Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilQ   Type   Machinery gene
Locus tag   DV446_RS05360 Genome accession   NZ_CP031252
Coordinates   1037746..1039890 (-) Length   714 a.a.
NCBI ID   WP_074896856.1    Uniprot ID   A0A378U0K4
Organism   Neisseria elongata strain M15911     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1032746..1044890
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV446_RS05345 rpsT 1033306..1033569 (-) 264 WP_041961506.1 30S ribosomal protein S20 -
  DV446_RS05350 - 1033849..1034991 (+) 1143 WP_049249695.1 extracellular solute-binding protein -
  DV446_RS05355 - 1035059..1036936 (-) 1878 WP_074896853.1 monovalent cation:proton antiporter-2 (CPA2) family protein -
  DV446_RS05360 pilQ 1037746..1039890 (-) 2145 WP_074896856.1 type IV pilus secretin PilQ Machinery gene
  DV446_RS05365 - 1039910..1040428 (-) 519 WP_049252834.1 pilus assembly protein PilP -
  DV446_RS05370 - 1040447..1041073 (-) 627 WP_049252880.1 type 4a pilus biogenesis protein PilO -
  DV446_RS05375 - 1041075..1041734 (-) 660 WP_074896860.1 PilN domain-containing protein -
  DV446_RS05380 pilM 1041737..1042834 (-) 1098 WP_074897126.1 type IV pilus assembly protein PilM -

Sequence

Protein


Download         Length: 714 a.a.        Molecular weight: 78157.87 Da        Isoelectric Point: 9.6170

>NTDB_id=305019 DV446_RS05360 WP_074896856.1 1037746..1039890(-) (pilQ) [Neisseria elongata strain M15911]
MKKLVDVKIFPILGMALAVQAVFAGDITDINVSTLPNNQKIVKVKFDKDTVLPSNSMVNEPSSRIALDFPATGVTLPQSS
FEYSDSLLNQVAVVKNGNNARVLLGLNRLGHYKAEVKGKEVWIYINEAVSSSHTTPSAQVVNSKIASSEAAAVTVDFRKS
GRSNGIVEIMTRKYQGKPDIKHNNGSLIITFKNYPLPVQAQRNLDVSDFSTPVRNVVLKRIGNDTQIVIKNQGSWTHDIK
TTNDRFIVEVSQKSSVESSGLPSNQNKSFKGNKVSLDFQDVDVRTVLQILAKESGMNIVASDSVTGKMTLTLKDVPWDQA
LDLVMQARNLDMRKTGNVINVAPREELLAKDKAILTQQREIDELGPLYSRTFQLKYKNVEEFRKILKLDENNSSNTSNNI
NRTILSNRGSALIDPATNTLVITDNTFVLQKFEKLIAELDVPARQVMVEARIVEAEDGFSRQLGVKFGYAGSNGKNSWGS
NWANAGANRNSYVDKQRTLANWSRNPSQDIPALPAWTVDPNVNLPTAAATSSIALVHALSSGALGLELSAQQAQNKLKIV
STPRVLTQDRKEAIIEAGTEVPYQEASSSGATSTSFKKAVLGMTVTPNITPDGQIIMDIKINKDSVNSDCRATEPCINTQ
RLNTNVMVEDGGTLILGGIYQEENSEGVSKVPLLGDIPVVGNLFKSKTRSDKKTELLIFITPRIVDNIGSNLRY

