Detailed information NTG0301615

Bioinformatically predicted

Overview

• Name: irvR
• Type: Regulator
• Locus tag: ETT64_RS00645
• Genome accession: NZ_CP035435
• Coordinates: 92979..93746 (-)
• Length: 255 a.a.
• NCBI ID: WP_003058809.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain emm64.3
• Function: regulate expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 87979..98746

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT64_RS00620 (ETT64_00620)	-	88393..89112 (+)	720	WP_136293158.1	metal ABC transporter ATP-binding protein	-
ETT64_RS00625 (ETT64_00625)	-	89105..89920 (+)	816	WP_021340473.1	metal ABC transporter permease	-
ETT64_RS00630 (ETT64_00630)	-	89960..90343 (-)	384	WP_136272095.1	HIT family protein	-
ETT64_RS00635 (ETT64_00635)	-	90507..91652 (-)	1146	WP_032465792.1	site-specific integrase	-
ETT64_RS00640 (ETT64_00640)	-	91974..92117 (+)	144	WP_011185066.1	putative holin-like toxin	-
ETT64_RS00645 (ETT64_00645)	irvR	92979..93746 (-)	768	WP_003058809.1	helix-turn-helix transcriptional regulator	Regulator
ETT64_RS00650 (ETT64_00650)	-	93900..94106 (+)	207	WP_002992503.1	helix-turn-helix transcriptional regulator	-
ETT64_RS00655 (ETT64_00655)	-	94140..94340 (+)	201	WP_002992502.1	helix-turn-helix domain-containing protein	-
ETT64_RS00660 (ETT64_00660)	-	94361..94768 (+)	408	WP_002992501.1	hypothetical protein	-
ETT64_RS00665 (ETT64_00665)	-	94781..95410 (+)	630	WP_022555253.1	Rha family transcriptional regulator	-
ETT64_RS00670 (ETT64_00670)	-	95656..95997 (+)	342	WP_136293157.1	hypothetical protein	-
ETT64_RS00675 (ETT64_00675)	-	95984..96205 (+)	222	WP_010922763.1	hypothetical protein	-
ETT64_RS00680 (ETT64_00680)	-	96208..96399 (+)	192	WP_021775551.1	hypothetical protein	-
ETT64_RS00685 (ETT64_00685)	-	96411..96740 (+)	330	WP_003058810.1	hypothetical protein	-
ETT64_RS00690 (ETT64_00690)	-	96743..97015 (+)	273	WP_000051914.1	hypothetical protein	-
ETT64_RS00695 (ETT64_00695)	-	97016..97882 (+)	867	WP_136293156.1	primase alpha helix C-terminal domain-containing protein	-

Sequence

Protein

• Length: 255 a.a.
• Molecular weight: 28725.00 Da
• Isoelectric Point: 4.3544

>NTDB_id=301615 ETT64_RS00645 WP_003058809.1 92979..93746(-) (irvR) [Streptococcus pyogenes strain emm64.3]
MAKNSPQDLINREIFSTNLNMLMAKKNIKQIDIHNKLGIPKSTITGYVKGRSLPTAGNVQKLADFFGVLKSDIDPRFDSN
NIETNSNIIPSTLQKVTSTLSQLEHKRQLNVLDYAETQLEQQNTVEEPQATYYTYNYYDHAASAGTGQYLNDVQVETIEL
PVDYDADFVIPVYGDSMEPEYHSGDYVFIKLSINLSDGDIGVFEYYGDAYIKQLVINDSGAFLHSLNDKYDDILIDRDSD
FRIIGEVIGSFTSKS

Nucleotide

• Length: 768 bp

>NTDB_id=301615 ETT64_RS00645 WP_003058809.1 92979..93746(-) (irvR) [Streptococcus pyogenes strain emm64.3]
ATGGCTAAAAATAGTCCCCAAGATTTAATAAATAGAGAAATTTTCTCAACAAATCTCAACATGCTTATGGCTAAAAAGAA
TATCAAACAGATAGATATTCACAACAAACTAGGAATACCTAAGAGTACGATAACTGGCTATGTTAAAGGTCGTTCACTCC
CAACTGCTGGAAACGTTCAAAAGCTGGCGGACTTCTTCGGAGTTCTAAAATCAGACATTGACCCCCGTTTTGATTCTAAT
AATATTGAAACAAATAGTAATATTATCCCATCAACCCTACAAAAAGTAACATCTACTTTATCTCAGCTAGAACACAAGCG
ACAATTAAACGTCCTTGATTATGCTGAAACACAATTAGAACAACAAAACACAGTAGAAGAACCACAAGCCACCTACTACA
CTTACAATTACTACGACCACGCAGCTTCAGCTGGTACAGGTCAGTATCTAAATGATGTACAAGTAGAAACAATTGAATTA
CCAGTCGATTACGACGCTGATTTTGTCATACCGGTTTATGGCGATTCTATGGAACCCGAATACCATTCTGGGGACTATGT
ATTTATCAAACTATCTATTAACCTGTCAGATGGTGATATAGGAGTTTTTGAGTATTACGGTGATGCTTATATCAAACAAC
TTGTTATAAACGATTCTGGAGCGTTTCTGCATAGTCTGAACGACAAGTATGACGATATACTCATAGATAGAGATAGTGAT
TTCCGTATTATCGGAGAAGTTATTGGGAGTTTTACATCTAAATCATGA

Domains

Predicted by InterProScan.

• Helix-turn-helix (HTH_3) (23-68)

• Peptidase S24-like (Peptidase_S24) (141-248)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
irvR	Streptococcus mutans UA159	34	100	0.4