Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGD   Type   Machinery gene
Locus tag   H7792_RS00660 Genome accession   NZ_CP060643
Coordinates   103769..104197 (+) Length   142 a.a.
NCBI ID   WP_002986548.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain TSPY416     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 98769..109197
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7792_RS00640 (H7792_00650) - 101106..101471 (+) 366 WP_002986560.1 DUF1033 family protein -
  H7792_RS00645 (H7792_00655) comGA 101564..102502 (+) 939 WP_111684478.1 competence type IV pilus ATPase ComGA Machinery gene
  H7792_RS00650 (H7792_00660) comGB 102438..103466 (+) 1029 WP_228650395.1 competence type IV pilus assembly protein ComGB Machinery gene
  H7792_RS00655 (H7792_00665) comGC 103468..103794 (+) 327 WP_002986552.1 competence type IV pilus major pilin ComGC Machinery gene
  H7792_RS00660 (H7792_00670) comGD 103769..104197 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD Machinery gene
  H7792_RS00665 (H7792_00675) comGE 104154..104438 (+) 285 WP_011284422.1 competence type IV pilus minor pilin ComGE Machinery gene
  H7792_RS00670 (H7792_00680) comGF 104431..104865 (+) 435 WP_002992738.1 competence type IV pilus minor pilin ComGF Machinery gene
  H7792_RS00675 (H7792_00685) comGG 104849..105175 (+) 327 WP_010921801.1 competence type IV pilus minor pilin ComGG -
  H7792_RS00680 (H7792_00690) comGH 105273..106226 (+) 954 WP_002987790.1 class I SAM-dependent methyltransferase Machinery gene
  H7792_RS00685 (H7792_00695) - 106285..107481 (+) 1197 WP_010921803.1 acetate kinase -
  H7792_RS00690 (H7792_00700) - 107668..107976 (+) 309 Protein_90 hypothetical protein -
  H7792_RS00695 (H7792_00705) proC 108059..108829 (-) 771 WP_038433852.1 pyrroline-5-carboxylate reductase -

Sequence

Protein


Download         Length: 142 a.a.        Molecular weight: 16310.04 Da        Isoelectric Point: 10.3481

>NTDB_id=415942 H7792_RS00660 WP_002986548.1 103769..104197(+) (comGD) [Streptococcus pyogenes strain TSPY416]
MKKPVLAIKAFTLLETLLSLSVMSFIILGLSVPVTKSYQKVEEHLFFSHFEHLYRHQQKLAILQQKQRVLDISSTKIVTE
GNSLTVPKSITVNHPYRLVIDQMGGNHSLAKIIFDMTDRRFKYQFYLGSGNYQKTSQSLHSP

Nucleotide


Download         Length: 429 bp        

>NTDB_id=415942 H7792_RS00660 WP_002986548.1 103769..104197(+) (comGD) [Streptococcus pyogenes strain TSPY416]
ATGAAAAAGCCCGTCTTAGCAATTAAAGCTTTTACTTTGCTTGAAACTTTACTAAGTTTGTCAGTGATGAGTTTCATTAT
ATTGGGATTGTCTGTACCAGTGACAAAAAGCTATCAAAAAGTAGAAGAGCATCTGTTTTTTAGCCATTTTGAACATTTGT
ATCGACATCAGCAAAAGTTAGCCATATTACAGCAAAAACAGCGCGTCTTGGATATTTCTTCAACAAAAATTGTTACAGAA
GGTAATAGCCTAACAGTTCCTAAATCAATAACAGTGAATCATCCTTATCGGTTAGTTATTGATCAGATGGGAGGCAACCA
TTCCTTAGCCAAAATTATTTTTGACATGACTGATCGACGCTTTAAATACCAATTTTATCTAGGGAGTGGGAATTATCAAA
AAACAAGTCAAAGCTTACATAGCCCTTGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGD Streptococcus mutans UA159

45.736

90.845

0.415
  comGD Streptococcus mutans UA140

45.736

90.845

0.415
  comGD/cglD Streptococcus mitis NCTC 12261

40.441

95.775

0.387
  comGD Streptococcus gordonii str. Challis substr. CH1

40.458

92.254

0.373
  comGD/cglD Streptococcus mitis SK321

39.695

92.254

0.366
  comGD/cglD Streptococcus pneumoniae Rx1

39.695

92.254

0.366
  comGD/cglD Streptococcus pneumoniae D39

39.695

92.254

0.366
  comGD/cglD Streptococcus pneumoniae R6

39.695

92.254

0.366

Multiple sequence alignment