Detailed information NTG0445857

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: HA036_RS03365
• Genome accession: NZ_CP053639
• Coordinates: 626030..626917 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain 14732
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 621030..631917

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HA036_RS03335 (HA036_03345)	-	621049..621141 (+)	93	WP_010956583.1	hypothetical protein	-
HA036_RS03340 (HA036_03350)	-	621249..621746 (-)	498	WP_001065268.1	glutathione peroxidase	-
HA036_RS03345 (HA036_03355)	-	621756..622016 (-)	261	WP_001789910.1	hypothetical protein	-
HA036_RS03350 (HA036_03360)	-	622398..622511 (-)	114	WP_011447078.1	hypothetical protein	-
HA036_RS03355 (HA036_03365)	-	623170..625170 (-)	2001	WP_000776751.1	ABC transporter permease	-
HA036_RS03360 (HA036_03370)	-	625167..625922 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
HA036_RS03365 (HA036_03375)	braS	626030..626917 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
HA036_RS03370 (HA036_03380)	braR	626928..627593 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
HA036_RS03375 (HA036_03385)	-	627619..627819 (-)	201	WP_000604728.1	hypothetical protein	-
HA036_RS03380 (HA036_03390)	-	628017..629441 (+)	1425	WP_000953744.1	alkaline phosphatase	-
HA036_RS14805	-	629501..629602 (-)	102	WP_000731972.1	SE2200 family small protein	-
HA036_RS03390 (HA036_03400)	-	629724..630179 (-)	456	Protein_630	MarR family winged helix-turn-helix transcriptional regulator	-
HA036_RS03395 (HA036_03405)	-	630424..631185 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=445857 HA036_RS03365 WP_000143419.1 626030..626917(-) (braS) [Staphylococcus aureus strain 14732]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=445857 HA036_RS03365 WP_000143419.1 626030..626917(-) (braS) [Staphylococcus aureus strain 14732]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997