Detailed information NTG0034676

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: SSUBM407_RS06390
• Genome accession: NC_012926
• Coordinates: 1299929..1302166 (-)
• Length: 745 a.a.
• NCBI ID: WP_012775640.1
• Uniprot ID: A0A0H3MWC1
• Organism: Streptococcus suis BM407
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1294929..1307166

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SSUBM407_RS06365 (SSUBM407_1207)	tmk	1295034..1295672 (-)	639	WP_012775041.1	dTMP kinase	-
SSUBM407_RS06370 (SSUBM407_1208)	-	1295847..1296713 (+)	867	WP_002935357.1	YitT family protein	-
SSUBM407_RS06375 (SSUBM407_1209)	-	1296750..1298021 (-)	1272	WP_012775639.1	toxic anion resistance protein	-
SSUBM407_RS06380 (SSUBM407_1210)	-	1298027..1298854 (-)	828	WP_011922194.1	hypothetical protein	-
SSUBM407_RS06385 (SSUBM407_1211)	-	1298948..1299604 (-)	657	WP_011922763.1	CBS domain-containing protein	-
SSUBM407_RS10770 (SSUBM407_1212)	-	1299787..1299912 (-)	126	Protein_1222	IS982 family transposase	-
SSUBM407_RS06390 (SSUBM407_1213)	comEC/celB	1299929..1302166 (-)	2238	WP_012775640.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
SSUBM407_RS06395 (SSUBM407_1214)	-	1302150..1302812 (-)	663	WP_011922190.1	helix-hairpin-helix domain-containing protein	-
SSUBM407_RS06400 (SSUBM407_1215)	-	1302875..1303624 (-)	750	WP_012775039.1	lysophospholipid acyltransferase family protein	-
SSUBM407_RS06405 (SSUBM407_1216)	-	1303771..1305216 (+)	1446	WP_011922188.1	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	-
SSUBM407_RS06410 (SSUBM407_1217)	-	1305368..1306153 (+)	786	WP_011922762.1	ABC transporter ATP-binding protein	-
SSUBM407_RS06415 (SSUBM407_1218)	-	1306166..1307095 (+)	930	WP_012775038.1	ABC transporter substrate-binding protein	-

Sequence

Protein

• Length: 745 a.a.
• Molecular weight: 83979.95 Da
• Isoelectric Point: 7.8195

>NTDB_id=34676 SSUBM407_RS06390 WP_012775640.1 1299929..1302166(-) (comEC/celB) [Streptococcus suis BM407]
MSRLSKLPCQPVHLAVLAVAAYFAVHSFSLLTMCLLSLVLAVFGVRQGKTVFLKTLPLLTLCGLFFGCQKVQWERAAQSA
PEQVTTVQVIPDTIDINGDSLSFRGRADGQNYQVFYKLTSQEEQTYFQNLADLVQLEVEAEVSLPAGQRNFKGFDYQAYL
KTQGIYRTVKLTAIKKIVPVQSWNVFDWLSTWRRQALVYVKTNFPAPMSHYMTGLLFGELDSDFDQMSDLYSSLGIIHLF
ALSGMQVGFFIDKFRWILLRLGLTKETVDKLQIPFSLVYAGLTGFSVSVVRSLVQKILGNLGLRKLDNFAVTVFICLLIL
PRFLLTAGGVLTFTYAFLLTVFDFEDLGQVKKAAVESLSISLGILPVLMTYFYAFQPLSILLTFVFSFVFDVLLLPGLSV
IFLLSPVVKMTWINGFFVFMEKIIVWVADLGLRPWILGKPSELVLLLLLVSLFLLYDFHRRKKWLLGLSLVLALLFFITK
HPLENEVTVLDIGQGDSIFLRDMRGRTVLIDVGGRVDFAAKEAWQERSRQANAERTLIPYLHSRGVDRIDSLVLTHTDTD
HVGDVLEVAKQVQIGRIVVSPGSLTVPDFVATLKKINVPVHVVKVGDRLPIFDSYLEVLYPDGTGDGGNNDSIVLYGRLL
ETNFLFTGDLEQGELDLIETYPNLPVDVLKAGHHGSKGSSYPEFLDHIGAKIALVSAGENNRYKHPHQETLERFDSRNIQ
VYRTDQQGAIRFRGWKEWKIETVRR

