Detailed information NTG0443049

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: HLB22_RS09645
• Genome accession: NZ_CP053101
• Coordinates: 1974162..1975205 (-)
• Length: 347 a.a.
• NCBI ID: WP_029271699.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain EDCC5398
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1969162..1980205

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HLB22_RS09615 (HLB22_09615)	-	1969583..1970839 (-)	1257	WP_075583716.1	aminopeptidase	-
HLB22_RS09620 (HLB22_09620)	-	1970842..1971042 (-)	201	WP_000180460.1	DUF1128 family protein	-
HLB22_RS09625 (HLB22_09625)	-	1971189..1971653 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
HLB22_RS09630 (HLB22_09630)	-	1971660..1971935 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
HLB22_RS09635 (HLB22_09635)	-	1972213..1973430 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
HLB22_RS09640 (HLB22_09640)	vraR	1973543..1974172 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
HLB22_RS09645 (HLB22_09645)	vraS	1974162..1975205 (-)	1044	WP_029271699.1	sensor histidine kinase	Regulator
HLB22_RS09650 (HLB22_09650)	liaF	1975202..1975903 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
HLB22_RS09655 (HLB22_09655)	-	1975918..1976304 (-)	387	WP_001110179.1	hypothetical protein	-
HLB22_RS09660 (HLB22_09660)	map	1976521..1977279 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
HLB22_RS09665 (HLB22_09665)	-	1977808..1978794 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
HLB22_RS09670 (HLB22_09670)	-	1979225..1979638 (-)	414	WP_001670387.1	hypothetical protein	-
HLB22_RS09675 (HLB22_09675)	-	1979667..1979777 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40074.55 Da
• Isoelectric Point: 6.0577

>NTDB_id=443049 HLB22_RS09645 WP_029271699.1 1974162..1975205(-) (vraS) [Staphylococcus aureus strain EDCC5398]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERTLEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=443049 HLB22_RS09645 WP_029271699.1 1974162..1975205(-) (vraS) [Staphylococcus aureus strain EDCC5398]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAACTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	99.712	100	0.997