Detailed information NTG0430549

Bioinformatically predicted

Overview

• Name: stkP
• Type: Regulator
• Locus tag: HA248_RS08470
• Genome accession: NZ_CP050175
• Coordinates: 1653106..1655085 (-)
• Length: 659 a.a.
• NCBI ID: WP_000614540.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain PZ900701590
• Function: require for competence development; phosphorylate ComE (predicted from homology) Competence regulation

Genomic Context

Location: 1648106..1660085

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HA248_RS08440 (HA248_08420)	-	1648202..1649476 (-)	1275	WP_000704388.1	hydroxymethylglutaryl-CoA reductase, degradative	-
HA248_RS08445 (HA248_08425)	-	1649476..1650648 (-)	1173	WP_000151960.1	hydroxymethylglutaryl-CoA synthase	-
HA248_RS08450 (HA248_08430)	-	1650779..1651027 (-)	249	WP_001818278.1	hypothetical protein	-
HA248_RS08455 (HA248_08435)	-	1651095..1651720 (-)	626	Protein_1666	transposase	-
HA248_RS08460 (HA248_08440)	-	1651782..1652231 (-)	450	WP_000176924.1	threonine/serine exporter family protein	-
HA248_RS08465 (HA248_08445)	-	1652233..1652991 (-)	759	WP_000392877.1	threonine/serine exporter ThrE family protein	-
HA248_RS08470 (HA248_08450)	stkP	1653106..1655085 (-)	1980	WP_000614540.1	serine/threonine-protein kinase StkP	Regulator
HA248_RS08475 (HA248_08455)	-	1655082..1655822 (-)	741	WP_000406247.1	Stp1/IreP family PP2C-type Ser/Thr phosphatase	-
HA248_RS08480 (HA248_08460)	rsmB	1655837..1657150 (-)	1314	WP_001813311.1	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	-
HA248_RS08485 (HA248_08465)	fmt	1657143..1658078 (-)	936	WP_000163699.1	methionyl-tRNA formyltransferase	-

Sequence

Protein

• Length: 659 a.a.
• Molecular weight: 72316.86 Da
• Isoelectric Point: 9.0945

>NTDB_id=430549 HA248_RS08470 WP_000614540.1 1653106..1655085(-) (stkP) [Streptococcus pneumoniae strain PZ900701590]
MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEDGQQYLAMEYVAGLDLKRYIKEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSVIAENPSVP
QALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYNRRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIK
NPSQAVTEETYQPQAPKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANFEIGEEKTE
ASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSDVIAELKEKKVPDNLIKIEEEESNESEAGTV
LKQSLPEGTTYDLSKATQIVLTVAKKATTIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAG
TTYDVSKPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSVEGMVVEQSPRAGEKVDL
NKTRVKISIYKPKTTSATP

