Detailed information NTG0033179

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: SPJ_RS09890
• Genome accession: NC_012466
• Coordinates: 1863813..1864823 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990611.1
• Uniprot ID: A0A064BY25
• Organism: Streptococcus pneumoniae JJA
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1858813..1869823

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPJ_RS09865 (SPJ_1988)	-	1860163..1860456 (-)	294	WP_000977366.1	hypothetical protein	-
SPJ_RS09870 (SPJ_1989)	-	1860614..1861066 (+)	453	WP_000079148.1	universal stress protein	-
SPJ_RS09875 (SPJ_1990)	-	1861101..1862489 (-)	1389	WP_000453139.1	Cof-type HAD-IIB family hydrolase	-
SPJ_RS09880 (SPJ_1991)	-	1862555..1863517 (+)	963	WP_001124778.1	asparaginase	-
SPJ_RS09885 (SPJ_1992)	-	1863546..1863749 (-)	204	WP_001092045.1	hypothetical protein	-
SPJ_RS09890 (SPJ_1993)	ccpA	1863813..1864823 (-)	1011	WP_000990611.1	catabolite control protein A	Regulator
SPJ_RS09895 (SPJ_1994)	-	1865247..1865846 (-)	600	WP_000866698.1	response regulator transcription factor	-
SPJ_RS09900 (SPJ_1995)	-	1865847..1866944 (-)	1098	WP_000893509.1	sensor histidine kinase	-
SPJ_RS09905 (SPJ_1996)	-	1866944..1867681 (-)	738	WP_000832835.1	ABC transporter permease	-
SPJ_RS09910 (SPJ_1997)	-	1867683..1868567 (-)	885	WP_001055976.1	ABC transporter ATP-binding protein	-
SPJ_RS09915 (SPJ_1998)	-	1868554..1868748 (-)	195	WP_000820189.1	hypothetical protein	-
SPJ_RS13465	-	1868745..1868951 (-)	207	Protein_1881	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37101.07 Da
• Isoelectric Point: 5.3212

>NTDB_id=33179 SPJ_RS09890 WP_000990611.1 1863813..1864823(-) (ccpA) [Streptococcus pneumoniae JJA]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLVKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=33179 SPJ_RS09890 WP_000990611.1 1863813..1864823(-) (ccpA) [Streptococcus pneumoniae JJA]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGTTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGTTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A064BY25

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.405	100	0.994
ccpA	Streptococcus gordonii str. Challis substr. CH1	86.826	99.405	0.863
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568