Detailed information NTG0352558

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: ES300_RS08545
• Genome accession: NZ_CP038251
• Coordinates: 1697628..1698695 (-)
• Length: 355 a.a.
• NCBI ID: WP_000159554.1
• Uniprot ID: A0A062WMA1
• Organism: Streptococcus pneumoniae strain TVO_1901944
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1692628..1703695

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ES300_RS08520 (ES300_08970)	treR	1692800..1693510 (+)	711	WP_000760673.1	trehalose operon repressor	Regulator
ES300_RS08525 (ES300_08975)	-	1693543..1694346 (-)	804	WP_000202630.1	ABC transporter ATP-binding protein	-
ES300_RS08530 (ES300_08980)	-	1694359..1695252 (-)	894	WP_001012092.1	ABC transporter permease	-
ES300_RS08535 (ES300_08985)	-	1695264..1696073 (-)	810	WP_001850051.1	ABC transporter substrate-binding protein	-
ES300_RS08540 (ES300_08990)	amiF	1696691..1697617 (-)	927	WP_001291293.1	ATP-binding cassette domain-containing protein	Regulator
ES300_RS08545 (ES300_08995)	amiE	1697628..1698695 (-)	1068	WP_000159554.1	ABC transporter ATP-binding protein	Regulator
ES300_RS08550 (ES300_09000)	amiD	1698704..1699630 (-)	927	WP_000103700.1	oligopeptide ABC transporter permease OppC	Regulator
ES300_RS08555 (ES300_09005)	amiC	1699630..1701126 (-)	1497	WP_000759903.1	ABC transporter permease	Regulator
ES300_RS08560 (ES300_09010)	amiA3	1701193..1703172 (-)	1980	WP_000742232.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39490.09 Da
• Isoelectric Point: 4.8727

>NTDB_id=352558 ES300_RS08545 WP_000159554.1 1697628..1698695(-) (amiE) [Streptococcus pneumoniae strain TVO_1901944]
MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDL
TALSSHKDWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAK
TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD

Nucleotide

• Length: 1068 bp

>NTDB_id=352558 ES300_RS08545 WP_000159554.1 1697628..1698695(-) (amiE) [Streptococcus pneumoniae strain TVO_1901944]
ATGACAAAAGAAAAAAATGTAATTTTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGACAAAGTATTGACAGC
CATTCGCGGCGTTTCCCTTGAACTAGTCGAAGGAGAAGTATTAGCCTTGGTAGGTGAGTCAGGATCAGGTAAATCTGTTT
TGACAAAGACCTTCACAGGTATGCTCGAAGAAAATGGTCGCATTGCCCAAGGTAGTATTGACTACCGTGGTCAGGACTTG
ACAGCTTTATCTTCTCACAAGGATTGGGAACAAATTCGTGGTGCTAAGATTGCGACTATCTTCCAGGACCCAATGACTAG
TTTGGACCCCATTAAAACAATTGGTAGTCAGATTACAGAAGTTATTGTAAAACACCAAGGAAAAACAGCTAAAGAAGCGA
AAGAATTGGCCATTGACTACATGAATAAGGTTGGCATTCCAGACGCAGATAGACGTTTTAATGAATACCCATTCCAATAT
TCTGGAGGAATGCGTCAACGTATCGTTATTGCGATTGCCCTTGCCTGCCGACCTGATGTCTTGATCTGTGATGAGCCAAC
AACTGCCTTGGATGTAACTATTCAAGCTCAGATTATTGATTTGCTAAAATCTTTACAAAACGAGTATCATTTCACAACAA
TCTTTATTACCCACGACCTTGGTGTGGTGGCAAGTATTGCGGATAAGGTAGCGGTTATGTATGCAGGAGAAATCGTTGAG
TATGGAACGGTTGAGGAAGTCTTCTATGACCCTCGCCATCCATATACATGGAGTCTCTTGTCTAGCTTGCCTCAGCTTGC
TGATGATAAAGGGGATCTTTACTCAATCCCAGGAACACCTCCGTCACTTTATACTGACCTGAAAGGGGATGCTTTTGCCT
TGCGTTCTGACTACGCAATGCAGATTGACTTCGAACAAAAAGCTCCTCAATTCTCAGTATCAGAGACACATTGGGCTAAA
ACTTGGCTTCTTCATGAGGATGCTCCAAAAGTAGAAAAACCAGCTGTGATTGCAAATCTCCATGATAAGATCCGTGAAAA
AATGGGATTTGCCCATCTGGCTGACTAG

Domains

Predicted by InterproScan.

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

• ABC transporter (ABC_tran) (29-187)

3D structure

• AlphaFold DB: A0A062WMA1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	88.169	100	0.882
amiE	Streptococcus thermophilus LMG 18311	86.479	100	0.865
amiE	Streptococcus thermophilus LMD-9	86.479	100	0.865
oppD	Streptococcus mutans UA159	54.545	99.155	0.541