Detailed information NTG0352630

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: GE024_RS09700
• Genome accession: NZ_CP046521
• Coordinates: 1961041..1961781 (-)
• Length: 246 a.a.
• NCBI ID: WP_093999364.1
• Uniprot ID: -
• Organism: Streptococcus canis strain HL_100
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1956041..1966781

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GE024_RS09670 (GE024_09710)	-	1956468..1956854 (-)	387	WP_093999452.1	DUF3021 domain-containing protein	-
GE024_RS11260	-	1956874..1957095 (-)	222	WP_223824837.1	LytTR family DNA-binding domain-containing protein	-
GE024_RS09680 (GE024_09720)	jag	1957671..1958579 (-)	909	WP_093999453.1	RNA-binding cell elongation regulator Jag/EloR	-
GE024_RS09685 (GE024_09725)	-	1958591..1959418 (-)	828	WP_093999454.1	YidC/Oxa1 family membrane protein insertase	-
GE024_RS09690 (GE024_09730)	rnpA	1959384..1959743 (-)	360	WP_093999455.1	ribonuclease P protein component	-
GE024_RS09695 (GE024_09735)	tnpA	1960126..1960590 (-)	465	Protein_1859	IS200/IS605 family transposase	-
GE024_RS09700 (GE024_09740)	comE/blpR	1961041..1961781 (-)	741	WP_093999364.1	LytTR family DNA-binding domain-containing protein	Regulator
GE024_RS09705 (GE024_09745)	-	1961785..1963068 (-)	1284	WP_003045486.1	sensor histidine kinase	-
GE024_RS09710 (GE024_09750)	-	1963069..1964412 (-)	1344	WP_093999363.1	GHKL domain-containing protein	-
GE024_RS09715 (GE024_09755)	gltX	1964834..1966282 (-)	1449	WP_003045490.1	glutamate--tRNA ligase	-

Sequence

Protein

• Length: 246 a.a.
• Molecular weight: 28879.20 Da
• Isoelectric Point: 4.8525

>NTDB_id=352630 GE024_RS09700 WP_093999364.1 1961041..1961781(-) (comE/blpR) [Streptococcus canis strain HL_100]
MMNIFILEDDFIQQTRIESVVVAILEATKIPCNQLEVFSNPQKLFESIQERGDHQLYFLDIEIGDEARRGLELAVDIRQK
DPNAVIVFVTTHSEFAPISFKYKVSALDFIDKAADNEQFKEQIEDCIRYTYEMMSSRESEDIFLFETPQTRLKLPYKDIL
YFATATTPHKVCLWTQTERLEFYGNLSEIQAVAPKLFLCHRSYLVNLDRVVRIDKAKQLLYFENGDSCMVSRLKMKCLFE
KWESLH

Nucleotide

• Length: 741 bp

>NTDB_id=352630 GE024_RS09700 WP_093999364.1 1961041..1961781(-) (comE/blpR) [Streptococcus canis strain HL_100]
ATGATGAATATTTTTATTCTTGAAGATGATTTTATCCAGCAGACACGCATTGAGTCCGTGGTGGTGGCTATCTTGGAAGC
AACTAAAATCCCTTGTAATCAGCTAGAAGTATTTTCAAATCCCCAAAAATTATTTGAGAGCATTCAAGAAAGAGGAGACC
ATCAACTGTATTTTTTAGATATTGAGATTGGTGATGAGGCTCGTCGTGGGCTTGAGTTAGCAGTAGATATCCGCCAAAAA
GATCCCAATGCAGTGATTGTTTTTGTGACCACTCATTCTGAATTTGCACCTATTTCCTTCAAATATAAGGTTTCTGCTCT
GGATTTTATTGATAAGGCGGCAGATAATGAGCAGTTCAAGGAACAAATTGAAGACTGTATTCGCTACACCTATGAGATGA
TGTCAAGTCGGGAATCTGAAGATATATTTTTGTTTGAAACGCCCCAGACCAGATTAAAGCTACCCTACAAAGATATTTTA
TACTTTGCCACAGCAACTACGCCCCACAAGGTGTGTTTGTGGACCCAGACGGAGAGACTGGAATTCTATGGTAATTTATC
TGAAATACAGGCCGTTGCTCCTAAGCTTTTCTTATGTCATAGGTCCTACTTGGTCAATCTTGATAGGGTTGTCCGCATTG
ACAAGGCCAAGCAGCTGCTTTATTTTGAAAATGGGGATTCCTGCATGGTTTCACGTTTGAAAATGAAATGCCTTTTTGAA
AAATGGGAGTCCCTTCATTAA

Domains

Predicted by InterProScan.

• Response regulator receiver domain (Response_reg) (4-123)

• LytTr DNA-binding domain (LytTR) (152-242)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	48.117	97.154	0.467
comE/comE1	Streptococcus equinus JB1	42.437	96.748	0.411
comE/comE2	Streptococcus equinus JB1	40.408	99.593	0.402
comE/comE2	Streptococcus gordonii strain NCTC7865	38.934	99.187	0.386
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	38.934	99.187	0.386
comE	Streptococcus mitis NCTC 12261	36.929	97.967	0.362
comE	Streptococcus pneumoniae Rx1	36.929	97.967	0.362
comE	Streptococcus pneumoniae D39	36.929	97.967	0.362
comE	Streptococcus pneumoniae R6	36.929	97.967	0.362
comE	Streptococcus pneumoniae TIGR4	36.929	97.967	0.362
comE	Streptococcus mitis SK321	36.929	97.967	0.362