIVAIRDIG
EEDGQQFLVMEYVDGSDLKKYIQDHAPLSNQDVVRIMGEVLSAMTLAHQKGIIHRDLKPQNVLLTKDGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKPLPSILAENRNVP
QALENVVIRATAKKLENRYNSTLEMSRDLVTSLHPSHRRDAKVVFDDMTDTKTLPKVDPVPSASLEKKAVAAEPSEPTPA
PSKQPRKKTTPAKKKKKKNFFSTLLKVFLGLVFIGIIIFAYLVFTNPDNVQVPNVVGQELSAAQTNIEGAGFKVGDVKEV
EDDSVDTGKVIKTDPTAGTTRKEGSSIDVYVSSGSKGFALKDYKGKNYKDAIEDLTSNYGVSEDQIDIQHVEDDNAEEGE
ILSQSPGKNKSFNPKDSKAKIKFRVATPKTVTMPDVTGLTVSTAVQTLNRKSISSSSIEYHDYNTGAKLDKDKVPSSTEV
LYQDPQAGTSVDGTVILYVSVATASSSLQSSSSSTTHSSSTSSSTDSTTSSTETSTEATHTELQ

Nucleotide


Download         Length: 1875 bp        

>NTDB_id=451174 HRE60_RS06800 WP_181670550.1 1545902..1547776(-) (stkP/pknB) [Streptococcus salivarius strain DB-B5]
ATGATCCAAGTTGGCAAATTGTTTGCTGGACGTTATCGAATCCTTAAGTCTATCGGGCGTGGTGGTATGGCGGATGTTTA
TCTGGCTAACGACCTGATTCTGGATAATGAAAGAGTAGCTATTAAGGTGCTACGTACCAATTACCAAACGGATCAGGTGG
CTGTGGCGCGTTTCCAGCGTGAAGCGCGTGCCATGGCAGAACTCAGTCATCCTAATATCGTTGCTATCCGAGATATTGGC
GAAGAAGACGGCCAGCAGTTTTTGGTGATGGAGTATGTGGATGGTTCGGACTTGAAGAAATATATTCAAGACCATGCGCC
ACTTTCTAACCAAGATGTTGTGCGTATCATGGGGGAGGTTCTTTCCGCCATGACTCTTGCCCACCAAAAGGGCATTATCC
ACCGTGACCTTAAGCCACAAAACGTTCTTTTAACTAAGGACGGTACAGCCAAGGTCACAGACTTCGGAATTGCGGTTGCC
TTTGCAGAGACTAGTCTAACTCAAACTAACTCTATGTTGGGTTCTGTCCACTACCTCTCACCAGAGCAGGCTCGTGGATC
GAAAGCAACTATCCAAAGCGACATCTATGCTATGGGTATTATGCTTTTTGAAATGTTGACAGGTCATATTCCTTATGATG
GTGACAGTGCAGTAACCATTGCACTCCAACATTTCCAAAAGCCACTCCCATCTATTTTGGCAGAGAACCGTAATGTTCCC
CAAGCCTTGGAAAACGTGGTTATTCGAGCAACAGCCAAAAAACTAGAGAATCGTTATAATAGTACTTTGGAAATGAGCCG
TGACTTGGTAACGAGTTTGCATCCTAGTCATCGACGCGATGCCAAGGTAGTCTTTGATGATATGACGGATACCAAGACCT
TGCCAAAGGTTGATCCAGTTCCATCTGCAAGTCTTGAGAAAAAAGCCGTTGCTGCTGAGCCATCAGAGCCTACACCTGCT
CCAAGTAAACAACCAAGGAAAAAAACGACACCAGCTAAGAAGAAAAAGAAGAAAAACTTTTTCTCAACCTTGCTCAAGGT
TTTCCTAGGACTTGTCTTTATTGGTATTATCATCTTTGCCTATTTGGTATTTACCAATCCTGATAATGTCCAGGTGCCTA
ATGTGGTCGGTCAAGAGTTGTCCGCAGCTCAGACTAACATTGAGGGTGCTGGATTTAAGGTAGGAGACGTTAAAGAAGTG
GAAGATGACTCTGTCGATACAGGCAAGGTCATCAAGACTGATCCTACAGCTGGAACTACACGAAAAGAAGGATCAAGCAT
TGATGTCTATGTTTCTTCTGGTAGTAAAGGTTTCGCTTTGAAAGACTACAAAGGTAAAAACTATAAGGATGCCATTGAGG
ACTTAACTTCGAATTATGGCGTTTCTGAGGATCAAATTGATATTCAGCATGTCGAAGACGATAATGCTGAAGAGGGAGAA
ATCCTATCTCAAAGTCCAGGGAAAAACAAGTCTTTCAATCCTAAGGATAGTAAGGCCAAGATTAAGTTCCGTGTGGCAAC
TCCTAAGACAGTTACCATGCCTGATGTGACTGGTTTGACGGTTTCAACAGCGGTTCAAACCTTGAATCGTAAGAGTATCT
CAAGTAGTAGTATCGAGTATCATGACTATAATACTGGTGCCAAGTTAGACAAGGATAAGGTTCCTAGCAGTACAGAGGTC
CTTTATCAAGATCCACAAGCTGGTACAAGTGTTGATGGTACAGTGATTCTCTATGTTTCAGTTGCAACAGCAAGTTCAAG
TCTACAGTCAAGCTCAAGCAGTACGACACATTCGTCATCGACGAGCTCGAGTACTGACAGTACAACTTCAAGCACTGAAA
CCTCGACAGAGGCTACTCACACAGAGCTACAGTAG

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-235)

PASTA domain (PASTA)

(441-505)

PASTA domain (PASTA)

(370-432)

PASTA domain (PASTA)

(511-580)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7L6WKW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP/pknB Streptococcus salivarius strain HSISS4

98.237

100

0.982
  pknB Streptococcus mutans UA159

67.159

86.859

0.583
  stkP Streptococcus pneumoniae TIGR4

52.151

93.109

0.486
  stkP Streptococcus pneumoniae D39

51.979

93.109

0.484
  stkP Streptococcus pneumoniae R6

51.979

93.109

0.484
  stkP Streptococcus pneumoniae Rx1

51.807

93.109

0.482