Detailed information NTG0404877

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: GE024_RS10055
• Genome accession: NZ_CP046521
• Coordinates: 2036158..2038602 (-)
• Length: 814 a.a.
• NCBI ID: WP_093999118.1
• Uniprot ID: -
• Organism: Streptococcus canis strain HL_100
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 2031158..2043602

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GE024_RS10025 (GE024_10075)	-	2031162..2031632 (+)	471	WP_093999121.1	8-oxo-dGTP diphosphatase	-
GE024_RS11265	-	2031975..2032598 (-)	624	WP_254428430.1	hypothetical protein	-
GE024_RS11270	-	2032616..2033191 (-)	576	WP_232038592.1	hypothetical protein	-
GE024_RS10035 (GE024_10085)	-	2033197..2033712 (-)	516	WP_138114335.1	lanthionine synthetase LanC family protein	-
GE024_RS11015 (GE024_10090)	-	2033693..2033773 (-)	81	Protein_1929	XRE family transcriptional regulator	-
GE024_RS10045 (GE024_10095)	groL	2034029..2035654 (-)	1626	WP_003045626.1	chaperonin GroEL	-
GE024_RS10050 (GE024_10100)	groES	2035690..2035980 (-)	291	WP_093999119.1	co-chaperone GroES	-
GE024_RS10055 (GE024_10105)	clpC	2036158..2038602 (-)	2445	WP_093999118.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
GE024_RS10060 (GE024_10110)	-	2038602..2039063 (-)	462	WP_093999117.1	CtsR family transcriptional regulator	-
GE024_RS10065 (GE024_10115)	-	2039262..2039465 (-)	204	WP_003045634.1	cold-shock protein	-
GE024_RS10070 (GE024_10120)	-	2039804..2040760 (+)	957	WP_093999116.1	amidohydrolase family protein	-
GE024_RS10075 (GE024_10125)	-	2040896..2041324 (+)	429	WP_003045638.1	MarR family winged helix-turn-helix transcriptional regulator	-
GE024_RS10080 (GE024_10130)	-	2041338..2042729 (+)	1392	WP_138114337.1	GNAT family N-acetyltransferase	-
GE024_RS10085 (GE024_10135)	-	2042827..2043105 (+)	279	WP_093999114.1	GNAT family N-acetyltransferase	-

Sequence

Protein

• Length: 814 a.a.
• Molecular weight: 90379.06 Da
• Isoelectric Point: 6.7392

>NTDB_id=404877 GE024_RS10055 WP_093999118.1 2036158..2038602(-) (clpC) [Streptococcus canis strain HL_100]
MIMYSLKMQEIFRQAQFQAARFDSHYLETWHILLAMARVDQSLAGLVLSEFDAKVAVEEYEAAAILAIGKSPKDQVSHVD
FKPQSKTLTNVLQFAQAISQITKDPEVGSEHVLFAMLLNPDIMASRLLEMAGYRIKDKGNGEPRLADLRKAIEIHAGYSK
ETIKTIHELRKPKKTKVQGTFSDMMKPPSTTGDLADFTRDLTEMAKQGLLEPVIGRDAEVSRMIQVLSRKTKNNPVLVGD
AGVGKTALAYGLAQRIVNGAIPYELQDMRVLELDMMSVVAGTRFRGDFEERMNQIIDDIEADGKIILFVDELHTIMGSGS
GIDSTLDAANILKPALSRGTLHMVGATTQEEYQKHIEKDAALSRRFAKILIEEPNLEDAYQILLGLKTSYETYHNVSISD
QAVHTAVKMAHRYLTSKNLPDSAIDLLDEASATVQSMVKKSSSEIITPIDQALLDGDIKKVSRLLAKEAKGQTRRPRPVT
EDDIMATLSKLSGIPLEKLSQADSKKYLNLEKELHKRVIGQEDAVSAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVGKT
ELAKALAEVLFDDASALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNMLLQ
VLDDGMLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGVKGISHDHQAMEKRILEELKKAYRPEFINRIDEKVVFH
SLTQENMREVVKIMVQPLIASLAEKGITLKFQPMALKYLSEEGYDVEMGARPLRRTLQTQVEDKLSELILAGDLASGHTL
KIGLSHGKLSFNVG

