Detailed information NTG0409102

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: GP482_RS01610
• Genome accession: NZ_CP046875
• Coordinates: 311866..314100 (+)
• Length: 744 a.a.
• NCBI ID: WP_174235048.1
• Uniprot ID: -
• Organism: Streptococcus ruminicola strain CNU_77-61
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 306866..319100

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GP482_RS01585 (GP482_01585)	-	307561..309135 (+)	1575	WP_158913341.1	DEAD/DEAH box helicase	-
GP482_RS01590 (GP482_01590)	-	309213..309500 (-)	288	WP_158913343.1	GIY-YIG nuclease family protein	-
GP482_RS01595 (GP482_01595)	-	309475..310236 (-)	762	WP_158913346.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
GP482_RS01600 (GP482_01600)	-	310353..311099 (+)	747	WP_158913348.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
GP482_RS01605 (GP482_01605)	-	311196..311876 (+)	681	WP_158913350.1	helix-hairpin-helix domain-containing protein	-
GP482_RS01610 (GP482_01610)	comEC/celB	311866..314100 (+)	2235	WP_174235048.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
GP482_RS01615 (GP482_01615)	-	314206..314784 (+)	579	WP_039697246.1	HD domain-containing protein	-
GP482_RS01620 (GP482_01620)	-	314796..315518 (+)	723	WP_235631761.1	hypothetical protein	-
GP482_RS01625 (GP482_01625)	holA	315570..316607 (+)	1038	WP_174235032.1	DNA polymerase III subunit delta	-
GP482_RS01630 (GP482_01630)	sodA	316702..317313 (+)	612	WP_158913356.1	superoxide dismutase SodA	-
GP482_RS01635 (GP482_01635)	-	317415..318140 (+)	726	WP_039697215.1	YebC/PmpR family DNA-binding transcriptional regulator	-

Sequence

Protein

• Length: 744 a.a.
• Molecular weight: 84239.71 Da
• Isoelectric Point: 9.2036

>NTDB_id=409102 GP482_RS01610 WP_174235048.1 311866..314100(+) (comEC/celB) [Streptococcus ruminicola strain CNU_77-61]
MLTKYFPIKPIQLAFLLILLYYFCFSKVIGCLMFLLLALLFLWQQYGWKAWCQVSLCLAFFAIFFLTKANQTEQAYQAAP
AHLTKIQMIPDTISVNGDLLSFRGKEAGQTYQVFYTLKSEKEQKFFKNLNQTMLLSGQVDLEEATPKRNFGGFDYRTYLK
HEGIYRIANLSSITEMRQQSSLSFFERLHELRRQAIVSIQRNFPAPMQHYMTGLLFGYLDKSFDEMSDVYTSLGIIHLFA
LSGMQVGFFVGVFRYFFLRLGLRRDYVDILQIPFSLVYAGLTGFSVSVVRSLIQSAFANLGIKKLDNLAFTLMTLFILMP
NFLLTTGGILSFTYAFILSFIDFDELSHYRKILTECLAISLGSLPVLLYFFSVFQPLSLLLTAIFSLAFDTLILPVLTFV
FLLSPLVKITALNPFFVFLETIIKFSKSLIGTPLVFGRPSLGILLLLLLTIGLLYDCYRHKKVAIFLFSIIALLFFQIKH
PLENEVTVVDIGQGDSILVRDVKGQTLLIDVGGKVSFSEKKSWQKRLADSNAERTLIPYLKSRGIGKIDQLVLTHTDTDH
MGDMLEVAKELKIGQVLVSPGSLTKPDFVVKLRQMKTPVRAVSAGDNLPIMGSHLQVLYPNTVGDGGNNDSVVLYGNLLG
KNFLFTGDLEEEGEEQMMATYPNLPVDVLKAGHHGSKGSSSPEFLNHISPQMALISAGQNNRYKHPHQETLERFQAQNMT
IYRTDQQGAIRFRGLNHWKIETVR

