Detailed information    

insolico Bioinformatically predicted

Overview

Name   irvR   Type   Regulator
Locus tag   IF725_RS13425 Genome accession   NZ_CP062412
Coordinates   2732527..2733240 (-) Length   237 a.a.
NCBI ID   WP_001031454.1    Uniprot ID   A0A0H2XG68
Organism   Staphylococcus aureus strain NAS_AN_181     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2727527..2738240
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IF725_RS13395 (IF725_13335) sph 2728091..2728921 (-) 831 Protein_2603 sphingomyelin phosphodiesterase -
  IF725_RS13400 (IF725_13340) - 2728972..2730009 (-) 1038 WP_240100856.1 site-specific integrase -
  IF725_RS13405 (IF725_13345) - 2730182..2730721 (-) 540 WP_000391618.1 type II toxin-antitoxin system PemK/MazF family toxin -
  IF725_RS13410 (IF725_13350) - 2730861..2731028 (-) 168 WP_031806878.1 hypothetical protein -
  IF725_RS13415 (IF725_13355) - 2731232..2731573 (-) 342 WP_000591749.1 hypothetical protein -
  IF725_RS13420 (IF725_13360) - 2731579..2732511 (-) 933 WP_000759682.1 exonuclease domain-containing protein -
  IF725_RS13425 (IF725_13365) irvR 2732527..2733240 (-) 714 WP_001031454.1 XRE family transcriptional regulator Regulator
  IF725_RS13430 (IF725_13370) - 2733203..2733376 (+) 174 WP_001801500.1 hypothetical protein -
  IF725_RS13435 (IF725_13375) - 2733373..2733636 (+) 264 WP_000854072.1 helix-turn-helix transcriptional regulator -
  IF725_RS13440 (IF725_13380) - 2733652..2733849 (+) 198 WP_001148862.1 hypothetical protein -
  IF725_RS13445 (IF725_13385) - 2733836..2734216 (-) 381 WP_000762521.1 DUF2513 domain-containing protein -
  IF725_RS13450 (IF725_13390) - 2734271..2734594 (+) 324 WP_001120201.1 DUF771 domain-containing protein -
  IF725_RS13455 (IF725_13395) - 2734591..2734752 (+) 162 WP_000048132.1 DUF1270 family protein -
  IF725_RS13460 (IF725_13400) - 2734847..2735149 (+) 303 WP_000165371.1 DUF2482 family protein -
  IF725_RS13465 (IF725_13405) - 2735154..2735414 (+) 261 WP_000291510.1 DUF1108 family protein -
  IF725_RS13470 (IF725_13410) - 2735423..2735686 (+) 264 WP_001205732.1 hypothetical protein -
  IF725_RS13475 (IF725_13415) - 2735695..2737638 (+) 1944 WP_000700555.1 AAA family ATPase -

Sequence

Protein


Download         Length: 237 a.a.        Molecular weight: 27017.58 Da        Isoelectric Point: 5.0545

>NTDB_id=430109 IF725_RS13425 WP_001031454.1 2732527..2733240(-) (irvR) [Staphylococcus aureus strain NAS_AN_181]
MNKERNIIIAKNIRKFLNDSNMSQKKLAELINIKPSTLSDYLNLRSNPSHGVIQRIADVFEVGKSDIDTTYKDDNDITSI
YNKLTPPRQENVLNYANEQLEEQNSKGDNVVDINSYKQEKTPVNVNGCVSAGVGERLHDETLFTEMVKGPIPTHDLALKV
NGDSMEPMFKDGEIIFVEKTHNIKNGQIGIFIIEEEAYVKKVFVEDDRLTLVSLNKDYDDLHFYRNESVRLIGKVIL

Nucleotide


Download         Length: 714 bp        

>NTDB_id=430109 IF725_RS13425 WP_001031454.1 2732527..2733240(-) (irvR) [Staphylococcus aureus strain NAS_AN_181]
ATGAACAAAGAAAGAAATATTATTATAGCCAAAAACATTAGAAAATTTCTCAACGATTCAAATATGTCTCAAAAGAAACT
TGCTGAACTCATTAACATAAAACCATCTACTTTAAGCGATTATTTAAATTTACGTTCCAACCCCTCTCACGGCGTTATAC
AAAGGATAGCTGATGTTTTCGAGGTTGGTAAAAGCGACATAGATACTACATACAAAGACGATAACGACATCACTTCCATA
TACAACAAACTCACACCTCCCCGCCAAGAAAACGTACTTAACTATGCAAATGAACAATTGGAAGAACAGAATTCTAAAGG
AGATAACGTTGTAGATATTAATTCATATAAACAGGAGAAAACTCCAGTTAACGTCAATGGTTGCGTCTCTGCTGGTGTAG
GAGAACGTTTACACGATGAAACGCTATTTACTGAAATGGTTAAAGGACCTATCCCCACACACGATTTAGCGTTAAAAGTA
AATGGTGATTCTATGGAACCTATGTTTAAAGATGGCGAAATCATATTTGTGGAGAAAACTCACAATATAAAGAATGGACA
AATTGGTATATTCATCATTGAAGAAGAAGCGTACGTTAAGAAAGTCTTTGTTGAAGATGATAGATTGACTCTAGTTTCAC
TAAATAAAGATTACGACGATCTACACTTTTATAGAAATGAAAGTGTGAGGTTAATTGGAAAAGTTATTTTATAA

Domains

Predicted by InterProScan.

Peptidase S24-like (Peptidase_S24)

(127-236)

Helix-turn-helix (HTH_3)

(13-63)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2XG68

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  irvR Streptococcus mutans UA159

33.929

100

0.401