Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE   Type   Machinery gene
Locus tag   G6Z52_RS00680 Genome accession   NZ_CP049187
Coordinates   104136..104420 (+) Length   94 a.a.
NCBI ID   WP_002987779.1    Uniprot ID   A0A0H2USY2
Organism   Streptococcus pyogenes strain TSPY1687     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 99136..109420
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  G6Z52_RS00655 (G6Z52_00650) - 101082..101447 (+) 366 WP_002986560.1 DUF1033 family protein -
  G6Z52_RS00660 (G6Z52_00655) comGA 101540..102478 (+) 939 WP_002987773.1 competence type IV pilus ATPase ComGA Machinery gene
  G6Z52_RS00665 (G6Z52_00660) comGB 102414..103448 (+) 1035 WP_223845212.1 competence type IV pilus assembly protein ComGB Machinery gene
  G6Z52_RS00670 (G6Z52_00665) comGC 103450..103776 (+) 327 WP_002986552.1 competence type IV pilus major pilin ComGC Machinery gene
  G6Z52_RS00675 (G6Z52_00670) comGD 103751..104179 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD Machinery gene
  G6Z52_RS00680 (G6Z52_00675) comGE 104136..104420 (+) 285 WP_002987779.1 competence type IV pilus minor pilin ComGE Machinery gene
  G6Z52_RS00685 (G6Z52_00680) comGF 104413..104847 (+) 435 WP_002987783.1 competence type IV pilus minor pilin ComGF Machinery gene
  G6Z52_RS00690 (G6Z52_00685) comGG 104831..105157 (+) 327 WP_002987787.1 competence type IV pilus minor pilin ComGG -
  G6Z52_RS00695 (G6Z52_00690) comGH 105255..106208 (+) 954 WP_002987790.1 class I SAM-dependent methyltransferase Machinery gene
  G6Z52_RS00700 (G6Z52_00695) - 106267..107463 (+) 1197 WP_002987791.1 acetate kinase -
  G6Z52_RS00705 (G6Z52_00700) - 107650..107958 (+) 309 WP_002987795.1 hypothetical protein -
  G6Z52_RS00710 (G6Z52_00705) proC 108041..108811 (-) 771 WP_002986527.1 pyrroline-5-carboxylate reductase -

Sequence

Protein


Download         Length: 94 a.a.        Molecular weight: 10672.62 Da        Isoelectric Point: 8.9043

>NTDB_id=372805 G6Z52_RS00680 WP_002987779.1 104136..104420(+) (comGE) [Streptococcus pyogenes strain TSPY1687]
MGIIKKQVKAYIALESMIATGILFSIVILVLSSLQQSQAALTYYRKQQEKLNLALMAVQTRTKEMTLNGCHITILRTDRY
ISIHDDEGEVMKIE

Nucleotide


Download         Length: 285 bp        

>NTDB_id=372805 G6Z52_RS00680 WP_002987779.1 104136..104420(+) (comGE) [Streptococcus pyogenes strain TSPY1687]
GTGGGAATTATCAAAAAACAAGTCAAAGCTTACATAGCCCTTGAAAGTATGATTGCAACAGGCATCCTCTTTAGTATTGT
CATTCTCGTCTTAAGCAGTTTACAGCAGAGTCAGGCTGCTCTAACGTACTATCGAAAGCAGCAAGAAAAGCTTAATCTAG
CCTTGATGGCAGTACAAACTAGAACTAAAGAGATGACATTGAATGGTTGTCATATTACTATTTTACGTACGGATAGATAC
ATTAGTATTCACGATGACGAAGGAGAAGTGATGAAGATTGAGTAA

Domains

Predicted by InterProScan.

Type II secretory pathway pseudopilin (ComGE)

(12-93)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2USY2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Lactococcus lactis subsp. cremoris KW2

38.298

100

0.383