Detailed information NTG0420465

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: M654_RS16290
• Genome accession: NZ_CP048273
• Coordinates: 3118525..3120855 (-)
• Length: 776 a.a.
• NCBI ID: WP_026587935.1
• Uniprot ID: A0A6I7FF56
• Organism: Bacillus sp. NSP9.1
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 3113525..3125855

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
M654_RS16265 (M654_016215)	gpr	3114271..3115377 (-)	1107	WP_026587930.1	GPR endopeptidase	-
M654_RS16270 (M654_016220)	rpsT	3115585..3115851 (+)	267	WP_026587931.1	30S ribosomal protein S20	-
M654_RS16275 (M654_016225)	-	3116012..3116305 (-)	294	WP_026587932.1	RNA polymerase alpha subunit C-terminal domain-containing protein	-
M654_RS23965	-	3116476..3116806 (-)	331	Protein_3260	winged helix-turn-helix transcriptional regulator	-
M654_RS16280 (M654_016230)	holA	3117025..3118047 (-)	1023	WP_026587933.1	DNA polymerase III subunit delta	-
M654_RS16285 (M654_016235)	-	3118282..3118413 (+)	132	WP_026587934.1	YqzM family protein	-
M654_RS16290 (M654_016240)	comEC	3118525..3120855 (-)	2331	WP_026587935.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
M654_RS16295 (M654_016245)	-	3120862..3121431 (-)	570	WP_026587936.1	ComE operon protein 2	-
M654_RS16300 (M654_016250)	comEA	3121500..3122129 (-)	630	WP_026587937.1	helix-hairpin-helix domain-containing protein	Machinery gene
M654_RS16305 (M654_016255)	comER	3122192..3123034 (+)	843	WP_256860380.1	late competence protein ComER	-
M654_RS16310 (M654_016260)	-	3123102..3123857 (-)	756	WP_026587939.1	class I SAM-dependent methyltransferase	-
M654_RS16315 (M654_016265)	rsfS	3123857..3124210 (-)	354	WP_026587940.1	ribosome silencing factor	-
M654_RS16320 (M654_016270)	yqeK	3124224..3124787 (-)	564	WP_026587941.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
M654_RS16325 (M654_016275)	-	3124777..3125346 (-)	570	WP_026587942.1	nicotinate-nucleotide adenylyltransferase	-
M654_RS16330 (M654_016280)	yhbY	3125367..3125657 (-)	291	WP_026587943.1	ribosome assembly RNA-binding protein YhbY	-

Sequence

Protein

• Length: 776 a.a.
• Molecular weight: 85472.14 Da
• Isoelectric Point: 9.1782

>NTDB_id=420465 M654_RS16290 WP_026587935.1 3118525..3120855(-) (comEC) [Bacillus sp. NSP9.1]
MDKHRLLPCGAISAAVGIAFAHSSSFLFFAVFISVPAAVSMVRKQYLLFLFCAVCCGFYSIYFLVIDHLNGSIYQEGAIQ
TSASVGNVPTIDGDRLSFKAETPDGESLKARYTIQSREEKRKLADLGPGSICFMKGELKKPKNATVPGTFNEKEYLRTQG
IYWNFAIQSIKNCKQKDALSSILLNIRKSGLDFIEDNMSETAAGVVCALIFGDRFLIEQEVLDGYQSLGIIHLLAISGLH
VGILAAALFYCLLRLGITREGAKWILIFALPAAAVITGGAPSVLRAVFMSDIYLLSSLSKKRLKSADVLSIAFLGLLLYN
PYLLFQAGFQLSFAVSFVFILSKGILLRPKNKTAQLLLASFLAQLGSLPILLFHFQEFSFLSVLANLFFVPFYLFAVIPL
SFASLLGLMLIRPAGEIAAGILDILLGWSHEAVKIISSADMFTFAASKPDGLQLLFYLGSIGMLLIAMENAVSLRKLFIP
SCLFISVFLWHVMLPHFTQDGEVTMLDIGQGDSIYISGPRQKGNVLIDTGGMVSFKKEPWRERKKAFSLAENVIIPFLAT
KGVQQLDALILTHADQDHVGEAEVLIKKHKVKELVVPIGYAADPADEKLLRTAIEHGVAVKAAKRGDKLNIGGLQFYVLS
PEKVDGDSKNNSSLVLWMKLGGLTWLLTGDLEQDGEREIMKAYPELKADVLKVGHHGSKGSTGENFIKQIKPKTALISAG
EHNRYGHPHKEVLDILKRHRVKVYRTDRDGAVQYLFDRGKGTFLLHPPYDKVHSTQ

