Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGD   Type   Machinery gene
Locus tag   H7797_RS00665 Genome accession   NZ_CP060639
Coordinates   104266..104694 (+) Length   142 a.a.
NCBI ID   WP_109991901.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain TSPY153     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 99266..109694
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7797_RS00645 (H7797_00650) - 101582..101947 (+) 366 WP_002986560.1 DUF1033 family protein -
  H7797_RS00650 (H7797_00655) comGA 102040..102993 (+) 954 WP_030126921.1 competence type IV pilus ATPase ComGA Machinery gene
  H7797_RS00655 (H7797_00660) comGB 102929..103963 (+) 1035 WP_011054115.1 competence type IV pilus assembly protein ComGB Machinery gene
  H7797_RS00660 (H7797_00665) comGC 103965..104291 (+) 327 WP_228637011.1 competence type IV pilus major pilin ComGC Machinery gene
  H7797_RS00665 (H7797_00670) comGD 104266..104694 (+) 429 WP_109991901.1 competence type IV pilus minor pilin ComGD Machinery gene
  H7797_RS00670 (H7797_00675) comGE 104651..104935 (+) 285 WP_269460045.1 competence type IV pilus minor pilin ComGE Machinery gene
  H7797_RS00675 (H7797_00680) comGF 104928..105362 (+) 435 WP_002987783.1 competence type IV pilus minor pilin ComGF Machinery gene
  H7797_RS00680 (H7797_00685) comGG 105346..105672 (+) 327 WP_009880358.1 competence type IV pilus minor pilin ComGG -
  H7797_RS00685 (H7797_00690) comGH 105770..106723 (+) 954 WP_002987790.1 class I SAM-dependent methyltransferase Machinery gene
  H7797_RS00690 (H7797_00695) - 106782..107978 (+) 1197 WP_002987791.1 acetate kinase -
  H7797_RS00695 (H7797_00700) - 108165..108473 (+) 309 WP_010921804.1 hypothetical protein -
  H7797_RS00700 (H7797_00705) proC 108556..109326 (-) 771 WP_111692971.1 pyrroline-5-carboxylate reductase -

Sequence

Protein


Download         Length: 142 a.a.        Molecular weight: 16329.09 Da        Isoelectric Point: 10.4607

>NTDB_id=415562 H7797_RS00665 WP_109991901.1 104266..104694(+) (comGD) [Streptococcus pyogenes strain TSPY153]
MKKPVLAIKAFTLLETLLSLSVMSFIILGLSVPVTKSYQKVEEHLFFSRFEHLYRHQQKLAILQQKQRVLDISSTKIVTE
GNSLTVPKSITVNHPYRLVIDQMGGNHSLAKIIFDMTDRRFKYQFYLGSGNYQKTSQSLHSP

Nucleotide


Download         Length: 429 bp        

>NTDB_id=415562 H7797_RS00665 WP_109991901.1 104266..104694(+) (comGD) [Streptococcus pyogenes strain TSPY153]
ATGAAAAAGCCCGTCTTAGCAATTAAAGCTTTTACTTTGCTTGAAACTTTACTAAGTTTGTCAGTGATGAGTTTCATTAT
ATTGGGATTGTCTGTACCAGTGACAAAAAGCTATCAAAAAGTAGAAGAGCATCTGTTTTTTAGCCGTTTTGAACATTTGT
ATCGACATCAGCAAAAGTTAGCCATATTACAGCAAAAACAGCGCGTCTTGGATATTTCTTCAACAAAAATTGTTACAGAA
GGTAATAGCCTAACAGTTCCTAAATCAATAACAGTGAATCATCCTTATCGGTTAGTTATTGATCAGATGGGAGGCAACCA
TTCCTTAGCTAAAATTATTTTTGACATGACTGATCGACGCTTTAAATACCAATTTTATCTAGGGAGTGGGAATTATCAAA
AAACAAGTCAAAGCTTACATAGCCCTTGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGD Streptococcus mutans UA159

45.736

90.845

0.415
  comGD Streptococcus mutans UA140

45.736

90.845

0.415
  comGD/cglD Streptococcus mitis NCTC 12261

40.441

95.775

0.387
  comGD Streptococcus gordonii str. Challis substr. CH1

40.458

92.254

0.373
  comGD/cglD Streptococcus mitis SK321

39.695

92.254

0.366
  comGD/cglD Streptococcus pneumoniae Rx1

39.695

92.254

0.366
  comGD/cglD Streptococcus pneumoniae D39

39.695

92.254

0.366
  comGD/cglD Streptococcus pneumoniae R6

39.695

92.254

0.366