Detailed information NTG0399353

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: GJE17_RS02285
• Genome accession: NZ_CP045930
• Coordinates: 422464..423465 (+)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain AUSMDU00010539
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 417464..428465

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GJE17_RS02260 (GJE17_02260)	-	418138..418821 (-)	684	WP_031488436.1	DUF969 domain-containing protein	-
GJE17_RS02265 (GJE17_02265)	-	419032..419958 (-)	927	WP_002994177.1	glycosyltransferase family 2 protein	-
GJE17_RS02270 (GJE17_02270)	-	420103..420480 (-)	378	WP_002985686.1	VOC family protein	-
GJE17_RS02275 (GJE17_02275)	-	420491..421156 (-)	666	WP_031488435.1	NAD(P)H-dependent oxidoreductase	-
GJE17_RS02280 (GJE17_02280)	-	421205..422290 (-)	1086	WP_031488434.1	aminopeptidase P family protein	-
GJE17_RS02285 (GJE17_02285)	ccpA	422464..423465 (+)	1002	WP_002985680.1	catabolite control protein A	Regulator
GJE17_RS02290 (GJE17_02290)	-	423596..424594 (+)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
GJE17_RS02295 (GJE17_02295)	-	424596..425930 (+)	1335	WP_011284590.1	glycosyltransferase family 4 protein	-
GJE17_RS02300 (GJE17_02300)	thrS	426352..428295 (+)	1944	WP_002985672.1	threonine--tRNA ligase	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=399353 GJE17_RS02285 WP_002985680.1 422464..423465(+) (ccpA) [Streptococcus pyogenes strain AUSMDU00010539]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=399353 GJE17_RS02285 WP_002985680.1 422464..423465(+) (ccpA) [Streptococcus pyogenes strain AUSMDU00010539]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAATTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGGTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACTAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559