Nucleotide

• Length: 1980 bp

>NTDB_id=430549 HA248_RS08470 WP_000614540.1 1653106..1655085(-) (stkP) [Streptococcus pneumoniae strain PZ900701590]
ATGATCCAAATCGGCAAGATTTTTGCCGGACGCTATCGGATTGTCAAACAGATTGGTCGAGGAGGTATGGCGGATGTCTA
CCTAGCCAAAGACTTAATCTTAGATGGGGAAGAAGTGGCAGTGAAGGTTCTGAGGACTAACTACCAGACGGACCCGATAG
CTGTAGCTCGTTTTCAGCGTGAAGCGAGAGCTATGGCAGATCTAGACCATCCTCATATCGTTCGGATAACAGATATTGGT
GAGGAAGACGGTCAACAGTATCTTGCAATGGAGTATGTTGCTGGACTAGACCTCAAACGCTATATCAAGGAACATTATCC
TCTTTCTAATGAAGAAGCCGTCCGTATCATGGGACAAATTCTCTTGGCTATGCGCTTGGCCCATACTCGAGGAATTGTTC
ACAGGGACTTGAAACCTCAAAATATCCTTTTGACACCAGATGGGACGGCCAAGGTCACAGACTTTGGGATTGCTGTAGCC
TTTGCAGAGACAAGTCTGACCCAGACTAACTCGATGTTGGGCTCAGTTCATTACTTGTCACCAGAGCAGGCGCGTGGTTC
TAAGGCGACTGTGCAGAGTGATATCTATGCCATGGGGATTATTTTCTATGAGATGTTGACAGGCCATATCCCTTATGACG
GGGATAGCGCGGTGACCATTGCCCTCCAGCATTTCCAGAAACCCCTGCCGTCCGTTATTGCAGAAAATCCATCTGTACCT
CAGGCTTTAGAAAATGTTATTATCAAGGCAACTGCTAAAAAGTTGACCAATCGCTACCGCTCGGTTTCAGAGATGTATGT
GGACTTGTCTAGTAGCTTGTCCTACAATCGTAGAAATGAAAGTAAGTTAATCTTTGATGAAACGAGCAAGGCAGATACCA
AGACCTTGCCGAAGGTTTCTCAGAGTACCTTGACATCTATTCCTAAGGTTCAAGCGCAGACAGAACACAAATCAATCAAA
AACCCAAGCCAGGCTGTGACAGAGGAAACTTACCAACCACAAGCACCGAAAAAACATAGATTTAAGATGCGTTACCTGAT
TTTGTTGGCCAGCCTTGTATTGGTGGCAGCTTCTCTTATTTGGATACTATCCAGAACTCCTGCAACCATTGCCATTCCAG
ATGTGGCAGGTCAGACAGTTGCAGAGGCCAAGGCAACGCTCAAAAAAGCCAATTTTGAGATTGGTGAGGAGAAGACAGAG
GCTAGTGAAAAGGTGGAAGAAGGGCGGATTATCCGTACAGATCCTGGCGCTGGAACTGGTCGAAAAGAAGGAACGAAAAT
CAATCTGGTTGTCTCATCAGGCAAACAATCCTTCCAAATTAGTAATTATGTCGGCCGGAAATCTTCTGATGTTATCGCGG
AATTAAAAGAGAAAAAAGTTCCAGATAATTTGATTAAAATTGAGGAAGAAGAGTCGAATGAGAGTGAGGCTGGAACGGTC
CTGAAGCAAAGTCTACCAGAAGGTACGACCTATGACTTGAGCAAGGCAACTCAAATTGTTTTGACAGTAGCTAAAAAAGC
TACGACGATTCAATTAGGGAACTATATTGGACGGAACTCTACAGAAGTAATCTCAGAACTCAAGCAGAAGAAGGTTCCTG
AGAATTTGATTAAGATAGAGGAAGAAGAGTCCAGCGAAAGCGAACCAGGAACGATTATGAAACAAAGTCCAGGTGCCGGA
ACGACTTATGATGTGAGTAAACCTACTCAAATTGTCTTGACAGTAGCTAAAAAAGTTACAAGTGTTGCCATGCCGAGTTA
CATTGGTTCCAGCTTGGAGTTTACTAAGAACAATTTGATTCAAATTGTTGGGATTAAGGAAGCTAATATAGAAGTTGTAG
AAGTGACGACAGCGCCTGCAGGTAGTGTAGAAGGCATGGTTGTTGAACAAAGTCCTAGAGCAGGTGAAAAGGTAGACCTA
AATAAGACTAGAGTCAAGATTTCAATCTACAAACCTAAAACAACTTCAGCTACTCCTTAA

Domains

Predicted by InterproScan.

• Protein kinase domain (Pkinase) (12-227)

• PASTA domain (PASTA) (440-505)

• PASTA domain (PASTA) (582-651)

• PASTA domain (PASTA) (513-577)

• PASTA domain (PASTA) (371-432)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
stkP	Streptococcus pneumoniae TIGR4	99.848	100	0.998
stkP	Streptococcus pneumoniae D39	99.697	100	0.997
stkP	Streptococcus pneumoniae R6	99.697	100	0.997
stkP	Streptococcus pneumoniae Rx1	99.545	100	0.995
pknB	Streptococcus mutans UA159	52.65	88.771	0.467
stkP/pknB	Streptococcus salivarius strain HSISS4	51.807	88.164	0.457