Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGH   Type   Machinery gene
Locus tag   FP509_RS01470 Genome accession   NZ_CP041999
Coordinates   233942..234916 (+) Length   324 a.a.
NCBI ID   WP_001008574.1    Uniprot ID   Q8E232
Organism   Streptococcus agalactiae strain GBS11     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 228942..239916
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FP509_RS01425 (FP509_01420) - 229940..230836 (+) 897 WP_001061853.1 sensor histidine kinase -
  FP509_RS01430 (FP509_01425) - 230830..231129 (+) 300 WP_000258211.1 STAS-like domain-containing protein -
  FP509_RS01435 (FP509_01430) - 231239..231439 (+) 201 WP_000076712.1 CsbD family protein -
  FP509_RS01440 (FP509_01435) - 231480..231650 (-) 171 WP_000356856.1 hypothetical protein -
  FP509_RS10940 - 231786..231911 (-) 126 WP_017285425.1 hypothetical protein -
  FP509_RS01445 (FP509_01440) comGC 232135..232404 (+) 270 WP_000962019.1 competence type IV pilus major pilin ComGC Machinery gene
  FP509_RS01450 (FP509_01445) comGD 232379..232792 (+) 414 WP_000244261.1 competence type IV pilus minor pilin ComGD Machinery gene
  FP509_RS01455 (FP509_01450) comGE 232764..233063 (+) 300 WP_000234804.1 competence type IV pilus minor pilin ComGE Machinery gene
  FP509_RS01460 (FP509_01455) comGF 233017..233478 (+) 462 WP_001878820.1 competence type IV pilus minor pilin ComGF Machinery gene
  FP509_RS01465 (FP509_01460) comGG 233456..233827 (+) 372 WP_000601104.1 competence type IV pilus minor pilin ComGG Machinery gene
  FP509_RS01470 (FP509_01465) comGH 233942..234916 (+) 975 WP_001008574.1 class I SAM-dependent methyltransferase Machinery gene
  FP509_RS01475 (FP509_01470) - 234948..236141 (+) 1194 WP_000047534.1 acetate kinase -
  FP509_RS01480 (FP509_01475) - 236293..236499 (+) 207 WP_000798241.1 helix-turn-helix transcriptional regulator -
  FP509_RS01485 (FP509_01480) - 236558..236695 (+) 138 WP_001865900.1 hypothetical protein -
  FP509_RS01490 (FP509_01485) - 236736..237191 (+) 456 WP_000905673.1 hypothetical protein -
  FP509_RS01495 (FP509_01490) - 237260..237925 (+) 666 WP_000008113.1 CPBP family intramembrane glutamic endopeptidase -
  FP509_RS01500 (FP509_01495) proC 237946..238716 (-) 771 WP_001865901.1 pyrroline-5-carboxylate reductase -
  FP509_RS01505 (FP509_01500) pepA 238786..239853 (-) 1068 WP_001281323.1 glutamyl aminopeptidase -

Sequence

Protein


Download         Length: 324 a.a.        Molecular weight: 37046.02 Da        Isoelectric Point: 4.5224

>NTDB_id=329477 FP509_RS01470 WP_001008574.1 233942..234916(+) (comGH) [Streptococcus agalactiae strain GBS11]
MNFEKIETAYELILENIQTIENQLKTHIYDALIEQNSYYLGSSCDLDMVVVNNQKLRQLDLSQEEWRRTFQFIFIKSAQT
EQLQANHQFTPDSIGFILLFLLEELTSQETVDVLEIGSGTGNLAQTLLNNSSKELNYMGIEVDDLLIDLSASIAEIIGSS
AQFIQEDAVRPQILKESDVIISDLPVGYYPNDGIAKRYAVSSSKEHTYAHHLLMEQSLKYLKKDGIAIFLAPENLLTSPQ
SDLLKEWLKGYADVIAVLTLPETIFGSRQNAKSIFVLKKQAEQKPETFVYPLTDLQNRENMANFIENFQKWSRENSHYSK
NMIK

Nucleotide


Download         Length: 975 bp        

>NTDB_id=329477 FP509_RS01470 WP_001008574.1 233942..234916(+) (comGH) [Streptococcus agalactiae strain GBS11]
ATGAATTTTGAAAAAATTGAGACAGCCTATGAGCTGATTTTAGAAAATATCCAAACGATTGAGAACCAATTAAAAACTCA
TATTTATGATGCCTTAATTGAACAGAACTCTTATTACCTTGGTTCAAGTTGTGATTTAGATATGGTTGTGGTGAATAACC
AAAAATTACGTCAACTTGACTTAAGTCAAGAAGAATGGCGTCGCACTTTCCAGTTCATTTTTATCAAATCTGCGCAAACA
GAGCAATTACAAGCTAATCATCAGTTTACGCCAGATAGTATTGGTTTTATCTTGTTATTTCTTTTGGAAGAATTAACGAG
TCAAGAGACAGTGGATGTCTTGGAAATTGGAAGTGGAACTGGGAATTTAGCTCAGACTCTCCTCAATAACAGCTCGAAAG
AGTTAAATTATATGGGCATTGAAGTTGATGATCTTTTGATTGATCTATCAGCAAGCATTGCTGAAATTATAGGTTCTAGT
GCCCAATTTATCCAAGAGGATGCTGTTAGACCACAAATTTTGAAAGAAAGCGATGTAATCATTAGTGATTTACCAGTTGG
CTATTATCCTAATGATGGTATTGCTAAACGATATGCTGTATCAAGTTCTAAAGAGCACACCTATGCTCACCATCTATTGA
TGGAGCAATCTCTTAAATATTTGAAAAAAGATGGAATCGCTATATTTTTAGCACCCGAAAACCTTTTAACAAGTCCACAA
AGTGATTTGCTGAAGGAGTGGTTAAAAGGATATGCAGATGTCATTGCCGTTTTAACTCTACCAGAAACTATTTTTGGAAG
TCGTCAAAATGCGAAATCTATATTTGTTCTCAAGAAGCAAGCAGAACAAAAACCAGAAACCTTTGTATATCCGCTGACAG
ATTTGCAAAATCGTGAGAATATGGCAAACTTCATTGAAAATTTTCAAAAATGGAGCAGAGAAAATAGTCATTACTCAAAA
AATATGATAAAATAG

Domains

Predicted by InterProScan.

N-6 DNA Methylase (N6_Mtase)

(70-303)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q8E232

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGH Streptococcus mutans UA159

67.302

97.222

0.654
  comGH Streptococcus mutans UA140

67.302

97.222

0.654