Detailed information NTG0443309

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: HLB24_RS13255
• Genome accession: NZ_CP053183
• Coordinates: 2688555..2689442 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143422.1
• Uniprot ID: A0AB73JC73
• Organism: Staphylococcus aureus strain Guangzhou-SAU071
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2683555..2694442

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HLB24_RS13225 (HLB24_13245)	-	2683564..2683656 (+)	93	WP_010956583.1	hypothetical protein	-
HLB24_RS13230 (HLB24_13250)	-	2683764..2684261 (-)	498	WP_001065268.1	glutathione peroxidase	-
HLB24_RS13235 (HLB24_13255)	-	2684271..2684531 (-)	261	WP_011382405.1	hypothetical protein	-
HLB24_RS13240 (HLB24_13260)	-	2684913..2685026 (-)	114	WP_078065157.1	hypothetical protein	-
HLB24_RS13245 (HLB24_13265)	-	2685695..2687695 (-)	2001	WP_057504557.1	ABC transporter permease	-
HLB24_RS13250 (HLB24_13270)	-	2687692..2688447 (-)	756	WP_000923775.1	ABC transporter ATP-binding protein	-
HLB24_RS13255 (HLB24_13275)	braS	2688555..2689442 (-)	888	WP_000143422.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
HLB24_RS13260 (HLB24_13280)	braR	2689453..2690118 (-)	666	WP_000697884.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
HLB24_RS13265 (HLB24_13285)	-	2690144..2690344 (-)	201	WP_000604725.1	hypothetical protein	-
HLB24_RS13270 (HLB24_13290)	-	2690542..2691966 (+)	1425	WP_000953738.1	alkaline phosphatase	-
HLB24_RS13990	-	2692026..2692127 (-)	102	WP_000731972.1	SE2200 family small protein	-
HLB24_RS13280 (HLB24_13300)	-	2692249..2692704 (-)	456	WP_000106183.1	MarR family winged helix-turn-helix transcriptional regulator	-
HLB24_RS13285 (HLB24_13305)	-	2692949..2693710 (-)	762	WP_000323448.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34031.29 Da
• Isoelectric Point: 5.8962

>NTDB_id=443309 HLB24_RS13255 WP_000143422.1 2688555..2689442(-) (braS) [Staphylococcus aureus strain Guangzhou-SAU071]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGVGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=443309 HLB24_RS13255 WP_000143422.1 2688555..2689442(-) (braS) [Staphylococcus aureus strain Guangzhou-SAU071]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTGTTGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	98.983	100	0.99