Detailed information NTG0035918

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: I33_RS00580
• Genome accession: NC_017195
• Coordinates: 107337..108419 (+)
• Length: 360 a.a.
• NCBI ID: WP_003225736.1
• Uniprot ID: P37573
• Organism: Bacillus subtilis subsp. subtilis str. RO-NN-1
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 102337..113419

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I33_RS00565 (I33_0115)	mcsB	102345..103436 (+)	1092	WP_003235007.1	protein arginine kinase	-
I33_RS00570 (I33_0116)	clpC	103433..105865 (+)	2433	WP_014475592.1	ATP-dependent protease ATP-binding subunit ClpC	Regulator
I33_RS00575 (I33_0117)	radA/sms	105957..107333 (+)	1377	WP_014475593.1	DNA repair protein RadA	Machinery gene
I33_RS00580 (I33_0118)	disA	107337..108419 (+)	1083	WP_003225736.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
I33_RS00585 (I33_0119)	yacL	108536..109636 (+)	1101	WP_003235014.1	PIN/TRAM domain-containing protein	-
I33_RS00590 (I33_0120)	ispD	109651..110349 (+)	699	WP_003235019.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-
I33_RS00595 (I33_0121)	ispF	110342..110818 (+)	477	WP_014475594.1	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	-
I33_RS00600 (I33_0122)	gltX	110909..112360 (+)	1452	WP_014475595.1	glutamate--tRNA ligase	-
I33_RS00610 (I33_0124)	cysE	112662..113315 (+)	654	WP_003225749.1	serine O-acetyltransferase	-

Sequence

Protein

• Length: 360 a.a.
• Molecular weight: 40734.29 Da
• Isoelectric Point: 5.7343

>NTDB_id=35918 I33_RS00580 WP_003225736.1 107337..108419(+) (disA) [Bacillus subtilis subsp. subtilis str. RO-NN-1]
MEKEKKGAKHELDLSSILQFVAPGTPLRAGMENVLRANTGGLIVVGYNDKVKEVVDGGFHINTAFSPAHLYELAKMDGAI
ILSDSGQKILYANTQLMPDATISSSETGMRHRTAERVAKQTGCLVIAISERRNVITLYQENMKYTLKDIGFILTKANQAI
QTLEKYKTILDKTINALNALEFEELVTFSDVLSVMHRYEMVLRIKNEINMYIKELGTEGHLIKLQVIELITDMEEEAALF
IKDYVKEKIKDPFVLLKELQDMSSYDLLDDSIVYKLLGYPASTNLDDYVLPRGYRLLNKIPRLPMPIVENVVEAFGVLPR
IIEASAEELDEVEGIGEVRAQKIKKGLKRLQEKHYLDRQL

Nucleotide

• Length: 1083 bp

>NTDB_id=35918 I33_RS00580 WP_003225736.1 107337..108419(+) (disA) [Bacillus subtilis subsp. subtilis str. RO-NN-1]
ATGGAAAAAGAGAAAAAAGGGGCGAAACACGAGTTAGACCTGTCATCTATATTGCAGTTTGTTGCTCCGGGTACACCGCT
CAGAGCGGGGATGGAAAACGTCTTGAGAGCAAATACAGGCGGTCTGATTGTTGTTGGATATAATGATAAAGTAAAAGAAG
TGGTGGACGGCGGCTTTCACATAAACACGGCTTTTTCTCCGGCGCATTTATATGAGCTGGCTAAAATGGATGGAGCGATC
ATTTTAAGTGATTCGGGTCAAAAGATCCTCTATGCGAATACTCAGCTTATGCCGGATGCCACAATTTCTTCATCAGAAAC
AGGAATGCGGCACAGAACTGCCGAAAGAGTAGCTAAGCAAACTGGCTGTCTTGTGATCGCTATTTCCGAAAGAAGAAATG
TCATAACGTTATATCAGGAAAACATGAAGTATACACTAAAAGACATAGGATTTATTTTAACCAAGGCGAACCAAGCCATT
CAAACACTTGAAAAATATAAGACAATCCTCGATAAAACGATTAATGCACTGAACGCGTTAGAGTTTGAGGAACTTGTTAC
CTTCAGTGATGTCTTGTCTGTCATGCATCGTTATGAAATGGTATTGAGAATCAAAAACGAAATTAATATGTACATCAAAG
AGCTGGGGACAGAAGGGCATCTGATCAAACTGCAAGTCATTGAATTGATTACGGATATGGAAGAAGAGGCTGCTTTATTT
ATTAAGGACTATGTAAAAGAAAAAATTAAAGATCCGTTTGTTCTCTTGAAGGAGCTGCAGGATATGTCCAGTTATGATCT
GCTGGATGATTCCATTGTGTATAAGCTTCTCGGTTACCCTGCTTCTACTAATCTTGATGATTATGTATTGCCGAGAGGAT
ACAGGCTGTTAAATAAGATACCGCGTCTTCCGATGCCGATTGTTGAAAATGTTGTAGAAGCATTTGGAGTCCTACCAAGG
ATTATTGAGGCGAGTGCAGAAGAATTAGATGAAGTAGAAGGAATCGGTGAAGTACGAGCCCAAAAAATCAAAAAAGGATT
AAAACGCCTGCAAGAGAAGCATTATTTAGACAGACAACTGTGA

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (29-141)

• DisA bacterial checkpoint controller linker region (DisA-linker) (146-284)

3D structure

• AlphaFold DB: P37573

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	100	100	1