Nucleotide


Download         Length: 2145 bp        

>NTDB_id=305019 DV446_RS05360 WP_074896856.1 1037746..1039890(-) (pilQ) [Neisseria elongata strain M15911]
ATGAAAAAGTTAGTAGATGTTAAAATTTTTCCAATTTTAGGAATGGCATTGGCTGTGCAGGCTGTCTTTGCGGGCGATAT
TACTGATATTAATGTTTCTACATTGCCAAATAATCAGAAGATTGTTAAAGTTAAATTTGATAAAGACACAGTTTTACCAT
CAAATTCGATGGTAAATGAACCTTCTTCTCGTATTGCTTTGGATTTTCCGGCTACTGGAGTGACATTGCCACAATCTTCA
TTTGAGTATTCAGATTCATTATTAAACCAGGTTGCTGTAGTAAAAAATGGAAACAATGCTCGTGTATTGTTGGGTCTAAA
CAGATTAGGACACTATAAAGCAGAGGTTAAAGGTAAAGAAGTTTGGATTTATATTAATGAGGCGGTGTCTTCGAGTCATA
CGACACCAAGTGCTCAAGTTGTAAATAGTAAAATTGCAAGTTCTGAAGCTGCTGCAGTTACGGTTGATTTTAGAAAGTCA
GGAAGATCAAATGGTATTGTTGAGATTATGACTAGAAAATATCAGGGTAAACCTGATATTAAACATAATAATGGTAGTTT
AATAATTACCTTTAAAAATTATCCTCTTCCCGTTCAAGCTCAGCGTAATTTGGATGTGAGTGATTTTAGTACACCCGTGC
GAAATGTTGTCTTAAAAAGAATTGGCAATGATACGCAAATAGTTATTAAGAATCAAGGTTCGTGGACTCATGATATTAAA
ACAACGAATGATAGATTTATTGTTGAAGTAAGTCAGAAATCATCAGTTGAGAGTTCAGGTTTGCCTTCTAATCAGAATAA
ATCATTTAAGGGTAATAAAGTTTCTTTAGACTTTCAAGATGTTGATGTTCGTACAGTGTTGCAAATTCTAGCTAAAGAAT
CAGGTATGAATATTGTAGCTAGCGATAGTGTTACAGGAAAAATGACTTTGACTCTTAAAGATGTCCCTTGGGATCAGGCA
CTAGATTTAGTGATGCAGGCTCGTAATTTAGATATGAGAAAAACAGGTAATGTTATTAATGTAGCGCCTAGAGAAGAGTT
ATTGGCTAAAGATAAAGCGATTCTAACTCAACAGAGAGAAATTGATGAGTTGGGTCCTTTATATTCTAGAACATTCCAAC
TAAAATATAAAAATGTAGAAGAATTTCGTAAAATACTAAAACTTGATGAAAATAATAGTAGCAACACTAGTAATAATATC
AATAGAACGATTTTAAGTAATCGAGGTAGTGCATTAATTGATCCAGCTACTAATACGTTAGTTATTACTGATAATACCTT
TGTACTGCAAAAATTTGAAAAATTAATTGCAGAATTAGATGTTCCCGCACGGCAGGTGATGGTTGAGGCTAGAATTGTGG
AGGCGGAAGACGGCTTCTCACGTCAATTGGGTGTTAAATTCGGATATGCAGGTTCAAATGGTAAAAATAGTTGGGGGAGT
AACTGGGCCAATGCTGGTGCTAACCGTAATAGTTATGTAGATAAGCAAAGAACTCTTGCAAATTGGAGTAGAAATCCATC
CCAAGATATTCCAGCATTGCCAGCATGGACTGTTGACCCTAATGTGAATTTACCTACAGCTGCTGCTACGTCAAGTATTG
CTTTGGTTCATGCGTTATCTTCTGGTGCCCTGGGGTTAGAGCTGTCTGCACAACAGGCGCAGAATAAGTTGAAAATAGTT
TCAACTCCTCGTGTTTTAACGCAGGATCGCAAAGAGGCGATAATTGAAGCGGGTACCGAAGTTCCATATCAAGAAGCTTC
TTCAAGTGGTGCTACATCTACGTCATTTAAGAAAGCAGTATTGGGTATGACTGTAACGCCTAATATCACTCCTGATGGCC
AGATAATTATGGATATTAAGATCAATAAAGATTCAGTAAATTCAGATTGTAGGGCTACCGAACCTTGTATAAATACTCAG
CGTTTAAATACCAATGTTATGGTAGAAGATGGTGGAACGCTAATTTTGGGTGGTATTTATCAAGAGGAAAACTCAGAAGG
CGTAAGTAAAGTTCCATTATTAGGCGATATTCCGGTTGTTGGTAACTTGTTTAAGTCGAAAACTAGATCTGATAAGAAAA
CTGAACTCTTGATTTTCATTACTCCTCGTATTGTTGATAATATTGGTAGCAATTTGAGATATTGA

Domains

Predicted by InterproScan.

Bacterial type II/III secretion system short domain (Secretin_N)

(370-445)

Bacterial type II and III secretion system protein (Secretin)

(551-706)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A378U0K4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilQ Neisseria gonorrhoeae strain FA1090

51.962

100

0.538
  pilQ Neisseria meningitidis MC58

55.575

80.392

0.447
  pilQ Neisseria meningitidis M1080

55.575

80.392

0.447

Multiple sequence alignment