Detailed information NTG0390296

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: FSA31_RS04680
• Genome accession: NZ_CP044492
• Coordinates: 952239..953081 (+)
• Length: 280 a.a.
• NCBI ID: WP_002262865.1
• Uniprot ID: -
• Organism: Streptococcus mutans strain T8
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 947239..958081

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FSA31_RS04650 (FSA31_0920)	-	947922..948884 (+)	963	WP_002284249.1	iron chelate uptake ABC transporter family permease subunit	-
FSA31_RS04655 (FSA31_0921)	-	948881..949852 (+)	972	WP_002284248.1	iron chelate uptake ABC transporter family permease subunit	-
FSA31_RS04660 (FSA31_0922)	-	949849..950655 (+)	807	WP_002284247.1	ATP-binding cassette domain-containing protein	-
FSA31_RS04665 (FSA31_0923)	-	950703..951719 (+)	1017	WP_002284246.1	siderophore ABC transporter substrate-binding protein	-
FSA31_RS04670 (FSA31_0924)	-	951791..952072 (+)	282	WP_002262863.1	hypothetical protein	-
FSA31_RS04680 (FSA31_0926)	dprA	952239..953081 (+)	843	WP_002262865.1	DNA-processing protein DprA	Machinery gene
FSA31_RS04685 (FSA31_0927)	topA	953176..955293 (+)	2118	WP_002272153.1	type I DNA topoisomerase	-
FSA31_RS04690 (FSA31_0928)	trmFO	955660..956994 (+)	1335	WP_002262867.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-

Sequence

Protein

• Length: 280 a.a.
• Molecular weight: 31332.27 Da
• Isoelectric Point: 9.1954

>NTDB_id=390296 FSA31_RS04680 WP_002262865.1 952239..953081(+) (dprA) [Streptococcus mutans strain T8]
MDNFQLFKLKKAGLTNLNILNIIDYEERTQKSLSLRDMAVVSKNKKPLIFMEHYKNLDSKALRKEFNRFPSLSILDKEYP
LELKNIYNPPVLLFYQGDLDLLARPKLAVVGSRNASQMGVAAVKKIIQDLSKQFVIISGLARGIDTAAHLASLKSGGATI
AVIGTGLDVHYPKENRRLQDYIAKNHLLLSEYEAQSQPLKYHFPERNRIIAGLSQGVMVAEAKIRSGSLITCERAMEEGR
DVFVVPGNILDGQSEGCHHLIQEGAKCITSGFDILNEFNF

Nucleotide

• Length: 843 bp

>NTDB_id=390296 FSA31_RS04680 WP_002262865.1 952239..953081(+) (dprA) [Streptococcus mutans strain T8]
ATGGATAATTTTCAACTATTTAAACTTAAAAAAGCTGGTCTAACAAATCTGAATATCTTAAATATTATTGATTATGAAGA
GAGGACACAAAAATCCTTGTCTCTTCGTGATATGGCTGTTGTTTCCAAAAATAAAAAGCCTTTAATTTTTATGGAACATT
ACAAGAATCTTGATAGCAAAGCATTACGCAAAGAATTTAATCGTTTTCCTTCTTTATCCATTTTGGACAAAGAATATCCC
TTGGAACTTAAAAATATTTATAATCCGCCTGTTCTTCTATTTTATCAGGGAGACTTAGACTTACTAGCTCGGCCTAAATT
AGCAGTAGTTGGTTCTCGCAACGCCAGTCAAATGGGAGTAGCTGCTGTTAAAAAGATCATACAAGACTTAAGTAAGCAAT
TTGTTATTATTAGCGGTTTAGCGCGTGGTATTGATACTGCAGCACATTTAGCAAGTCTTAAAAGCGGTGGAGCAACAATT
GCGGTCATCGGTACTGGACTAGATGTTCATTATCCTAAAGAAAATCGAAGACTGCAGGATTATATTGCAAAGAATCATTT
GCTCTTATCAGAATATGAAGCACAGAGTCAACCTCTTAAGTATCATTTTCCTGAGCGGAACCGCATTATTGCTGGGTTAT
CTCAAGGTGTTATGGTAGCAGAAGCAAAAATTCGTTCGGGTAGTCTGATTACTTGTGAACGTGCTATGGAAGAAGGACGC
GATGTTTTTGTTGTACCAGGAAATATTTTAGACGGCCAGTCAGAAGGATGCCATCACCTGATTCAAGAAGGAGCAAAATG
CATTACATCAGGCTTTGATATTTTAAATGAGTTTAACTTTTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (72-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	100	100	1
dprA/cilB/dalA	Streptococcus mitis SK321	63.214	100	0.632
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	63.214	100	0.632
dprA/cilB/dalA	Streptococcus pneumoniae D39	63.214	100	0.632
dprA/cilB/dalA	Streptococcus pneumoniae R6	63.214	100	0.632
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	63.214	100	0.632
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	62.857	100	0.629
dprA	Lactococcus lactis subsp. cremoris KW2	58.273	99.286	0.579
dprA	Legionella pneumophila strain ERS1305867	44.77	85.357	0.382
dprA	Staphylococcus aureus N315	38.258	94.286	0.361