Nucleotide

• Length: 2445 bp

>NTDB_id=404877 GE024_RS10055 WP_093999118.1 2036158..2038602(-) (clpC) [Streptococcus canis strain HL_100]
ATGATCATGTATTCATTGAAGATGCAAGAAATCTTTAGGCAGGCACAGTTTCAAGCAGCCCGCTTTGACAGCCACTACCT
AGAAACTTGGCATATCTTGTTAGCCATGGCTAGAGTTGACCAGTCCTTAGCAGGTCTAGTGCTAAGTGAATTTGATGCTA
AAGTTGCAGTGGAAGAATACGAAGCTGCCGCTATTTTAGCTATAGGAAAAAGTCCTAAAGATCAGGTGTCACACGTGGAT
TTTAAGCCTCAATCCAAGACCTTGACGAATGTGTTACAGTTTGCGCAGGCTATTAGTCAAATCACTAAAGACCCAGAAGT
CGGCTCTGAACATGTGCTCTTTGCCATGCTACTCAATCCTGATATTATGGCAAGTCGTCTCTTGGAAATGGCTGGGTATC
GCATCAAAGATAAAGGAAATGGGGAACCTCGCTTAGCTGATTTGCGAAAGGCCATTGAGATTCACGCAGGTTATAGCAAA
GAAACCATTAAGACTATCCATGAGTTACGCAAACCAAAGAAAACGAAGGTTCAAGGAACCTTCTCAGATATGATGAAACC
ACCAAGCACGACGGGTGATTTGGCTGACTTCACCAGAGATTTGACCGAGATGGCAAAACAGGGTCTGCTAGAGCCTGTCA
TTGGTCGTGATGCCGAAGTATCTCGCATGATTCAAGTGCTCAGTCGTAAAACCAAAAATAATCCTGTTCTTGTTGGAGAT
GCAGGGGTTGGTAAAACTGCCCTTGCCTATGGTCTTGCCCAACGTATTGTGAATGGAGCCATTCCTTATGAACTGCAAGA
CATGCGCGTCCTCGAATTGGACATGATGAGCGTCGTTGCGGGGACACGTTTTCGTGGTGATTTTGAAGAACGCATGAACC
AGATTATTGATGACATTGAAGCAGATGGCAAGATTATCCTCTTTGTGGATGAATTGCATACCATTATGGGGTCAGGAAGC
GGTATTGATAGCACACTTGATGCTGCTAATATTTTGAAACCAGCCCTATCTCGTGGCACCCTTCACATGGTCGGAGCAAC
AACGCAGGAAGAGTACCAAAAACATATTGAAAAGGACGCCGCTCTTTCTCGCCGCTTTGCCAAAATTTTAATTGAAGAGC
CTAACCTAGAAGACGCCTATCAGATTTTACTAGGTTTGAAGACTTCCTATGAAACCTACCATAATGTGTCAATTTCTGAT
CAGGCAGTGCATACAGCTGTTAAAATGGCGCATCGCTACCTAACTAGTAAAAATCTTCCAGATTCAGCCATCGATTTGTT
GGACGAAGCTAGCGCTACAGTCCAAAGCATGGTTAAAAAATCAAGTTCGGAAATCATCACACCAATAGATCAGGCACTTC
TTGACGGTGATATAAAAAAGGTTTCACGTCTTTTGGCCAAAGAAGCTAAGGGGCAGACGAGAAGGCCAAGGCCAGTAACA
GAAGACGATATTATGGCAACCCTGAGCAAATTATCAGGGATTCCATTGGAAAAACTCAGTCAGGCTGATAGCAAAAAATA
CCTCAATCTTGAAAAAGAATTGCACAAGCGCGTGATTGGACAAGAAGACGCTGTTTCAGCCATTTCTAGAGCAATCCGTC
GTAATCAATCGGGTATTCGCACTGGTAAACGTCCAATTGGTTCTTTCATGTTCCTTGGACCTACTGGTGTTGGGAAGACT
GAATTGGCTAAAGCTTTGGCAGAAGTCCTCTTTGATGACGCGTCAGCCCTTATCCGCTTTGACATGTCAGAGTATATGGA
AAAATTTGCGGCATCTCGCCTTAATGGAGCGCCTCCAGGCTATGTCGGTTACGATGAGGGCGGTGAATTAACAGAGAAGG
TCAGAAACAAGCCTTATTCTGTCCTTCTCTTTGACGAGGTGGAAAAAGCCCACCCTGACATTTTCAACATGCTCTTACAA
GTGCTTGATGACGGTATGTTGACAGATAGCCGTGGGCGTAAGGTGGACTTCTCAAATACCATTATTATCATGACTAGTAA
TCTAGGGGCAACAGCTCTGCGGGATGATAAAACAGTTGGCTTTGGGGTAAAAGGTATCAGCCATGACCACCAAGCCATGG
AAAAACGGATTTTGGAAGAGTTGAAAAAAGCTTATCGACCAGAATTTATCAACCGAATTGATGAAAAGGTTGTCTTCCAT
AGCCTTACCCAAGAGAATATGAGGGAAGTGGTCAAGATTATGGTGCAGCCATTGATTGCTAGTTTAGCAGAAAAAGGCAT
TACCCTCAAATTCCAGCCAATGGCTCTCAAGTACCTTTCAGAGGAAGGCTATGATGTGGAAATGGGTGCTCGTCCATTGC
GCCGTACTTTGCAAACGCAGGTAGAAGACAAACTATCCGAATTGATTCTTGCTGGTGACTTGGCAAGTGGTCACACCCTG
AAAATTGGGCTTTCCCATGGCAAACTCAGCTTTAACGTTGGGTAA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (544-715)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (722-801)

• AAA lid domain (AAA_lid_9) (376-453)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (95-132)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (15-53)

• ATPase family associated with various cellular activities (AAA) (AAA) (236-368)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus mutans UA159	76.015	99.877	0.759
clpC	Streptococcus thermophilus LMD-9	72.426	100	0.726
clpC	Streptococcus thermophilus LMG 18311	72.304	100	0.725
clpC	Streptococcus pneumoniae TIGR4	65.602	100	0.656
clpC	Streptococcus pneumoniae Rx1	65.602	100	0.656
clpC	Streptococcus pneumoniae D39	65.602	100	0.656
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	48.568	100	0.5
clpC	Bacillus subtilis subsp. subtilis str. 168	43.63	100	0.446