Detailed information NTG0345237

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: GFB63_RS06045
• Genome accession: NZ_CP045596
• Coordinates: 1172836..1173405 (+)
• Length: 189 a.a.
• NCBI ID: WP_265578821.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain TK-P3A
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1167836..1178405

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GFB63_RS06015 (GFB63_06185)	-	1167978..1168517 (+)	540	WP_372585740.1	tRNA (cytidine(34)-2'-O)-methyltransferase	-
GFB63_RS06020 (GFB63_06190)	-	1168828..1169385 (+)	558	WP_111679227.1	ECF transporter S component	-
GFB63_RS06025 (GFB63_06195)	-	1169388..1170038 (+)	651	WP_193838187.1	phosphatase PAP2 family protein	-
GFB63_RS06030 (GFB63_06200)	comR	1170233..1171132 (+)	900	WP_111679231.1	helix-turn-helix domain-containing protein	Regulator
GFB63_RS10925	-	1171370..1171666 (+)	297	Protein_1151	cysteine peptidase family C39 domain-containing protein	-
GFB63_RS10930	comA	1171832..1172227 (+)	396	WP_252989162.1	ABC transporter transmembrane domain-containing protein	Regulator
GFB63_RS10935 (GFB63_06210)	comA	1172311..1172781 (+)	471	WP_265578820.1	ABC transporter transmembrane domain-containing protein	Regulator
GFB63_RS06045 (GFB63_06215)	comA	1172836..1173405 (+)	570	WP_265578821.1	ATP-binding cassette domain-containing protein	Regulator
GFB63_RS06050 (GFB63_06220)	-	1173512..1173778 (+)	267	WP_228024372.1	DUF805 domain-containing protein	-
GFB63_RS10605	-	1173989..1174468 (-)	480	WP_228024373.1	DUF4153 domain-containing protein	-
GFB63_RS10610	-	1174910..1175281 (-)	372	WP_224107488.1	hypothetical protein	-
GFB63_RS06060 (GFB63_06240)	-	1175686..1176201 (+)	516	WP_024704185.1	AmiS/UreI family transporter	-
GFB63_RS06065 (GFB63_06245)	-	1176226..1176528 (+)	303	WP_100273340.1	urease subunit gamma	-
GFB63_RS06070 (GFB63_06250)	-	1176540..1176851 (+)	312	WP_100273339.1	urease subunit beta	-

Sequence

Protein

• Length: 189 a.a.
• Molecular weight: 20652.55 Da
• Isoelectric Point: 6.4865

>NTDB_id=345237 GFB63_RS06045 WP_265578821.1 1172836..1173405(+) (comA) [Streptococcus thermophilus strain TK-P3A]
MGQSSSGKTTLAKISSGYYTKSSGHVSLDKASISQAELRQLVTYVPQKTYVFTGTILENLLLGLEGEVDEHLILKVCEQA
DILADIQKMPLGFQTQVSEDGGLSGGQKQRLAIARALLSNQPILIFDEATSGLDRETESRVMANLSELTRTMIFIAHRSS
VYQHVSRVVTMANGKLEAASPNFNPFQFI

Nucleotide

• Length: 570 bp

>NTDB_id=345237 GFB63_RS06045 WP_265578821.1 1172836..1173405(+) (comA) [Streptococcus thermophilus strain TK-P3A]
ATGGGTCAGAGTAGTTCTGGGAAAACGACTTTAGCGAAGATTTCGTCAGGTTATTACACAAAATCTAGTGGTCATGTAAG
CCTAGACAAAGCTTCTATTAGCCAAGCGGAGTTGCGCCAGTTGGTGACCTATGTTCCACAAAAGACCTATGTCTTTACGG
GAACAATATTAGAAAATCTATTGTTAGGCCTTGAAGGAGAAGTTGATGAGCATCTTATTCTGAAAGTCTGTGAACAAGCC
GATATTTTGGCTGATATTCAAAAGATGCCCCTAGGTTTTCAGACCCAAGTATCTGAAGATGGAGGTCTGTCTGGCGGTCA
AAAACAAAGATTAGCTATAGCAAGGGCTCTCTTGTCCAATCAACCAATCTTGATTTTTGATGAAGCTACAAGTGGTCTGG
ACAGGGAAACTGAAAGTAGAGTAATGGCCAATCTTTCTGAACTGACACGAACAATGATTTTCATTGCTCACCGTAGCAGT
GTCTACCAACATGTCAGTCGTGTAGTGACTATGGCAAATGGGAAGCTTGAAGCAGCTAGTCCCAACTTCAATCCATTCCA
GTTCATTTAA

Domains

Predicted by InterProScan.

• ABC transporter (ABC_tran) (1-131)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis SK321	50	95.238	0.476
comA	Streptococcus pneumoniae Rx1	49.444	95.238	0.471
comA	Streptococcus pneumoniae D39	49.444	95.238	0.471
comA	Streptococcus pneumoniae R6	49.444	95.238	0.471
comA	Streptococcus mitis NCTC 12261	48.889	95.238	0.466
comA	Streptococcus pneumoniae TIGR4	48.889	95.238	0.466
comA	Streptococcus gordonii str. Challis substr. CH1	48.333	95.238	0.46
comA/nlmT	Streptococcus mutans UA159	46.111	95.238	0.439