Detailed information NTG0396984

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: FOC71_RS01450
• Genome accession: NZ_CP053999
• Coordinates: 269177..271735 (-)
• Length: 852 a.a.
• NCBI ID: WP_003075333.1
• Uniprot ID: -
• Organism: Streptococcus intermedius strain FDAARGOS_769
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 264177..276735

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FOC71_RS01420 (FOC71_01420)	-	264924..265775 (+)	852	WP_003075322.1	ATP-binding protein	-
FOC71_RS01425 (FOC71_01425)	-	266081..266464 (+)	384	WP_268928584.1	ArpU family phage packaging/lysis transcriptional regulator	-
FOC71_RS09780	-	266745..266858 (+)	114	Protein_269	phage terminase small subunit P27 family	-
FOC71_RS01430 (FOC71_01430)	-	266993..267184 (+)	192	WP_003038349.1	type II toxin-antitoxin system HicA family toxin	-
FOC71_RS01435 (FOC71_01435)	-	267221..267601 (+)	381	WP_003038371.1	type II toxin-antitoxin system HicB family antitoxin	-
FOC71_RS01440 (FOC71_01440)	brsR	268140..268580 (+)	441	WP_003075326.1	LytTR family DNA-binding domain-containing protein	Regulator
FOC71_RS01445 (FOC71_01445)	-	268577..269035 (+)	459	WP_003075329.1	DUF3021 domain-containing protein	-
FOC71_RS01450 (FOC71_01450)	hexA	269177..271735 (-)	2559	WP_003075333.1	DNA mismatch repair protein MutS	Machinery gene
FOC71_RS01455 (FOC71_01455)	argR	271898..272338 (-)	441	WP_003075336.1	arginine repressor	-
FOC71_RS01460 (FOC71_01460)	argS	272442..274130 (+)	1689	WP_003075339.1	arginine--tRNA ligase	-
FOC71_RS01465 (FOC71_01465)	nrdI	274182..274637 (-)	456	WP_003075342.1	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	-
FOC71_RS01470 (FOC71_01470)	-	274713..275087 (-)	375	WP_230451274.1	hypothetical protein	-

Sequence

Protein

• Length: 852 a.a.
• Molecular weight: 96162.57 Da
• Isoelectric Point: 4.9357

>NTDB_id=396984 FOC71_RS01450 WP_003075333.1 269177..271735(-) (hexA) [Streptococcus intermedius strain FDAARGOS_769]
MTKEKLSPGMQQYLDIKKDYPDAFLLFRMGDFYELFYEDAINAAQILEIALTSRNKNSEKPIPMAGVPYHSVQQYIDVLI
ESGYKVAIAEQVEDPKKAVGVVKREVVQVITPGTAVDSSKPDSQNNFLVALDKLEDFYGLAYMDVVTGEFQVTTLSDFNM
VCGEIRNLRAREVVLGYELPEAEHQVLANQMNLLLSQVETAFEDVQLLGDDLSRLEYQVAGKLLEYVHQTQLRELSHLKR
VHHYEIKDFLQMDYATMTSLDLTENARTGKKHGSLYWLMDETKTAMGTRLLRRWIQHPLLDKERILKRQDVVQVFLDHFF
ERSDLADSLKGVYDIERLASRVSFGKTNPKDLLQLAATLSNVPQIKGILQGIDHPVLGQLIENLDDIPELANLIQSAIYP
DAPNVITEGNIIQTGFDETLDKYRVVLRDGTSWIADIEAKEKAASGINNLKIDYNKKDGYYFHVTNSQLEHVPSHFFRKA
TLKNSERFGTEELARIEGEMLEAREKSANLEYEIFIRIREEAGKYIKRLQSLAQTLATVDVLQSFAAVAEKQHFVRPEFI
ERPSIEIDKGRHAVVEKVMGAQTYIPNSISMDENVNLQLITGPNMSGKSTYMRQLAIIVIMAQMGSYVSAERAQLPIFDA
IFTRIGAADDLVSGQSTFMVEMMEANHAISQATEHSLILFDELGRGTATYDGMALAQAIIEYIHNRTGAKTLFATHYHEL
TDLSTSLTQLENVHVATVEKDGKVTFLHKIEAGPADKSYGIHVARIAGLPDDLLMRADQILARLEEQANEKPSLNPSNKG
ANDSKENQVSEQISLFTETTESPILDELRQLDIYNMTPMEVMLAIAEMKKHL