Nucleotide

• Length: 2238 bp

>NTDB_id=34676 SSUBM407_RS06390 WP_012775640.1 1299929..1302166(-) (comEC/celB) [Streptococcus suis BM407]
ATGTCACGGTTGAGTAAGCTCCCCTGCCAGCCCGTTCACCTGGCAGTCTTGGCGGTGGCAGCTTACTTTGCAGTCCACTC
TTTTTCCCTCTTGACAATGTGCCTGCTCAGCTTGGTGTTAGCTGTCTTTGGTGTTCGGCAAGGTAAGACAGTTTTCCTCA
AAACGCTGCCGCTTCTAACCCTGTGTGGTCTCTTTTTCGGATGCCAAAAGGTCCAATGGGAGCGGGCAGCTCAGTCAGCC
CCAGAGCAAGTGACGACTGTGCAGGTCATTCCAGATACCATAGACATCAATGGCGACAGCTTGTCTTTTCGTGGTCGGGC
TGATGGACAAAACTATCAGGTTTTCTACAAATTAACCAGTCAGGAGGAGCAGACCTATTTTCAAAATCTGGCAGACCTGG
TCCAGCTAGAAGTGGAAGCAGAGGTCAGCCTGCCAGCTGGTCAGCGGAATTTCAAGGGCTTTGACTATCAGGCCTATCTG
AAAACACAGGGTATCTATCGGACTGTCAAGCTAACGGCGATTAAGAAGATTGTCCCTGTCCAGTCTTGGAATGTTTTTGA
CTGGCTGTCAACTTGGCGGAGGCAGGCCTTGGTCTATGTCAAAACCAATTTTCCGGCTCCCATGAGTCACTACATGACAG
GGCTTTTGTTTGGGGAGCTGGATAGTGATTTTGACCAGATGAGTGACCTCTATTCCAGTCTAGGAATCATTCATCTCTTT
GCCCTGTCTGGTATGCAGGTGGGCTTTTTCATCGACAAGTTTCGTTGGATTTTGTTGCGTCTGGGCTTGACCAAGGAAAC
AGTGGATAAGTTACAAATTCCCTTTTCCCTTGTCTATGCTGGTTTGACAGGCTTTTCTGTGTCGGTGGTGCGGTCCTTGG
TCCAAAAAATTCTGGGTAATCTAGGCTTGCGGAAGTTGGATAATTTTGCGGTGACGGTCTTTATCTGTCTGTTGATACTG
CCCCGATTTTTACTGACAGCAGGAGGAGTGCTGACTTTTACTTATGCTTTCTTGCTGACGGTCTTTGATTTTGAGGATTT
GGGGCAGGTCAAAAAGGCTGCGGTGGAGAGCCTCAGTATTTCACTGGGAATTTTGCCGGTGCTTATGACCTATTTCTATG
CCTTTCAGCCTCTATCTATCCTCTTGACCTTTGTCTTTTCCTTTGTCTTTGATGTCCTACTCTTGCCAGGTTTGTCAGTC
ATTTTTCTCCTGTCGCCAGTTGTCAAGATGACTTGGATCAACGGATTTTTCGTCTTTATGGAGAAAATCATTGTCTGGGT
GGCTGATTTGGGATTGCGGCCTTGGATACTGGGCAAGCCGTCTGAGCTGGTCCTCTTGCTTTTGCTGGTCAGCCTCTTCT
TGCTCTACGATTTCCACAGGAGAAAGAAATGGCTTCTAGGACTGAGCTTGGTCCTCGCTCTGCTATTTTTCATCACCAAA
CACCCGCTGGAAAATGAGGTGACGGTGCTGGACATCGGGCAGGGGGACAGCATCTTTTTGCGGGATATGCGGGGGCGGAC
GGTTCTGATTGATGTAGGCGGACGAGTCGATTTCGCGGCCAAGGAAGCGTGGCAGGAGCGGTCTCGGCAGGCAAATGCAG
AGCGGACTTTGATTCCCTATCTGCATAGTCGGGGTGTGGATAGGATTGATAGTTTAGTCCTGACCCACACCGACACAGAC
CATGTGGGGGATGTGCTGGAAGTGGCGAAGCAGGTCCAGATTGGTCGGATTGTCGTGTCGCCGGGAAGTCTGACGGTGCC
TGACTTTGTAGCGACCTTGAAAAAAATCAATGTTCCTGTCCATGTGGTAAAAGTGGGCGACCGCCTACCAATTTTTGACT
CCTATCTGGAGGTCCTCTATCCAGACGGGACAGGCGACGGTGGCAATAATGACTCCATTGTCCTTTACGGTCGCTTGTTG
GAAACTAACTTTCTCTTTACAGGAGACCTGGAGCAAGGGGAGTTGGACTTGATAGAAACCTATCCCAACCTGCCTGTCGA
TGTCCTCAAAGCCGGTCACCATGGCTCCAAAGGCTCTTCTTATCCTGAATTTTTAGACCATATCGGTGCCAAGATTGCCT
TGGTATCTGCTGGAGAAAACAACCGCTACAAGCATCCTCACCAAGAAACCTTGGAACGATTTGACAGCCGGAATATCCAA
GTCTATCGCACAGACCAGCAAGGAGCCATTCGCTTCCGAGGTTGGAAGGAGTGGAAGATTGAGACGGTGAGGAGGTAA

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (493-698)

• Domain of unknown function (DUF4131) (DUF4131) (30-175)

• Competence protein (Competence) (215-461)

3D structure

• AlphaFold DB: A0A0H3MWC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	53.774	99.597	0.536
comEC/celB	Streptococcus mitis NCTC 12261	52.917	98.926	0.523
comEC/celB	Streptococcus pneumoniae TIGR4	51.973	98.658	0.513
comEC/celB	Streptococcus pneumoniae Rx1	51.701	98.658	0.51
comEC/celB	Streptococcus pneumoniae D39	51.701	98.658	0.51
comEC/celB	Streptococcus pneumoniae R6	51.701	98.658	0.51
comEC	Lactococcus lactis subsp. cremoris KW2	49.399	100	0.497