Nucleotide

• Length: 2235 bp

>NTDB_id=409102 GP482_RS01610 WP_174235048.1 311866..314100(+) (comEC/celB) [Streptococcus ruminicola strain CNU_77-61]
CTGTTGACTAAGTATTTTCCTATTAAGCCAATTCAATTGGCTTTTTTGCTCATTTTGCTCTATTATTTTTGCTTTTCAAA
AGTGATTGGGTGTTTGATGTTTCTTTTGCTAGCCTTGCTGTTTTTATGGCAACAGTATGGTTGGAAGGCTTGGTGTCAGG
TTTCACTGTGCTTGGCTTTCTTTGCGATATTTTTCCTGACTAAGGCTAATCAGACAGAACAGGCTTATCAAGCGGCGCCA
GCTCATTTAACAAAAATTCAGATGATTCCTGATACGATTTCGGTTAATGGTGATTTATTATCCTTTCGAGGTAAGGAAGC
TGGGCAGACTTACCAAGTTTTTTATACCTTGAAGTCAGAAAAAGAGCAGAAATTTTTTAAAAATCTTAATCAAACAATGC
TTTTATCAGGGCAGGTGGACTTAGAAGAAGCAACGCCCAAACGTAATTTTGGTGGTTTTGATTACCGCACTTACCTTAAA
CATGAAGGTATTTATCGGATTGCTAATCTTTCTTCGATTACTGAAATGAGACAGCAGAGCTCTTTAAGTTTTTTTGAACG
ACTACATGAACTTAGAAGACAGGCGATTGTCAGTATTCAAAGGAATTTTCCTGCCCCAATGCAACATTATATGACTGGCC
TTTTGTTTGGATATTTGGATAAGTCTTTTGATGAGATGAGTGATGTATACACGAGTTTAGGGATTATTCATCTTTTTGCT
CTGTCTGGTATGCAGGTTGGCTTTTTTGTCGGTGTTTTTCGCTATTTCTTTTTGCGACTTGGCTTAAGGCGTGATTATGT
GGACATACTGCAAATCCCGTTTTCACTTGTATATGCTGGCTTGACAGGCTTTTCGGTTTCAGTTGTTCGGAGCCTTATTC
AGTCTGCTTTTGCAAATCTTGGCATAAAAAAATTAGATAATCTTGCCTTTACTTTAATGACCCTTTTTATTTTGATGCCA
AATTTCCTGCTGACAACAGGAGGAATTCTTTCTTTTACCTACGCTTTTATCCTGAGTTTTATTGATTTTGATGAGCTTAG
TCATTATCGAAAAATCCTTACAGAATGTTTGGCGATTTCGCTGGGAAGTTTACCGGTTTTGCTATATTTCTTCTCAGTAT
TTCAACCTTTGTCGCTGCTTTTAACAGCTATTTTTTCACTGGCTTTTGATACGCTTATCTTACCTGTTTTGACCTTTGTT
TTTCTTTTATCACCTCTGGTTAAAATTACCGCGTTAAATCCATTTTTTGTTTTTTTGGAAACTATCATCAAATTTAGCAA
GTCGCTGATTGGTACCCCACTCGTTTTTGGCAGACCAAGTTTAGGAATTTTGTTGCTATTACTTTTAACAATAGGACTTC
TCTATGACTGTTATCGACACAAAAAAGTGGCCATTTTCCTTTTTAGCATAATAGCTCTGCTATTTTTCCAAATCAAGCAT
CCGCTAGAAAACGAAGTGACGGTGGTTGACATTGGGCAGGGAGATAGCATTTTGGTGCGAGATGTAAAAGGGCAGACGCT
GTTAATTGACGTCGGAGGAAAAGTGAGTTTTAGTGAGAAAAAATCGTGGCAAAAGCGCTTAGCTGATAGCAATGCTGAGC
GGACACTGATTCCTTATTTGAAAAGTCGAGGAATTGGTAAAATTGACCAGTTGGTTTTGACGCACACGGATACCGACCAT
ATGGGTGATATGCTGGAAGTCGCAAAAGAGCTGAAAATTGGTCAAGTCCTGGTGAGTCCAGGAAGTCTCACAAAGCCAGA
TTTTGTGGTTAAACTTCGACAAATGAAGACGCCGGTTCGCGCAGTTTCTGCAGGAGATAACTTGCCAATTATGGGAAGTC
ACTTGCAGGTGCTCTATCCAAATACTGTTGGTGATGGTGGAAATAATGATTCTGTGGTGCTTTATGGCAACCTTCTTGGT
AAGAATTTCTTATTTACTGGAGACTTGGAAGAAGAGGGCGAAGAGCAGATGATGGCAACTTACCCCAATCTGCCAGTCGA
TGTCTTAAAAGCAGGACATCACGGTTCAAAAGGGTCGTCGAGCCCAGAATTTCTAAATCACATTTCACCACAAATGGCTT
TGATTTCCGCAGGGCAAAATAACCGCTACAAACACCCTCACCAAGAAACGCTTGAACGATTTCAAGCACAAAACATGACC
ATTTACCGCACAGACCAACAGGGCGCTATCCGCTTTAGAGGATTAAACCACTGGAAAATTGAAACGGTGAGATGA

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (28-174)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-684)

• Competence protein (Competence) (214-455)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	50.875	99.866	0.508
comEC/celB	Streptococcus mitis NCTC 12261	50.742	99.597	0.505
comEC/celB	Streptococcus pneumoniae TIGR4	49.865	99.731	0.497
comEC/celB	Streptococcus pneumoniae Rx1	49.326	99.731	0.492
comEC/celB	Streptococcus pneumoniae D39	49.326	99.731	0.492
comEC/celB	Streptococcus pneumoniae R6	49.326	99.731	0.492
comEC	Lactococcus lactis subsp. cremoris KW2	47.581	100	0.476