Nucleotide

• Length: 2331 bp

>NTDB_id=420465 M654_RS16290 WP_026587935.1 3118525..3120855(-) (comEC) [Bacillus sp. NSP9.1]
ATGGACAAACACCGACTCCTCCCCTGCGGGGCAATTTCAGCGGCGGTTGGAATTGCCTTCGCCCACTCTTCATCATTCCT
CTTCTTCGCCGTGTTCATATCGGTGCCGGCCGCCGTCAGCATGGTCAGAAAACAGTACCTCCTTTTTCTATTTTGCGCAG
TGTGCTGCGGTTTTTACTCGATTTATTTTTTGGTGATTGACCATTTAAACGGCTCCATCTATCAAGAGGGTGCCATTCAA
ACGTCCGCATCAGTCGGAAATGTTCCAACAATCGACGGCGACCGCCTTTCTTTCAAAGCCGAAACCCCGGACGGAGAGTC
CTTGAAAGCCCGCTATACCATTCAGTCACGGGAAGAAAAAAGAAAGCTGGCCGACCTTGGCCCCGGCAGTATATGTTTCA
TGAAAGGCGAATTGAAAAAGCCTAAAAACGCGACGGTCCCCGGAACATTTAATGAAAAAGAATATTTGCGCACACAAGGC
ATCTACTGGAACTTTGCCATTCAATCTATCAAAAACTGCAAGCAGAAAGACGCGCTTTCTTCCATTTTGTTAAACATCAG
AAAATCAGGCCTGGATTTTATTGAAGATAACATGTCGGAAACCGCGGCCGGGGTTGTATGTGCGCTGATATTCGGCGATC
GGTTTCTCATTGAACAGGAAGTCCTTGACGGATATCAAAGCCTTGGAATCATCCACCTGCTAGCGATTTCGGGTCTCCAT
GTCGGCATTTTGGCCGCCGCGCTGTTTTATTGCCTGCTGCGCCTTGGCATTACGAGGGAAGGTGCAAAATGGATTTTGAT
TTTTGCACTTCCCGCTGCCGCCGTGATCACCGGCGGAGCTCCGTCCGTGTTGAGGGCCGTGTTTATGTCGGACATCTATC
TGCTTTCTTCATTGTCTAAAAAACGGCTGAAAAGCGCCGATGTTCTCAGCATAGCCTTCCTCGGCCTGTTGTTGTACAAC
CCGTATCTGCTCTTTCAGGCAGGTTTTCAGCTTTCCTTTGCAGTATCCTTCGTTTTTATTCTTTCAAAAGGCATATTGCT
CAGACCGAAAAACAAAACGGCGCAGCTGCTGCTTGCATCTTTTCTTGCTCAGCTCGGCTCGCTTCCGATCCTCCTTTTTC
ACTTTCAGGAGTTTTCCTTTCTCAGTGTTCTGGCGAATCTATTTTTCGTACCATTTTATTTATTTGCCGTGATCCCGCTG
TCGTTCGCCAGCTTGCTGGGGCTGATGTTGATTCGCCCCGCGGGGGAAATAGCGGCGGGAATCCTTGACATTTTACTTGG
ATGGAGCCACGAGGCTGTCAAAATCATATCTTCGGCAGATATGTTCACATTCGCTGCCAGCAAACCGGATGGGCTGCAGC
TGCTTTTTTATCTCGGGTCCATCGGTATGCTCCTTATTGCTATGGAAAATGCGGTCTCCCTCCGAAAACTTTTCATCCCT
TCCTGTCTTTTCATTTCCGTTTTTCTCTGGCATGTGATGCTGCCGCATTTCACACAAGATGGAGAGGTTACCATGCTTGA
TATCGGACAGGGTGACAGCATCTATATCAGTGGGCCCCGACAGAAAGGGAATGTTTTGATTGATACCGGGGGAATGGTTT
CGTTCAAAAAGGAGCCGTGGAGAGAAAGAAAAAAAGCTTTTTCCCTGGCGGAAAACGTGATTATCCCGTTTCTCGCTACC
AAAGGGGTTCAACAGCTTGATGCTTTGATTTTAACGCATGCCGACCAAGACCATGTCGGTGAAGCGGAAGTACTCATCAA
AAAACATAAGGTGAAAGAGCTGGTTGTTCCGATAGGCTATGCGGCCGATCCGGCGGATGAAAAGCTGCTTCGCACTGCTA
TCGAACATGGGGTTGCTGTAAAAGCTGCCAAAAGAGGCGATAAGCTGAACATAGGCGGTTTGCAATTTTATGTGCTTTCA
CCGGAAAAGGTGGATGGCGATAGCAAAAATAACAGCTCACTCGTTTTGTGGATGAAGCTGGGTGGTTTAACATGGCTTTT
AACAGGCGATTTGGAACAGGATGGCGAACGGGAGATCATGAAAGCCTATCCGGAACTGAAAGCCGATGTGTTGAAAGTCG
GCCATCACGGGAGTAAAGGGTCGACAGGAGAGAATTTCATCAAACAAATCAAGCCGAAGACAGCCCTGATTTCAGCCGGG
GAACATAATCGGTACGGCCATCCGCACAAGGAGGTGTTAGACATCTTAAAACGCCATCGCGTCAAGGTATACCGGACAGA
TCGCGACGGAGCAGTTCAATACCTATTTGACAGGGGAAAGGGAACGTTTTTGCTCCATCCCCCATATGATAAAGTACATT
CCACGCAATAA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (209-467)

• Metallo-beta-lactamase superfamily (Lactamase_B) (509-720)

• Domain of unknown function (DUF4131) (DUF4131) (27-171)

3D structure

• AlphaFold DB: A0A6I7FF56

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Bacillus subtilis subsp. subtilis str. 168	48.898	99.356	0.486