Detailed information NTG0306428

Bioinformatically predicted

Overview

• Name: pilS
• Type: Regulator
• Locus tag: DMO12_RS01420
• Genome accession: NZ_CP031380
• Coordinates: 291562..293130 (-)
• Length: 522 a.a.
• NCBI ID: WP_001160337.1
• Uniprot ID: B4YSY0
• Organism: Acinetobacter baumannii ACICU
• Function: regulation of type IV pilus assembly (predicted from homology) Competence regulation

Genomic Context

Location: 286562..298130

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DMO12_RS01405 (DMO12_00825)	gpmI	287365..288912 (+)	1548	WP_000128749.1	2,3-bisphosphoglycerate-independent phosphoglycerate mutase	-
DMO12_RS01410 (DMO12_00828)	-	288928..290112 (+)	1185	WP_000939109.1	S41 family peptidase	-
DMO12_RS01415 (DMO12_00831)	pilR	290116..291537 (-)	1422	WP_000840548.1	sigma-54 dependent transcriptional regulator	Regulator
DMO12_RS01420 (DMO12_00834)	pilS	291562..293130 (-)	1569	WP_001160337.1	PAS domain-containing sensor histidine kinase	Regulator
DMO12_RS01425 (DMO12_00837)	-	293141..293776 (-)	636	WP_000633799.1	response regulator	-
DMO12_RS01430 (DMO12_00840)	pbpG	293989..295035 (+)	1047	WP_003384760.1	D-alanyl-D-alanine endopeptidase PBP7/8	-
DMO12_RS01435 (DMO12_00843)	thrC	295142..296281 (-)	1140	WP_000063593.1	threonine synthase	-
DMO12_RS01440 (DMO12_00846)	-	296337..297638 (-)	1302	WP_000805827.1	homoserine dehydrogenase	-

Sequence

Protein

• Length: 522 a.a.
• Molecular weight: 59227.74 Da
• Isoelectric Point: 6.4995

>NTDB_id=306428 DMO12_RS01420 WP_001160337.1 291562..293130(-) (pilS) [Acinetobacter baumannii ACICU]
MQFPLNSSLSHTIFRLGTWYGLYRLIIAVSLNIILVLTDAQTDNSLQQPALYSYTLLGYSLLSLVQLLCFKFIATQATRQ
LILFFIVDIICLSLLTFSVGEPNLQLSLLYVIAIFTSAILLSARMSLLITLLAVIAVIYQRFVGSLFDYNNLNTIGNSAL
LAFLFFVVHGIGQIAVQRFKLLEALTFHQSIELYQLQNINRYILEQIEEGYLVLDENYDIVVSNPAACSLLGIPPQFANE
KYPLAKWHTDLFEILKFGDLKEGDRFIFESRLSAYSINIKVQHLLVPQQTLTLLILQDAQQINQQAQQLKLAALGQLSAS
IAHEIRNPLAAIVQANELLKDSDPEQQNTLRHIIGKQTKRIDSIVQDTLGLARSERTHPIQIDVKHFIDTLLEEDLFDVK
HSIQLKISDSSLKFLFDEKQLRQVMINLVRNALRHNAPDSLYITINIHSQTNKIYIDVIDYGEGVSKRDISQLFKPFFST
EINGTGLGLYLSHSFCEANHAKLTYVEQKQGACFRIECPIIY

Nucleotide

• Length: 1569 bp

>NTDB_id=306428 DMO12_RS01420 WP_001160337.1 291562..293130(-) (pilS) [Acinetobacter baumannii ACICU]
ATGCAATTTCCCTTAAATTCATCCTTGTCCCATACGATTTTTCGTTTGGGCACTTGGTATGGCTTATACCGTCTTATTAT
TGCGGTTAGCCTGAATATTATTTTAGTTTTAACCGATGCGCAAACTGATAACAGTTTGCAGCAACCTGCCTTATATTCCT
ACACACTACTCGGCTATTCGCTCTTAAGTCTTGTTCAGCTGTTATGCTTTAAATTTATTGCCACTCAAGCCACACGACAG
CTTATTTTATTTTTTATTGTTGATATTATTTGTTTGAGTTTACTGACTTTTTCTGTGGGTGAACCAAATTTACAACTCAG
CTTACTCTATGTAATTGCTATCTTTACCTCGGCGATTTTGCTCAGCGCAAGAATGTCTTTGCTGATTACATTGCTTGCGG
TTATTGCTGTTATTTACCAACGATTTGTAGGTAGCCTATTTGACTATAACAATCTAAATACTATTGGTAATAGCGCTCTC
TTAGCTTTCTTATTTTTTGTGGTTCACGGAATTGGCCAAATTGCAGTGCAGCGCTTTAAATTACTTGAAGCACTCACCTT
TCACCAGTCAATTGAACTTTATCAACTCCAAAATATTAACCGTTATATCTTAGAACAAATTGAAGAAGGCTATTTAGTTT
TGGATGAGAATTACGACATCGTTGTCAGTAATCCTGCGGCCTGTTCACTCTTGGGTATTCCCCCTCAATTTGCCAATGAA
AAATATCCTTTAGCAAAGTGGCATACCGATTTATTTGAAATTTTAAAGTTTGGCGACTTAAAAGAAGGTGACCGATTCAT
TTTTGAGTCTCGGCTATCGGCATACTCCATCAACATTAAAGTGCAACACCTTTTGGTCCCACAACAAACGTTAACTCTGC
TCATTTTACAAGATGCCCAACAAATTAATCAGCAAGCCCAGCAGCTTAAGCTTGCTGCGCTAGGGCAACTCTCAGCAAGT
ATTGCACATGAGATCCGCAATCCTCTCGCTGCAATCGTACAAGCAAATGAGTTACTGAAAGATAGCGATCCAGAACAACA
AAATACTTTGCGTCATATAATTGGCAAACAAACCAAACGCATTGATAGTATTGTTCAAGATACTTTAGGGCTTGCTCGTA
GCGAAAGAACACATCCTATCCAGATCGATGTAAAACACTTCATAGATACATTGCTCGAAGAAGATTTATTTGACGTTAAA
CATTCAATTCAACTTAAAATTTCGGATAGTTCTTTAAAATTTTTATTTGATGAAAAACAATTAAGACAAGTCATGATCAA
TCTGGTGAGAAATGCTTTACGGCATAATGCCCCCGACTCACTGTACATTACGATCAACATTCATTCACAGACAAATAAAA
TTTATATTGATGTGATCGATTACGGTGAAGGTGTTTCAAAACGTGATATATCTCAATTATTTAAACCATTTTTTAGTACC
GAAATTAATGGAACTGGATTAGGATTATATTTGTCTCATAGTTTTTGTGAGGCTAACCATGCAAAGCTCACCTATGTAGA
GCAAAAACAAGGGGCATGCTTCAGAATAGAATGCCCAATAATATATTGA

Domains

Predicted by InterproScan.

• His Kinase A (phospho-acceptor) domain (HisKA) (313-375)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (417-518)

• PAS fold (PAS) (203-250)

3D structure

• AlphaFold DB: B4YSY0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilS	Acinetobacter baumannii strain A118	99.234	100	0.992