Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA   Type   Machinery gene
Locus tag   SZO_RS00655 Genome accession   NC_012470
Coordinates   116802..117740 (+) Length   312 a.a.
NCBI ID   WP_012677233.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 111802..122740
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SZO_RS00635 (SZO_00950) - 111953..112999 (+) 1047 WP_046154724.1 acyltransferase family protein -
  SZO_RS00640 (SZO_00960) - 113060..113425 (+) 366 WP_012677230.1 DUF1033 family protein -
  SZO_RS00645 (SZO_00970) - 113970..115973 (+) 2004 WP_012677231.1 DUF1430 domain-containing protein -
  SZO_RS00650 (SZO_00980) - 115975..116622 (+) 648 WP_012677232.1 ATP-binding cassette domain-containing protein -
  SZO_RS00655 (SZO_00990) comGA/cglA 116802..117740 (+) 939 WP_012677233.1 competence type IV pilus ATPase ComGA Machinery gene
  SZO_RS00660 (SZO_01000) comYB 117673..118707 (+) 1035 WP_228274883.1 competence type IV pilus assembly protein ComGB Machinery gene
  SZO_RS00665 (SZO_01010) comGC/cglC 118708..119031 (+) 324 WP_012677235.1 competence type IV pilus major pilin ComGC Machinery gene
  SZO_RS00670 (SZO_01020) comGD 119009..119434 (+) 426 WP_012514783.1 competence type IV pilus minor pilin ComGD -
  SZO_RS00675 (SZO_01030) comGE 119439..119681 (+) 243 WP_012677236.1 competence type IV pilus minor pilin ComGE -
  SZO_RS00680 (SZO_01040) comYF 119668..120102 (+) 435 WP_012677237.1 competence type IV pilus minor pilin ComGF Machinery gene
  SZO_RS00685 (SZO_01050) comGG 120080..120442 (+) 363 WP_012677238.1 competence type IV pilus minor pilin ComGG -
  SZO_RS00690 (SZO_01060) comYH 120504..121457 (+) 954 WP_012677239.1 class I SAM-dependent methyltransferase Machinery gene
  SZO_RS00695 (SZO_01070) - 121517..122716 (+) 1200 WP_012677240.1 acetate kinase -

Sequence

Protein


Download         Length: 312 a.a.        Molecular weight: 35248.56 Da        Isoelectric Point: 7.0749

>NTDB_id=33439 SZO_RS00655 WP_012677233.1 116802..117740(+) (comGA/cglA) [Streptococcus equi subsp. zooepidemicus]
MIQELAKRLIRQAEELQAQDIYILPRGTGYELLMRVGDDRRLIDVCESDRMANLISHFKFVAGMNVGEKRRCQLGACDYD
LDGVKVSLRLSAVGDYQGQESLVIRLLYHCRRQLRYWFDGLERVTSAIGARGLYLFSGPVGSGKTTLMYQLVSDYCKELQ
VISIEDPVEIKNDQLLQLQVNDSIGMTYDNLIKLSLRHRPDVLIIGEIRDTQTARAVIRASLTGAMVFSTVHAKSISGVY
ARLLELGISRAELDNSLAMVAYQRFISGGALIDCAQKEFEHHQASQWNQQIDQLLAEGHLNTKQARLEKIIQ

Nucleotide


Download         Length: 939 bp        

>NTDB_id=33439 SZO_RS00655 WP_012677233.1 116802..117740(+) (comGA/cglA) [Streptococcus equi subsp. zooepidemicus]
ATGATTCAAGAATTAGCCAAGCGGCTTATCAGGCAGGCTGAAGAATTGCAGGCTCAGGATATTTATATACTACCAAGGGG
GACAGGCTATGAGCTTTTGATGAGGGTAGGTGATGACAGGAGGCTAATAGATGTTTGTGAAAGTGATCGGATGGCTAATC
TTATTAGTCACTTTAAGTTCGTTGCAGGAATGAATGTGGGCGAAAAAAGACGCTGCCAGCTCGGTGCTTGTGACTACGAC
CTTGATGGCGTTAAGGTGTCTCTACGATTATCAGCTGTGGGTGATTATCAGGGACAGGAGAGCTTGGTTATTCGTCTCTT
GTATCATTGTCGACGCCAGCTCAGGTATTGGTTTGATGGTTTAGAGCGAGTCACATCAGCTATTGGAGCTAGAGGCCTTT
ACCTCTTTTCTGGACCAGTCGGATCAGGTAAGACAACCCTGATGTATCAGCTAGTCTCTGACTATTGCAAGGAGCTTCAG
GTGATCAGTATTGAGGATCCTGTGGAAATAAAAAATGACCAGCTCCTGCAATTACAGGTTAACGACAGCATTGGCATGAC
ATACGATAATCTGATTAAGCTCTCCTTGCGTCATCGTCCAGATGTGTTGATTATCGGAGAAATTAGAGATACACAGACTG
CTAGAGCGGTTATTAGGGCTAGCCTAACAGGAGCAATGGTCTTTTCAACCGTCCATGCAAAGAGTATTTCAGGCGTTTAC
GCTAGGCTGCTAGAATTAGGCATTTCTAGGGCAGAATTGGATAATAGTCTAGCAATGGTTGCTTACCAGCGATTTATTAG
TGGAGGTGCTTTAATTGATTGTGCGCAAAAGGAATTTGAACATCATCAAGCCAGCCAGTGGAATCAGCAGATTGATCAGC
TTCTTGCAGAGGGACATCTCAATACCAAGCAGGCAAGGCTTGAAAAAATTATCCAGTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(10-264)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

68.065

99.359

0.676
  comYA Streptococcus mutans UA159

63.023

99.679

0.628
  comYA Streptococcus mutans UA140

63.023

99.679

0.628
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

61.613

99.359

0.612
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

61.29

99.359

0.609
  comGA/cglA/cilD Streptococcus pneumoniae D39

61.29

99.359

0.609
  comGA/cglA/cilD Streptococcus pneumoniae R6

61.29

99.359

0.609
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

61.29

99.359

0.609
  comYA Streptococcus gordonii str. Challis substr. CH1

60.968

99.359

0.606
  comGA Lactococcus lactis subsp. cremoris KW2

52.733

99.679

0.526
  comGA Latilactobacillus sakei subsp. sakei 23K

40.273

93.91

0.378

Multiple sequence alignment