Detailed information NTG0305245

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: DWB87_RS13400
• Genome accession: NZ_CP031265
• Coordinates: 2631263..2632150 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143417.1
• Uniprot ID: A0A641A7I7
• Organism: Staphylococcus aureus strain 13
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2626263..2637150

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DWB87_RS13365 (DWB87_13670)	-	2626282..2626374 (+)	93	WP_010956583.1	hypothetical protein	-
DWB87_RS13370 (DWB87_13675)	-	2626482..2626979 (-)	498	WP_001065268.1	glutathione peroxidase	-
DWB87_RS13375 (DWB87_13680)	-	2626989..2627249 (-)	261	WP_001791974.1	hypothetical protein	-
DWB87_RS13385 (DWB87_13690)	-	2627631..2627744 (-)	114	Protein_2537	hypothetical protein	-
DWB87_RS13390 (DWB87_13695)	-	2628403..2630403 (-)	2001	WP_060552582.1	ABC transporter permease	-
DWB87_RS13395 (DWB87_13700)	-	2630400..2631155 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
DWB87_RS13400 (DWB87_13705)	braS	2631263..2632150 (-)	888	WP_000143417.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
DWB87_RS13405 (DWB87_13710)	braR	2632161..2632826 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
DWB87_RS13410 (DWB87_13715)	-	2632852..2633052 (-)	201	WP_000604727.1	hypothetical protein	-
DWB87_RS13415 (DWB87_13720)	-	2633250..2634674 (+)	1425	WP_000953748.1	alkaline phosphatase	-
DWB87_RS14080 (DWB87_13725)	-	2634734..2634835 (-)	102	WP_000731972.1	SE2200 family small protein	-
DWB87_RS13425 (DWB87_13730)	-	2634957..2635412 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
DWB87_RS13430 (DWB87_13735)	-	2635657..2636418 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34027.28 Da
• Isoelectric Point: 5.8962

>NTDB_id=305245 DWB87_RS13400 WP_000143417.1 2631263..2632150(-) (braS) [Staphylococcus aureus strain 13]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLLIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=305245 DWB87_RS13400 WP_000143417.1 2631263..2632150(-) (braS) [Staphylococcus aureus strain 13]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTACTGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (192-294)

3D structure

• AlphaFold DB: A0A641A7I7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	98.983	100	0.99