Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   ES276_RS10925 Genome accession   NZ_CP038252
Coordinates   886086..887099 (-) Length   337 a.a.
NCBI ID   WP_307772067.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901936     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 881086..892099
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ES276_RS04565 (ES276_04905) - 881352..881690 (+) 339 WP_000876675.1 LytTR family DNA-binding domain-containing protein -
  ES276_RS04570 (ES276_04910) comE/blpR 881695..882432 (+) 738 WP_001219120.1 LytTR family DNA-binding domain-containing protein Regulator
  ES276_RS04575 (ES276_04915) - 882446..883786 (+) 1341 WP_001017646.1 sensor histidine kinase -
  ES276_RS04580 (ES276_04920) blpC 883857..883985 (-) 129 WP_000358815.1 quorum-sensing system pheromone BlpC -
  ES276_RS04585 (ES276_04925) - 884042..885412 (-) 1371 WP_001069077.1 bacteriocin secretion accessory protein -
  ES276_RS10920 (ES276_04930) comA/nlmT 885423..886070 (-) 648 WP_322349254.1 ATP-binding cassette domain-containing protein Regulator
  ES276_RS10925 (ES276_04935) comA/nlmT 886086..887099 (-) 1014 WP_307772067.1 ABC transporter transmembrane domain-containing protein Regulator
  ES276_RS10930 (ES276_04940) comA/nlmT 886993..887580 (-) 588 WP_000205166.1 cysteine peptidase family C39 domain-containing protein Regulator
  ES276_RS04595 (ES276_04945) blpI 887860..888057 (+) 198 WP_001093259.1 bacteriocin-like peptide BlpI -
  ES276_RS04600 (ES276_04955) blpJ 888524..888793 (+) 270 WP_001093248.1 bacteriocin-like peptide BlpJ -
  ES276_RS04605 (ES276_04960) blpU 888862..889092 (+) 231 WP_000379967.1 bacteriocin-like peptide BlpU -
  ES276_RS04610 (ES276_04965) - 889095..889214 (+) 120 WP_000346296.1 PncF family bacteriocin immunity protein -
  ES276_RS04615 (ES276_04970) - 889511..889675 (+) 165 WP_000727118.1 hypothetical protein -
  ES276_RS04620 (ES276_04975) - 889672..890076 (+) 405 WP_000846943.1 hypothetical protein -
  ES276_RS04625 (ES276_04980) - 890279..891083 (+) 805 WP_100214365.1 IS5 family transposase -
  ES276_RS04630 (ES276_04985) blpM 891233..891487 (+) 255 WP_000379879.1 two-peptide bacteriocin subunit BlpM -
  ES276_RS04635 (ES276_04990) blpN 891503..891706 (+) 204 WP_001099492.1 two-peptide bacteriocin subunit BlpN -
  ES276_RS04640 (ES276_05000) cipB 891950..892099 (+) 150 WP_001818346.1 bacteriocin-like peptide BlpO Regulator

Sequence

Protein


Download         Length: 337 a.a.        Molecular weight: 38280.73 Da        Isoelectric Point: 5.1196

>NTDB_id=352671 ES276_RS10925 WP_307772067.1 886086..887099(-) (comA/nlmT) [Streptococcus pneumoniae strain TVO_1901936]
MIFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSI
DVILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLISIPIYM
FIIFSFMKPFEKMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTK
LVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHF
LMGDIEFDDLSYKYGFG

Nucleotide


Download         Length: 1014 bp        

>NTDB_id=352671 ES276_RS10925 WP_307772067.1 886086..887099(-) (comA/nlmT) [Streptococcus pneumoniae strain TVO_1901936]
CTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTTC
TTACTATCTCCAAGGAATCTTGGATGAATACATTCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGG
TTATCACCTATATCCTCCAACAAGTCATGAGCTTCTCCAGAGATTATCTCCTAACCGTTCTGAGTCAGAGATTAAGTATT
GATGTGATTTTATCCTATATTCGCCATATTTTTGAACTTCCCATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCAT
TTCACGATTCACAGATGCTAACTCTATTATAGATGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTC
TGATTCTTGTAGGAGGCGTCTTACTGGCACAAAACCCTAATCTCTTCCTTCTTTCTCTTATTTCCATTCCTATATACATG
TTCATCATCTTTTCTTTTATGAAACCTTTCGAAAAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGC
CATTATCGAAGATATCAACGGGATTGAAACTATAAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCG
AATTTGTAGATTATTTGGAAAAATCCTTTAAGCTCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAA
TTAGTTCTGAATATCCTTATCCTATGGTTTGGCGCTCAATTAGTCATGTCAAGTAAAATTTCTATCGGTCAGCTGATTAC
CTTTAACACACTTTTTTCTTACTTTACAACTCCTATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGG
TCGCTAATAACCGTTTGAACGAAGTCTATCTAGTCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTTCATTCACATTTT
TTGATGGGCGATATTGAATTTGATGACCTTTCTTATAAGTATGGTTTTGGATGA

Domains

Predicted by InterproScan.

ABC transporter transmembrane region (ABC_membrane)

(10-279)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

72.997

100

0.73
  comA Streptococcus gordonii str. Challis substr. CH1

67.16

100

0.674
  comA Streptococcus mitis NCTC 12261

66.766

100

0.668
  comA Streptococcus pneumoniae Rx1

66.469

100

0.665
  comA Streptococcus pneumoniae D39

66.469

100

0.665
  comA Streptococcus pneumoniae R6

66.469

100

0.665
  comA Streptococcus pneumoniae TIGR4

66.172

100

0.662
  comA Streptococcus mitis SK321

66.172

100

0.662

Multiple sequence alignment