Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpP   Type   Regulator
Locus tag   EXW49_RS25255 Genome accession   NZ_CP036023
Coordinates   4904927..4905508 (+) Length   193 a.a.
NCBI ID   WP_001049163.1    Uniprot ID   A0A366GQ86
Organism   Bacillus mycoides strain BPN52/2     
Function   degradation of ComK; degradation of DegU (predicted from homology)   
Competence regulation

Genomic Context

Location: 4899927..4910508
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EXW49_RS25220 (EXW49_25700) - 4900910..4901116 (+) 207 WP_000216167.1 DUF1657 domain-containing protein -
  EXW49_RS25225 (EXW49_25705) - 4901223..4901711 (+) 489 WP_002143725.1 YhcN/YlaJ family sporulation lipoprotein -
  EXW49_RS25230 (EXW49_25710) spoVAC 4901740..4902216 (+) 477 WP_002034730.1 stage V sporulation protein AC -
  EXW49_RS25235 (EXW49_25715) spoVAD 4902217..4903233 (+) 1017 WP_000938981.1 stage V sporulation protein AD -
  EXW49_RS25240 (EXW49_25720) spoVAE 4903230..4903580 (+) 351 WP_000575919.1 stage V sporulation protein AE -
  EXW49_RS25245 (EXW49_25725) - 4903590..4903796 (+) 207 WP_215588610.1 DUF1657 domain-containing protein -
  EXW49_RS25250 (EXW49_25730) - 4903817..4904686 (+) 870 WP_002016080.1 DUF421 domain-containing protein -
  EXW49_RS25255 (EXW49_25735) clpP 4904927..4905508 (+) 582 WP_001049163.1 ATP-dependent Clp endopeptidase proteolytic subunit ClpP Regulator
  EXW49_RS25260 (EXW49_25740) - 4905957..4906205 (-) 249 WP_002016081.1 HPr family phosphocarrier protein -
  EXW49_RS25265 (EXW49_25745) whiA 4906229..4907179 (-) 951 WP_002016082.1 DNA-binding protein WhiA -
  EXW49_RS25270 (EXW49_25750) - 4907268..4908221 (-) 954 WP_002016083.1 YvcK family protein -
  EXW49_RS25275 (EXW49_25755) rapZ 4908225..4909106 (-) 882 WP_002016084.1 RNase adapter RapZ -
  EXW49_RS25280 (EXW49_25760) - 4909127..4909585 (-) 459 WP_002124062.1 8-oxo-dGTP diphosphatase -

Sequence

Protein


Download         Length: 193 a.a.        Molecular weight: 21447.68 Da        Isoelectric Point: 5.0423

>NTDB_id=346001 EXW49_RS25255 WP_001049163.1 4904927..4905508(+) (clpP) [Bacillus mycoides strain BPN52/2]
MNLIPTVIEQTNRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLESQDPEKDIHIYINSPGGSITAGMAIYDT
MQFIKPQVSTICIGMAASMGAFLLAAGEKGKRYALPNSEVMIHQPLGGAQGQATEIEIAAKRILFLREKLNQILADRTGQ
PLEVLQRDTDRDNFMTAERALEYGLIDKIFTNR

Nucleotide


Download         Length: 582 bp        

>NTDB_id=346001 EXW49_RS25255 WP_001049163.1 4904927..4905508(+) (clpP) [Bacillus mycoides strain BPN52/2]
ATGAATTTAATTCCTACAGTAATTGAACAAACAAATCGTGGAGAACGCGCTTACGATATTTACTCTCGACTATTAAAAGA
TCGCATCATTATGCTTGGTAGCGCAATTGATGACAACGTAGCAAACTCAATCGTTTCCCAGCTTTTATTCTTGGAATCTC
AAGATCCAGAAAAAGATATTCACATTTACATCAACAGCCCTGGTGGTTCTATCACAGCTGGTATGGCAATTTACGATACA
ATGCAGTTTATTAAACCACAAGTATCAACAATCTGTATCGGTATGGCTGCATCTATGGGTGCATTCTTACTTGCAGCAGG
TGAAAAAGGAAAACGTTACGCACTTCCAAACAGTGAAGTTATGATTCACCAACCACTTGGCGGAGCACAAGGTCAAGCGA
CTGAAATCGAAATCGCTGCAAAACGTATCCTATTCTTACGTGAAAAATTAAACCAAATTCTTGCTGACCGCACAGGTCAA
CCACTTGAAGTTCTACAACGCGACACAGACCGCGACAACTTCATGACAGCAGAAAGAGCTCTAGAATACGGCTTAATCGA
TAAGATCTTTACAAATCGTTAA

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(13-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A366GQ86

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Bacillus subtilis subsp. subtilis str. 168

90.104

99.482

0.896
  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

67.021

97.409

0.653
  clpP Streptococcus thermophilus LMG 18311

60.417

99.482

0.601
  clpP Streptococcus thermophilus LMD-9

60.417

99.482

0.601
  clpP Lactococcus lactis subsp. cremoris KW2

58.854

99.482

0.585
  clpP Streptococcus pneumoniae D39

57.292

99.482

0.57
  clpP Streptococcus pneumoniae Rx1

57.292

99.482

0.57
  clpP Streptococcus pneumoniae R6

57.292

99.482

0.57
  clpP Streptococcus pneumoniae TIGR4

57.292

99.482

0.57
  clpP Lactococcus lactis subsp. lactis strain DGCC12653

56.771

99.482

0.565
  clpP Streptococcus pyogenes JRS4

55.729

99.482

0.554
  clpP Streptococcus pyogenes MGAS315

55.729

99.482

0.554
  clpP Streptococcus mutans UA159

55.44

100

0.554

Multiple sequence alignment