Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   ES300_RS05365 Genome accession   NZ_CP038251
Coordinates   1080722..1081186 (-) Length   154 a.a.
NCBI ID   WP_001135768.1    Uniprot ID   A4L7L7
Organism   Streptococcus pneumoniae strain TVO_1901944     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1075722..1086186
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ES300_RS05345 (ES300_05630) - 1076673..1077641 (-) 969 WP_000105360.1 thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha -
  ES300_RS05350 (ES300_05635) pdrM 1077795..1079156 (-) 1362 WP_000278534.1 sodium-coupled multidrug efflux MATE transporter PdrM -
  ES300_RS05355 (ES300_05640) - 1079167..1079427 (-) 261 WP_001105925.1 hypothetical protein -
  ES300_RS05360 (ES300_05645) - 1079441..1080709 (-) 1269 WP_000924489.1 dihydroorotase -
  ES300_RS05365 (ES300_05650) mutX 1080722..1081186 (-) 465 WP_001135768.1 8-oxo-dGTP diphosphatase Machinery gene
  ES300_RS05370 (ES300_05655) - 1081196..1081849 (-) 654 WP_000401326.1 uracil-DNA glycosylase -
  ES300_RS05375 (ES300_05660) - 1081987..1082634 (-) 648 WP_078152041.1 hypothetical protein -
  ES300_RS05380 (ES300_05665) - 1082648..1083361 (-) 714 WP_000499437.1 YjjG family noncanonical pyrimidine nucleotidase -
  ES300_RS05385 (ES300_05670) dhaM 1083820..1084200 (-) 381 WP_000443785.1 dihydroxyacetone kinase phosphoryl donor subunit DhaM -
  ES300_RS10780 - 1084200..1084274 (-) 75 Protein_1085 dihydroxyacetone kinase subunit L -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 17812.16 Da        Isoelectric Point: 4.2287

>NTDB_id=310104 ES300_RS05365 WP_001135768.1 1080722..1081186(-) (mutX) [Streptococcus pneumoniae strain TVO_1901944]
MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGETPQECAAREILEETGLKAKPVLKGVITFPEFTPDLD
WYTYVFKVTEFEGDLIDCNEGTLEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE

Nucleotide


Download         Length: 465 bp        

>NTDB_id=310104 ES300_RS05365 WP_001135768.1 1080722..1081186(-) (mutX) [Streptococcus pneumoniae strain TVO_1901944]
ATGCCTCAGTTAGCGACGATTTGCTACATTGATAATGGGAAAGAACTGCTCATGCTCCATCGTAATAAGAAACCCAATGA
TGTCCATGAAGGGAAATGGATTGGTGTGGGTGGTAAGCTAGAGAGAGGAGAGACGCCCCAGGAATGCGCGGCGCGTGAAA
TCCTTGAAGAAACAGGGCTCAAAGCCAAGCCAGTTCTAAAAGGTGTCATCACTTTTCCTGAATTTACACCAGATTTAGAC
TGGTACACCTATGTTTTTAAGGTGACGGAGTTTGAGGGCGACTTGATTGACTGCAATGAGGGGACGCTAGAATGGGTTCC
CTATGATGAGGTTTTGAGCAAGCCGACTTGGGAAGGTGACCACACCTTTGTTGAGTGGCTTTTAGAGGATAAACCCTTCT
TTTCAGCCAAGTTTGTTTATGATGGGGATAAATTGTTGGATACCCAAGTTGATTTCTATGAATAA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-127)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A4L7L7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

98.701

100

0.987

Multiple sequence alignment