Nucleotide

• Length: 2559 bp

>NTDB_id=396984 FOC71_RS01450 WP_003075333.1 269177..271735(-) (hexA) [Streptococcus intermedius strain FDAARGOS_769]
ATGACAAAAGAAAAACTATCTCCGGGAATGCAACAGTATTTAGATATAAAAAAAGATTATCCGGATGCTTTTTTGCTATT
TCGCATGGGAGATTTTTATGAATTATTCTATGAAGATGCGATCAATGCAGCACAGATTTTAGAAATTGCTCTGACTAGCC
GTAATAAAAATTCGGAAAAGCCAATTCCGATGGCAGGAGTTCCCTATCATTCGGTGCAACAATATATTGATGTTTTAATT
GAATCGGGCTATAAAGTAGCGATTGCAGAGCAGGTGGAAGATCCCAAAAAAGCAGTTGGTGTAGTCAAACGTGAGGTGGT
ACAAGTCATCACACCGGGGACAGCCGTTGATTCTTCAAAACCAGATAGTCAAAATAATTTCTTGGTAGCTTTAGATAAGC
TAGAAGATTTCTATGGGCTAGCTTATATGGATGTGGTAACTGGTGAATTTCAGGTGACAACTCTCAGTGACTTTAACATG
GTTTGTGGGGAAATTCGAAATCTACGAGCGCGTGAAGTGGTATTGGGATATGAATTACCTGAAGCAGAGCACCAAGTGTT
GGCAAATCAAATGAATTTGTTATTATCACAGGTGGAAACTGCTTTTGAAGATGTTCAGCTATTAGGAGATGATTTGTCTC
GCCTAGAATATCAAGTAGCTGGGAAACTGTTAGAATATGTTCACCAGACGCAGCTGCGTGAGCTTAGTCACTTAAAGCGA
GTTCATCATTATGAAATTAAAGATTTCTTACAGATGGACTATGCAACTATGACAAGTCTAGATTTAACAGAGAATGCACG
GACGGGGAAGAAGCATGGCAGTCTTTATTGGTTGATGGACGAGACCAAGACAGCTATGGGGACGCGACTTCTAAGAAGAT
GGATCCAGCATCCGTTGCTTGATAAGGAACGGATTCTTAAGCGACAGGATGTCGTACAAGTCTTTTTAGATCATTTTTTT
GAGCGTAGTGATTTGGCAGATAGTCTCAAAGGGGTTTATGATATTGAGCGCTTGGCAAGCCGTGTTTCTTTTGGGAAGAC
AAACCCGAAGGATTTATTGCAGTTGGCGGCAACATTGAGCAATGTCCCTCAGATTAAGGGAATTTTACAAGGAATCGATC
ATCCTGTTTTGGGACAGTTGATTGAAAACTTGGATGATATTCCAGAATTGGCAAACTTGATTCAGTCGGCAATTTATCCT
GATGCTCCAAATGTTATTACGGAAGGGAATATCATTCAAACTGGTTTTGATGAAACCTTAGATAAGTATCGAGTGGTTCT
GCGAGATGGTACGAGCTGGATTGCTGATATTGAAGCGAAAGAAAAAGCAGCTAGTGGGATTAATAATCTAAAAATTGATT
ACAATAAAAAAGATGGTTATTATTTCCATGTTACTAATTCACAGTTGGAGCACGTACCTAGCCACTTTTTCCGAAAAGCA
ACGTTGAAAAATTCAGAACGATTTGGTACAGAGGAATTGGCTCGTATTGAAGGCGAAATGTTGGAAGCGCGTGAAAAATC
GGCCAATTTAGAGTATGAGATTTTTATACGTATTCGGGAAGAAGCTGGCAAATATATCAAACGATTACAATCCTTGGCAC
AAACTCTAGCAACAGTGGATGTATTGCAGAGTTTTGCAGCAGTTGCTGAAAAGCAACACTTTGTACGCCCAGAATTTATT
GAACGTCCTTCCATTGAAATCGATAAGGGACGGCATGCAGTTGTAGAAAAGGTTATGGGCGCACAAACTTATATTCCGAA
TAGTATTTCAATGGACGAGAATGTCAATCTTCAGCTAATTACAGGTCCAAATATGAGTGGGAAGTCAACCTATATGCGTC
AATTAGCGATTATTGTTATCATGGCGCAAATGGGTTCCTATGTTTCAGCTGAACGTGCTCAATTACCAATTTTTGATGCC
ATCTTCACTCGAATTGGTGCAGCAGATGACTTGGTATCTGGACAATCAACCTTTATGGTAGAAATGATGGAAGCAAATCA
TGCTATTTCTCAAGCGACTGAACACTCTCTTATTCTTTTTGATGAGTTGGGAAGAGGAACAGCAACATATGATGGGATGG
CTCTTGCTCAGGCGATTATTGAATATATCCACAATCGAACAGGAGCAAAGACCCTTTTTGCTACACACTATCATGAGTTG
ACAGACTTGTCAACTAGCTTGACACAGTTAGAAAATGTTCATGTAGCAACTGTAGAAAAAGATGGGAAAGTGACCTTCCT
TCATAAGATTGAAGCTGGTCCTGCAGATAAATCTTATGGGATTCATGTCGCAAGAATTGCAGGTTTACCAGATGATTTGT
TGATGAGAGCCGACCAGATATTAGCAAGACTAGAAGAACAAGCAAATGAGAAACCATCTCTCAATCCCTCTAATAAAGGA
GCTAATGATAGTAAAGAAAATCAAGTATCTGAGCAGATATCTTTATTCACAGAAACAACTGAATCACCTATTTTAGATGA
ACTACGTCAGTTGGATATTTATAATATGACCCCAATGGAAGTGATGCTAGCTATAGCTGAGATGAAAAAACATCTCTGA

Domains

Predicted by InterProScan.

• MutS domain III (MutS_III) (255-546)

• MutS domain II (MutS_II) (126-239)

• MutS domain I (MutS_I) (8-118)

• MutS domain V (MutS_V) (599-785)

• MutS family domain IV (MutS_IV) (415-505)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	75.235	100	0.752
mutS	Pseudomonas stutzeri strain ATCC 17587	36.543	100	0.37