Detailed information NTG0040078

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: SGGBAA2069_RS11725
• Genome accession: NC_015215
• Coordinates: 2354130..2355395 (+)
• Length: 421 a.a.
• NCBI ID: WP_013643604.1
• Uniprot ID: -
• Organism: Streptococcus gallolyticus subsp. gallolyticus ATCC BAA-2069
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2349130..2360395

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SGGBAA2069_RS11700 (SGGBAA2069_c23050)	-	2350094..2352688 (+)	2595	WP_013643602.1	YfhO family protein	-
SGGBAA2069_RS11720 (SGGBAA2069_c23070)	rlmH	2353441..2353920 (-)	480	WP_009855220.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
SGGBAA2069_RS11725 (SGGBAA2069_c23080)	htrA	2354130..2355395 (+)	1266	WP_013643604.1	S1C family serine protease	Regulator
SGGBAA2069_RS11730 (SGGBAA2069_c23090)	spo0J	2355465..2356241 (+)	777	WP_009855222.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 421 a.a.
• Molecular weight: 43832.63 Da
• Isoelectric Point: 4.0940

>NTDB_id=40078 SGGBAA2069_RS11725 WP_013643604.1 2354130..2355395(+) (htrA) [Streptococcus gallolyticus subsp. gallolyticus ATCC BAA-2069]
MKKIKLPKLPKLPKFNYKNWLKPLGVILVGFIAGIAGTILVLNMAGISITNVSGSSTKTTTSSVSYSNSNDTTKAVEKVQ
DAVVSVINYKSDSSSSTSDLYNQMFGNDSDSSSDSSSTDDLTVYSEGSGVIYKKDGDSAYVVTNNHVIDGAEQIEIMLAD
GTKVVGELVGADTYSDIAVVKISSDNVSTVAEFADSDKLTVGETAIAIGSPLGTEYANSVTQGIVSSLSRTVTMTNDDGE
TISTNAIQTDAAINPGNSGGALINIEGQVIGINSSKISSTSSSGESVEGMGFAIPSNDVVSIINQLEENGQVIRPALGIS
MVNLSDLSTNAIAQLNIPTSVTSGVVVAAVQSGMPAEGNLEQYDVITAIDDQEVTSTSDLQSILYTHSVGDSVKVTFYRG
TDKKTATIELTKTTQDLSSSN

Nucleotide

• Length: 1266 bp

>NTDB_id=40078 SGGBAA2069_RS11725 WP_013643604.1 2354130..2355395(+) (htrA) [Streptococcus gallolyticus subsp. gallolyticus ATCC BAA-2069]
GTGAAAAAAATAAAATTACCAAAATTACCCAAGTTGCCAAAATTTAATTACAAAAATTGGTTAAAACCATTGGGTGTCAT
TTTAGTCGGCTTTATAGCTGGTATCGCAGGTACAATACTCGTCCTAAATATGGCAGGTATTTCAATCACTAACGTCAGTG
GTTCAAGTACAAAAACAACAACAAGTAGCGTAAGCTATTCTAACTCTAACGATACAACAAAAGCTGTGGAAAAAGTTCAA
GACGCAGTTGTATCTGTTATTAACTACAAATCAGACTCGTCGTCTTCTACAAGTGACCTCTACAATCAAATGTTTGGCAA
TGATTCAGACAGTAGTAGCGATTCAAGCTCTACGGATGATTTGACCGTTTACAGTGAAGGTTCTGGGGTTATTTACAAAA
AAGATGGTGATTCTGCTTATGTCGTCACTAACAATCACGTTATTGATGGGGCCGAACAAATTGAAATCATGCTTGCTGAT
GGAACAAAAGTTGTTGGTGAGCTAGTCGGAGCAGATACTTATTCAGATATTGCCGTTGTCAAAATTTCTTCTGACAACGT
ATCTACAGTTGCTGAATTTGCCGATTCTGATAAATTAACTGTCGGTGAAACTGCTATCGCTATTGGTAGCCCACTTGGTA
CTGAATATGCTAACTCTGTAACACAAGGTATTGTCTCAAGTCTTAGCCGTACAGTAACTATGACAAATGATGATGGTGAA
ACTATCTCAACAAATGCTATCCAAACGGATGCAGCGATTAACCCAGGTAACTCTGGTGGTGCTTTAATTAACATTGAAGG
ACAAGTTATCGGTATCAATTCAAGTAAGATTTCATCTACATCAAGTTCTGGTGAATCTGTCGAAGGTATGGGATTTGCCA
TTCCATCTAACGATGTTGTATCCATTATTAACCAATTGGAAGAAAATGGGCAAGTTATCCGCCCAGCACTTGGTATTTCA
ATGGTAAACTTGAGCGACCTTTCAACAAATGCAATTGCTCAACTTAACATTCCAACAAGTGTAACAAGCGGTGTCGTTGT
GGCGGCTGTTCAATCTGGTATGCCAGCTGAAGGTAATCTCGAACAATATGATGTCATCACAGCTATTGACGACCAAGAAG
TAACATCTACTTCAGATCTTCAAAGTATCCTTTATACTCATTCTGTTGGTGACTCTGTCAAAGTAACCTTCTACCGTGGA
ACTGATAAGAAAACAGCCACAATTGAATTAACTAAGACAACACAAGATTTATCTTCCTCAAACTGA

Domains

Predicted by InterproScan.

• Trypsin-like peptidase domain (Trypsin_2) (127-272)

• PDZ domain (PDZ_2) (315-410)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	64.444	96.2	0.62
htrA	Streptococcus gordonii str. Challis substr. CH1	59.804	96.912	0.58
htrA	Streptococcus pneumoniae D39	57.908	97.625	0.565
htrA	Streptococcus pneumoniae TIGR4	57.908	97.625	0.565
htrA	Streptococcus mitis NCTC 12261	57.908	97.625	0.565
htrA	Streptococcus pneumoniae R6	57.908	97.625	0.565
htrA	Streptococcus pneumoniae Rx1	57.908	97.625	0.565